| UniProt ID | SP14L_HUMAN | |
|---|---|---|
| UniProt AC | Q9H930 | |
| Protein Name | Nuclear body protein SP140-like protein | |
| Gene Name | SP140L | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 580 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | GGGSDLSTRGLNGGV CCCCCCHHCCCCCCH | - | ||
| 65 | Phosphorylation | KRHKLEISNAIKKTF HHHHHHHHHHHHHHH | 30631047 | ||
| 73 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 86 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 87 | Ubiquitination | DRELITNKMFEDSED CHHHHHCCCCCCCCH | - | ||
| 111 | Phosphorylation | RVVYNVLSELEKTFN HHHHHHHHHHHHHCC | - | ||
| 120 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 145 | Ubiquitination | IHIYKSFKNAIQDKL HHHHHHHHHHHHHHH | - | ||
| 151 | Ubiquitination | FKNAIQDKLSFQESD HHHHHHHHHCCHHHC | - | ||
| 160 | Ubiquitination | SFQESDRKEREERPD CCHHHCHHHHHHCCC | 21906983 | ||
| 160 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 160 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 169 | Ubiquitination | REERPDIKLSLKQGE HHHCCCCCHHHHCCC | - | ||
| 169 | Sumoylation | REERPDIKLSLKQGE HHHCCCCCHHHHCCC | 28112733 | ||
| 173 | Ubiquitination | PDIKLSLKQGEVPES CCCCHHHHCCCCCCC | 21906983 | ||
| 173 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 173 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 180 | Phosphorylation | KQGEVPESPEARKES HCCCCCCCHHHHHHH | 30266825 | ||
| 187 | Phosphorylation | SPEARKESDQACGKM CHHHHHHHHCCCCCC | 26074081 | ||
| 196 | Phosphorylation | QACGKMDTVDIANNS CCCCCCCCEECCCCC | 27251275 | ||
| 203 | Phosphorylation | TVDIANNSTLGKPKR CEECCCCCCCCCCCC | 29255136 | ||
| 204 | Phosphorylation | VDIANNSTLGKPKRK EECCCCCCCCCCCCC | 29255136 | ||
| 207 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 207 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 207 | Ubiquitination | ANNSTLGKPKRKRRK CCCCCCCCCCCCCCC | - | ||
| 209 | Ubiquitination | NSTLGKPKRKRRKKK CCCCCCCCCCCCCCC | - | ||
| 225 | Phosphorylation | HGWSRMGTRTQKNNQ CCCCCCCCCCCCCCC | 22210691 | ||
| 229 | Ubiquitination | RMGTRTQKNNQQNDN CCCCCCCCCCCCCCC | - | ||
| 238 | Ubiquitination | NQQNDNSKADGQLVS CCCCCCCHHHHHHHC | 21906983 | ||
| 238 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 238 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 245 | Phosphorylation | KADGQLVSSEKKANM HHHHHHHCHHHHCCC | 29396449 | ||
| 246 | Phosphorylation | ADGQLVSSEKKANMN HHHHHHCHHHHCCCC | 21815630 | ||
| 248 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 248 | Ubiquitination | GQLVSSEKKANMNLK HHHHCHHHHCCCCHH | 2190698 | ||
| 248 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 248 | Acetylation | GQLVSSEKKANMNLK HHHHCHHHHCCCCHH | 25953088 | ||
| 249 | Ubiquitination | QLVSSEKKANMNLKD HHHCHHHHCCCCHHH | - | ||
| 255 | Acetylation | KKANMNLKDLSKIRG HHCCCCHHHHHHHCC | 19807525 | ||
| 255 | Ubiquitination | KKANMNLKDLSKIRG HHCCCCHHHHHHHCC | - | ||
| 290 | Ubiquitination | VRSRASRKHKDETVD HHHHHHHHCCCCCCC | - | ||
| 292 | Sumoylation | SRASRKHKDETVDFQ HHHHHHCCCCCCCCC | - | ||
| 292 | Sumoylation | SRASRKHKDETVDFQ HHHHHHCCCCCCCCC | 28112733 | ||
| 318 | Ubiquitination | KGILHKEKLEQGTLA HHHCCHHHCCCCCCC | - | ||
| 323 | Phosphorylation | KEKLEQGTLAKCIQT HHHCCCCCCCEEEEC | 24532841 | ||
| 330 | Phosphorylation | TLAKCIQTEDGKWFT CCCEEEECCCCCEEC | 24532841 | ||
| 334 | Ubiquitination | CIQTEDGKWFTPMEF EEECCCCCEECCEEE | - | ||
| 389 | Ubiquitination | RNKKRILKSQNNSSV CCHHHHHHCCCCCCC | - | ||
| 449 | Ubiquitination | NCIFCRMKESPGSQQ CEEEEEECCCCCHHH | - | ||
| 451 | Phosphorylation | IFCRMKESPGSQQCC EEEEECCCCCHHHCC | 30108239 | ||
| 454 | Phosphorylation | RMKESPGSQQCCQES EECCCCCHHHCCCHH | 30108239 | ||
| 497 | Phosphorylation | SFFAKIPYYYYIREA HHHHHCCHHHHHHHH | - | ||
| 509 | Ubiquitination | REACQGLKEPMWLDK HHHHHCCCCCCHHHH | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SP14L_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SP14L_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SP14L_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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