PSG9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSG9_HUMAN
• UniProt AC: Q00887
• Protein Name: Pregnancy-specific beta-1-glycoprotein 9
• Gene Name: PSG9
• Organism: Homo sapiens (Human).
• Sequence Length: 426
• Subcellular Localization: Secreted .
• Protein Sequence: MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQNLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVSGPCHGDLTESQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
91	Phosphorylation	VDGKIIIYGPAYSGR CCCEEEEECCCCCCC	13.47	21214269
100	Phosphorylation	PAYSGRETVYSNASL CCCCCCCHHHCCCEE	24.31	-
104	N-linked_Glycosylation	GRETVYSNASLLIQN CCCHHHCCCEEEEEC	18.83	UniProtKB CARBOHYD
111	N-linked_Glycosylation	NASLLIQNVTRKDAG CCEEEEECCCCCCCC	30.08	UniProtKB CARBOHYD
120	Phosphorylation	TRKDAGTYTLHIIKR CCCCCCEEEEEEEEC	13.34	-
121	Phosphorylation	RKDAGTYTLHIIKRG CCCCCEEEEEEEECC	16.23	-
143	Phosphorylation	RHFTFTLYLETPKPY HEEEEEEEECCCCCC	10.23	19845377
153	Phosphorylation	TPKPYISSSNLNPRE CCCCCCCCCCCCHHH	17.43	19845377
154	Phosphorylation	PKPYISSSNLNPREA CCCCCCCCCCCHHHH	38.25	19845377
199	N-linked_Glycosylation	RLQLSKTNRTLYLFG EEEECCCCCEEEEEE	38.38	UniProtKB CARBOHYD
210	Phosphorylation	YLFGVTKYIAGPYEC EEEEECEEECCCCCC	6.14	-
215	Phosphorylation	TKYIAGPYECEIRNP CEEECCCCCCEECCC	32.09	-
228	Phosphorylation	NPVSASRSDPVTLNL CCCCCCCCCCEEEEC	43.71	24888630
243	Phosphorylation	LPKLPIPYITINNLN CCCCCCCEEEECCCC	16.06	-
268	N-linked_Glycosylation	TCEPKSENYTYIWWL EECCCCCCEEEEEEE	41.35	UniProtKB CARBOHYD
271	Phosphorylation	PKSENYTYIWWLNGQ CCCCCEEEEEEECCC	5.56	-
301	Phosphorylation	ILILPSVTRNETGPY EEEECCCCCCCCCCE	31.92	24719451
303	N-linked_Glycosylation	ILPSVTRNETGPYQC EECCCCCCCCCCEEC	41.64	UniProtKB CARBOHYD
387	N-linked_Glycosylation	FIPQITRNHSGLYAC EECEECCCCCCEEEE	25.65	UniProtKB CARBOHYD
389	Phosphorylation	PQITRNHSGLYACSV CEECCCCCCEEEEEE	33.76	-
392	Phosphorylation	TRNHSGLYACSVHNS CCCCCCEEEEEEEEC	14.75	22210691
399	Phosphorylation	YACSVHNSATGKEIS EEEEEEECCCCCCCC	16.60	22210691
401	Phosphorylation	CSVHNSATGKEISKS EEEEECCCCCCCCCC	48.91	22210691
406	Phosphorylation	SATGKEISKSMTVKV CCCCCCCCCCEEEEE	21.55	22210691
414	Phosphorylation	KSMTVKVSGPCHGDL CCEEEEEECCCCCCC	31.16	-
422	Phosphorylation	GPCHGDLTESQS--- CCCCCCCCCCCC---	38.03	-
424	Phosphorylation	CHGDLTESQS----- CCCCCCCCCC-----	30.41	-
426	Phosphorylation	GDLTESQS------- CCCCCCCC-------	52.01	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSG9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSG9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSG9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1A1_HUMAN	EEF1A1	physical	16169070
LRIF1_HUMAN	LRIF1	physical	16169070
VATE1_HUMAN	ATP6V1E1	physical	26186194
SBP2L_HUMAN	SECISBP2L	physical	26186194
GT252_HUMAN	COLGALT2	physical	26186194
NFL_HUMAN	NEFL	physical	26186194
NFM_HUMAN	NEFM	physical	26186194
SHCBP_HUMAN	SHCBP1	physical	26186194
APOL2_HUMAN	APOL2	physical	26186194
CC85C_HUMAN	CCDC85C	physical	26186194
ZMYM1_HUMAN	ZMYM1	physical	26186194
ZBT44_HUMAN	ZBTB44	physical	26186194
CELR3_HUMAN	CELSR3	physical	26186194
SHCBP_HUMAN	SHCBP1	physical	28514442
SBP2L_HUMAN	SECISBP2L	physical	28514442
PSG1_HUMAN	PSG1	physical	28514442
ZBT44_HUMAN	ZBTB44	physical	28514442
CELR3_HUMAN	CELSR3	physical	28514442
GT252_HUMAN	COLGALT2	physical	28514442
ZMYM1_HUMAN	ZMYM1	physical	28514442
CC85C_HUMAN	CCDC85C	physical	28514442
APOL2_HUMAN	APOL2	physical	28514442
VATE1_HUMAN	ATP6V1E1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.