PSG1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSG1_HUMAN
• UniProt AC: P11464
• Protein Name: Pregnancy-specific beta-1-glycoprotein 1
• Gene Name: PSG1
• Organism: Homo sapiens (Human).
• Sequence Length: 419
• Subcellular Localization: Secreted .
• Protein Sequence: MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	N-linked_Glycosylation	LVHNLPQNLTGYIWY EEECCCCCCCEEEEE	37.32	UniProtKB CARBOHYD
102	Phosphorylation	YSGRETAYSNASLLI CCCCCHHHCCCEEEE	15.18	27067055
104	N-linked_Glycosylation	GRETAYSNASLLIQN CCCHHHCCCEEEEEC	22.37	UniProtKB CARBOHYD
106	Phosphorylation	ETAYSNASLLIQNVT CHHHCCCEEEEECCC	28.14	27067055
111	N-linked_Glycosylation	NASLLIQNVTREDAG CCEEEEECCCHHHCC	30.08	UniProtKB CARBOHYD
113	Phosphorylation	SLLIQNVTREDAGSY EEEEECCCHHHCCEE	35.57	27067055
119	Phosphorylation	VTREDAGSYTLHIIK CCHHHCCEEEEEEEE	19.37	24719451
150	Phosphorylation	HLETPKPSISSSNLN EEECCCCCCCCCCCC	41.03	30631047
154	Phosphorylation	PKPSISSSNLNPRET CCCCCCCCCCCHHHH	38.25	30631047
196	Phosphorylation	MTHSLKLSETNRTLF CCEEEEECCCCCEEE	40.56	28176443
198	Phosphorylation	HSLKLSETNRTLFLL EEEEECCCCCEEEEE	26.99	28176443
199	N-linked_Glycosylation	SLKLSETNRTLFLLG EEEECCCCCEEEEEE	30.78	UniProtKB CARBOHYD
201	Phosphorylation	KLSETNRTLFLLGVT EECCCCCEEEEEEEC	24.75	28176443
208	Phosphorylation	TLFLLGVTKYTAGPY EEEEEEECEECCCCC	19.28	28176443
228	Phosphorylation	NPVSASRSDPVTLNL CCCCCCCCCCEEEEC	43.71	24888630
259	N-linked_Glycosylation	RENKDVLNFTCEPKS CCCCCCCEEEECCCC	29.99	UniProtKB CARBOHYD
268	N-linked_Glycosylation	TCEPKSENYTYIWWL EECCCCCCEEEEEEE	41.35	UniProtKB CARBOHYD
271	Phosphorylation	PKSENYTYIWWLNGQ CCCCCEEEEEEECCC	5.56	-
279	Phosphorylation	IWWLNGQSLPVSPRV EEEECCCCCCCCCCC	35.72	-
283	Phosphorylation	NGQSLPVSPRVKRPI CCCCCCCCCCCCCCC	12.68	-
301	Phosphorylation	ILILPSVTRNETGPY EEEECCCCCCCCCCE	31.92	24719451
303	N-linked_Glycosylation	ILPSVTRNETGPYQC EECCCCCCCCCCEEE	41.64	UniProtKB CARBOHYD
321	Phosphorylation	DRYGGIRSDPVTLNV CCCCCCCCCCEEEEE	44.33	-
325	Phosphorylation	GIRSDPVTLNVLYGP CCCCCCEEEEEEECC	20.29	-
330	Phosphorylation	PVTLNVLYGPDLPRI CEEEEEEECCCCCCC	23.48	23663014
395	Phosphorylation	HSGLYVCSVRNSATG CCEEEEEEEECCCCC	17.67	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSG1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSG1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSG1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UT14A_HUMAN	UTP14A	physical	16169070
OGT1_HUMAN	OGT	physical	25416956
TBB8_HUMAN	TUBB8	physical	26186194
USF2_HUMAN	USF2	physical	26186194
USF1_HUMAN	USF1	physical	26186194
PYC_HUMAN	PC	physical	26186194
UBR1_HUMAN	UBR1	physical	26186194
EST1A_HUMAN	SMG6	physical	26186194
ACACA_HUMAN	ACACA	physical	26186194
PARN_HUMAN	PARN	physical	26186194
PSG9_HUMAN	PSG9	physical	26186194
PSG6_HUMAN	PSG6	physical	26186194
PSG5_HUMAN	PSG5	physical	26186194
FAD1_HUMAN	FLAD1	physical	26186194
STK39_HUMAN	STK39	physical	26186194
ATG7_HUMAN	ATG7	physical	26186194
FBLN1_HUMAN	FBLN1	physical	26186194
ANR46_HUMAN	ANKRD46	physical	26186194
SLIK5_HUMAN	SLITRK5	physical	26186194
LEG1_HUMAN	LGALS1	physical	26186194
MANEA_HUMAN	MANEA	physical	26186194
PSG4_HUMAN	PSG4	physical	28514442
IKKB_HUMAN	IKBKB	physical	28514442
IKKA_HUMAN	CHUK	physical	28514442
TBB1_HUMAN	TUBB1	physical	28514442
CELR3_HUMAN	CELSR3	physical	28514442
KLH25_HUMAN	KLHL25	physical	28514442
EF1A2_HUMAN	EEF1A2	physical	28514442
SDF2L_HUMAN	SDF2L1	physical	28514442
LRP12_HUMAN	LRP12	physical	28514442
ANR46_HUMAN	ANKRD46	physical	28514442
CBPE_HUMAN	CPE	physical	28514442
ACACA_HUMAN	ACACA	physical	28514442
EST1A_HUMAN	SMG6	physical	28514442
SORL_HUMAN	SORL1	physical	28514442
FAT3_HUMAN	FAT3	physical	28514442
IF1AX_HUMAN	EIF1AX	physical	28514442
COEA1_HUMAN	COL14A1	physical	28514442
MEGF8_HUMAN	MEGF8	physical	28514442
TBA4A_HUMAN	TUBA4A	physical	28514442
SDF2_HUMAN	SDF2	physical	28514442
PPT2_HUMAN	PPT2	physical	28514442
NID1_HUMAN	NID1	physical	28514442
TECT1_HUMAN	TCTN1	physical	28514442
PCOC2_HUMAN	PCOLCE2	physical	28514442
NPC2_HUMAN	NPC2	physical	28514442
LAMB2_HUMAN	LAMB2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.