PSG4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSG4_HUMAN
• UniProt AC: Q00888
• Protein Name: Pregnancy-specific beta-1-glycoprotein 4
• Gene Name: PSG4
• Organism: Homo sapiens (Human).
• Sequence Length: 419
• Subcellular Localization: Secreted .
• Protein Sequence: MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MGPLSAPPCTQR ---CCCCCCCCCCCC	41.69	24043423
10	Phosphorylation	PLSAPPCTQRITWKG CCCCCCCCCCCCCCH	27.02	24043423
102	Phosphorylation	YSGRERVYSNASLLI CCCCCHHHCCCEEEE	11.48	29978859
103	Phosphorylation	SGRERVYSNASLLIQ CCCCHHHCCCEEEEE	24.06	29978859
104	N-linked_Glycosylation	GRERVYSNASLLIQN CCCHHHCCCEEEEEC	18.83	UniProtKB CARBOHYD
106	Phosphorylation	ERVYSNASLLIQNVT CHHHCCCEEEEECCC	28.14	29978859
111	N-linked_Glycosylation	NASLLIQNVTQEDAG CCEEEEECCCHHHCC	31.63	UniProtKB CARBOHYD
113	Phosphorylation	SLLIQNVTQEDAGSY EEEEECCCHHHCCEE	33.52	29978859
119	Phosphorylation	VTQEDAGSYTLHIIK CCHHHCCEEEEEEEE	19.37	24719451
120	Phosphorylation	TQEDAGSYTLHIIKR CHHHCCEEEEEEEEE	16.65	29978859
121	Phosphorylation	QEDAGSYTLHIIKRR HHHCCEEEEEEEEEC	17.35	29978859
150	Phosphorylation	HLETPKPSISSSNLN EECCCCCCCCCCCCC	41.03	30631047
154	Phosphorylation	PKPSISSSNLNPREA CCCCCCCCCCCHHHH	38.25	30631047
199	N-linked_Glycosylation	RLQLSKTNRTLFIFG EEEECCCCCEEEEEE	38.38	UniProtKB CARBOHYD
215	Phosphorylation	TKYIAGPYECEIRNP CCCCCCCCEEEECCC	32.09	-
228	Phosphorylation	NPVSASRSDPVTLNL CCCCCCCCCCCEECC	43.71	24888630
268	N-linked_Glycosylation	TCEPKSKNYTYIWWL EECCCCCCEEEEEEE	41.28	UniProtKB CARBOHYD
271	Phosphorylation	PKSKNYTYIWWLNGQ CCCCCEEEEEEECCC	5.56	-
279	Phosphorylation	IWWLNGQSLPVSPRV EEEECCCCCCCCCCC	35.72	-
283	Phosphorylation	NGQSLPVSPRVKRPI CCCCCCCCCCCCCCC	12.68	-
299	N-linked_Glycosylation	NRILILPNVTRNETG CCEEEECCCCCCCCC	44.33	UniProtKB CARBOHYD
303	N-linked_Glycosylation	ILPNVTRNETGPYQC EECCCCCCCCCCEEC	41.64	UniProtKB CARBOHYD
321	Phosphorylation	DRYGGIRSDPVTLNV CCCCCCCCCCEEEEE	44.33	-
325	Phosphorylation	GIRSDPVTLNVLYGP CCCCCCEEEEEEECC	20.29	-
336	Phosphorylation	LYGPDLPSIYPSFTY EECCCCCCCCCEEEE	41.89	-
380	Phosphorylation	QLSGQKLSIPQITTK EECCCEEECCEEEEC	38.98	20873877
385	Phosphorylation	KLSIPQITTKHSGLY EEECCEEEECCCEEE	25.25	20873877
386	Phosphorylation	LSIPQITTKHSGLYA EECCEEEECCCEEEE	28.52	20873877
389	Phosphorylation	PQITTKHSGLYACSV CEEEECCCEEEEEEE	31.86	20873877
392	Phosphorylation	TTKHSGLYACSVRNS EECCCEEEEEEEECC	14.75	20873877
395	Phosphorylation	HSGLYACSVRNSATG CCEEEEEEEECCCCC	18.88	20873877
399	Phosphorylation	YACSVRNSATGKESS EEEEEECCCCCCCCC	19.35	-
406	Phosphorylation	SATGKESSKSITVKV CCCCCCCCCEEEEEE	31.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSG4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSG4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSG4_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PSG4_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.