ZMYM1_HUMAN - dbPTM
ZMYM1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZMYM1_HUMAN
UniProt AC Q5SVZ6
Protein Name Zinc finger MYM-type protein 1
Gene Name ZMYM1
Organism Homo sapiens (Human).
Sequence Length 1142
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MKEPLLGGECDKAVASQLGLLDEIKTEPDNAQEYCHRQQSRTQENELKINAVFSESASQLTAGIQLSLASSGVNKMLPSVSTTAIQVSCAGCKKILQKGQTAYQRKGSAQLFCSIPCITEYISSASSPVPSKRTCSNCSKDILNPKDVISVQLEDTTSCKTFCSLSCLSSYEEKRKPFVTICTNSILTKCSMCQKTAIIQYEVKYQNVKHNLCSNACLSKFHSANNFIMNCCENCGTYCYTSSSLSHILQMEGQSHYFNSSKSITAYKQKPAKPLISVPCKPLKPSDEMIETTSDLGKTELFCSINCFSAYSKAKMESSSVSVVSVVHDTSTELLSPKKDTTPVISNIVSLADTDVALPIMNTDVLQDTVSSVTATADVIVDLSKSSPSEPSNAVASSSTEQPSVSPSSSVFSQHAIGSSTEVQKDNMKSMKISDELCHPKCTSKVQKVKGKSRSIKKSCCADFECLENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLSIHSKQIEGNKKYLKLIIENILFLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRLMNSQVDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRYPQKSSKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSIIRFCKEVKELRSALKTLSSLFNTICMSGEMLANFRNIYRLSQNKTCKKHISQSCWTVHDRTLLSVIDSLPEIIETLEVIASHSSNTSFADELSHLLTLVSKFEFVFCLKFLYRVLSVTGILSKELQNKTIDIFSLSSKIEAILECLSSERNDVYFKTIWDGTEEICQKITCKGFKVEKPSLQKRRKIQKSVDLGNSDNMFFPTSTEEQYKINIYYQGLDTILQNLKLCFSEFDYCKIKQISELLFKWNEPLNETTAKHVQEFYKLDEDIIPELRFYRHYAKLNFVIDDSCINFVSLGCLFIQHGLHSNIPCLSKLLYIALSWPITSASTENSFSTLPRLKTYLCNTMGQEKLTGPALMAVEQELVNKLMEPERLNEIVEKFISQMKEI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Ubiquitination------MKEPLLGGE
------CCCCCCCCC		78.37-
12UbiquitinationLLGGECDKAVASQLG
CCCCCCCHHHHHHHC		57.32-
25SumoylationLGLLDEIKTEPDNAQ
HCCHHHHCCCCCCHH		44.80-
25SumoylationLGLLDEIKTEPDNAQ
HCCHHHHCCCCCCHH		44.8028112733
25UbiquitinationLGLLDEIKTEPDNAQ
HCCHHHHCCCCCCHH		44.80-
34PhosphorylationEPDNAQEYCHRQQSR
CCCCHHHHHHHHHCC		4.9725884760
94UbiquitinationVSCAGCKKILQKGQT
HHCCCHHHHHHCCCC		53.37-
98SumoylationGCKKILQKGQTAYQR
CHHHHHHCCCCHHHC		49.92-
98AcetylationGCKKILQKGQTAYQR
CHHHHHHCCCCHHHC		49.9225953088
98SumoylationGCKKILQKGQTAYQR
CHHHHHHCCCCHHHC		49.92-
98UbiquitinationGCKKILQKGQTAYQR
CHHHHHHCCCCHHHC		49.9221906983
108PhosphorylationTAYQRKGSAQLFCSI
CHHHCCCCHHHHCCC		18.8427251275
123PhosphorylationPCITEYISSASSPVP
HHHHHHHHHCCCCCC		20.9628348404
124PhosphorylationCITEYISSASSPVPS
HHHHHHHHCCCCCCC		23.7028348404
126PhosphorylationTEYISSASSPVPSKR
HHHHHHCCCCCCCCC		36.8028348404
127PhosphorylationEYISSASSPVPSKRT
HHHHHCCCCCCCCCC		29.6325159151
146UbiquitinationSKDILNPKDVISVQL
CCCCCCHHHCEEEEE		64.65-
150PhosphorylationLNPKDVISVQLEDTT
CCHHHCEEEEECCCC		12.03-
176AcetylationSSYEEKRKPFVTICT
CCHHHHCCCCEEEEC		54.6019823671
185PhosphorylationFVTICTNSILTKCSM
CEEEECHHHHHHCCC		10.7924719451
209UbiquitinationEVKYQNVKHNLCSNA
EECHHCCCCCCCCHH		34.03-
263PhosphorylationHYFNSSKSITAYKQK
CCCCCCCCEEEECCC		27.4124719451
265PhosphorylationFNSSKSITAYKQKPA
CCCCCCEEEECCCCC		30.9024719451
267PhosphorylationSSKSITAYKQKPAKP
CCCCEEEECCCCCCC		12.8024719451
284SumoylationSVPCKPLKPSDEMIE
ECCCCCCCCCHHHCC		51.51-
284SumoylationSVPCKPLKPSDEMIE
ECCCCCCCCCHHHCC		51.5128112733
286PhosphorylationPCKPLKPSDEMIETT
CCCCCCCCHHHCCCC		44.6129449344
292PhosphorylationPSDEMIETTSDLGKT
CCHHHCCCCCCCCCC		22.2220873877
293PhosphorylationSDEMIETTSDLGKTE
CHHHCCCCCCCCCCE		13.8820873877
294PhosphorylationDEMIETTSDLGKTEL
HHHCCCCCCCCCCEE		37.9520873877
299PhosphorylationTTSDLGKTELFCSIN
CCCCCCCCEEEEEEC		35.8030576142
322PhosphorylationKMESSSVSVVSVVHD
HHCCCCCEEEEEEEC		20.8122199227
325PhosphorylationSSSVSVVSVVHDTST
CCCCEEEEEEECCCC		19.1030576142
330PhosphorylationVVSVVHDTSTELLSP
EEEEEECCCCCCCCC		23.7530576142
331PhosphorylationVSVVHDTSTELLSPK
EEEEECCCCCCCCCC		26.4130576142
332PhosphorylationSVVHDTSTELLSPKK
EEEECCCCCCCCCCC		32.5122199227
336PhosphorylationDTSTELLSPKKDTTP
CCCCCCCCCCCCCCC		47.5030576142
386PhosphorylationVIVDLSKSSPSEPSN
EEEECHHCCCCCCCC		44.0726074081
387PhosphorylationIVDLSKSSPSEPSNA
EEECHHCCCCCCCCC		35.8625159151
389PhosphorylationDLSKSSPSEPSNAVA
ECHHCCCCCCCCCCC		65.1825159151
392PhosphorylationKSSPSEPSNAVASSS
HCCCCCCCCCCCCCC		33.1123663014
397PhosphorylationEPSNAVASSSTEQPS
CCCCCCCCCCCCCCC		20.4427174698
398PhosphorylationPSNAVASSSTEQPSV
CCCCCCCCCCCCCCC		31.3827174698
399PhosphorylationSNAVASSSTEQPSVS
CCCCCCCCCCCCCCC		33.2127174698
400PhosphorylationNAVASSSTEQPSVSP
CCCCCCCCCCCCCCC		40.3623663014
404PhosphorylationSSSTEQPSVSPSSSV
CCCCCCCCCCCCCHH		34.6223663014
406PhosphorylationSTEQPSVSPSSSVFS
CCCCCCCCCCCHHHC		24.3323663014
408PhosphorylationEQPSVSPSSSVFSQH
CCCCCCCCCHHHCCC		27.9523663014
409PhosphorylationQPSVSPSSSVFSQHA
CCCCCCCCHHHCCCC		33.6323663014
410PhosphorylationPSVSPSSSVFSQHAI
CCCCCCCHHHCCCCC		31.3623663014
413PhosphorylationSPSSSVFSQHAIGSS
CCCCHHHCCCCCCCC		20.9227174698
419PhosphorylationFSQHAIGSSTEVQKD
HCCCCCCCCCHHHHH		28.1523663014
420PhosphorylationSQHAIGSSTEVQKDN
CCCCCCCCCHHHHHH		24.3127174698
421PhosphorylationQHAIGSSTEVQKDNM
CCCCCCCCHHHHHHH		41.7026074081
441UbiquitinationSDELCHPKCTSKVQK
CCCCCCHHHCCCHHH		26.86-
458UbiquitinationGKSRSIKKSCCADFE
CCCCCCHHHHHCCHH		47.24-
459PhosphorylationKSRSIKKSCCADFEC
CCCCCHHHHHCCHHH		14.9328555341
471UbiquitinationFECLENSKKDVAFCY
HHHHHCCCCHHHHHH		65.65-
494PhosphorylationYFSCGRESFATHGTS
HHCCCCHHHHCCCCC		20.8629083192
497PhosphorylationCGRESFATHGTSNWK
CCCHHHHCCCCCHHH		20.8729083192
500PhosphorylationESFATHGTSNWKKTL
HHHHCCCCCHHHHHH		15.9829083192
501PhosphorylationSFATHGTSNWKKTLE
HHHCCCCCHHHHHHH		45.3329083192
521UbiquitinationEKSEMHLKSLEFWRE
HHCHHHHHHHHHHHH		38.0121906983
529PhosphorylationSLEFWREYQFCDGAV
HHHHHHHHCCCCCCC		9.7927174698
537PhosphorylationQFCDGAVSDDLSIHS
CCCCCCCCCCCEEEH		25.5227174698
541PhosphorylationGAVSDDLSIHSKQIE
CCCCCCCEEEHHHCC		25.8327174698
544PhosphorylationSDDLSIHSKQIEGNK
CCCCEEEHHHCCCCH		25.2827174698
545UbiquitinationDDLSIHSKQIEGNKK
CCCEEEHHHCCCCHH		40.93-
551UbiquitinationSKQIEGNKKYLKLII
HHHCCCCHHHHHHHH		54.36-
552UbiquitinationKQIEGNKKYLKLIIE
HHCCCCHHHHHHHHH		60.87-
583UbiquitinationQSVSSVNKGNFLELL
CCCCCCCCCCHHHHH		53.74-
607PhosphorylationETFRLMNSQVDFYNS
HHHHHHHHCCCCCCC		20.0218669648
612PhosphorylationMNSQVDFYNSTQIQS
HHHCCCCCCCCCCCH		12.0718669648
614PhosphorylationSQVDFYNSTQIQSDI
HCCCCCCCCCCCHHH		15.4318669648
615PhosphorylationQVDFYNSTQIQSDII
CCCCCCCCCCCHHHH		26.5018669648
619PhosphorylationYNSTQIQSDIIEIIK
CCCCCCCHHHHHHHH		32.1918669648
671UbiquitinationRYPQKSSKAILIKER
HCCCCCCCEEEEEEE		46.6821906983
676UbiquitinationSSKAILIKERFLGFV
CCCEEEEEEECCCCC		39.12-
698UbiquitinationTHLHRTIKTYLQQIG
HHHHHHHHHHHHHHC		30.4221906983
710UbiquitinationQIGVDMDKIHGQAYD
HHCCCHHHHCCEEEC		29.93-
723UbiquitinationYDSTTNLKIKFNKIA
ECCCCCEEEEEHHHH		46.01-
728UbiquitinationNLKIKFNKIAAEFKK
CEEEEEHHHHHHHHC		36.53-
742PhosphorylationKEEPRALYIHCYAHF
CCCCCEEEHHHHHHH		6.4020860994
746PhosphorylationRALYIHCYAHFLDLS
CEEEHHHHHHHHHHH		6.7520860994
753PhosphorylationYAHFLDLSIIRFCKE
HHHHHHHHHHHHHHH		18.6820860994
769AcetylationKELRSALKTLSSLFN
HHHHHHHHHHHHHHH		47.3226051181
866PhosphorylationVFCLKFLYRVLSVTG
HHHHHHHHHHHHHHC		11.21-
876PhosphorylationLSVTGILSKELQNKT
HHHHCHHCHHHCCCC		23.36-
901PhosphorylationEAILECLSSERNDVY
HHHHHHHCCCCCCEE		41.6427542207
902PhosphorylationAILECLSSERNDVYF
HHHHHHCCCCCCEEE		27.8527542207
922UbiquitinationGTEEICQKITCKGFK
CHHHHHHHHCCCCCC		35.26-
926AcetylationICQKITCKGFKVEKP
HHHHHCCCCCCCCCC		59.7520167786
929UbiquitinationKITCKGFKVEKPSLQ
HHCCCCCCCCCCCHH		59.14-
937AcetylationVEKPSLQKRRKIQKS
CCCCCHHHHHCHHHH		60.5126051181
943UbiquitinationQKRRKIQKSVDLGNS
HHHHCHHHHHCCCCC		56.7921906983
944PhosphorylationKRRKIQKSVDLGNSD
HHHCHHHHHCCCCCC		12.4225159151
992UbiquitinationEFDYCKIKQISELLF
HCCHHHHHHHHHHHH		27.37-
1011UbiquitinationPLNETTAKHVQEFYK
CCCHHHHHHHHHHHH		42.06-
1018UbiquitinationKHVQEFYKLDEDIIP
HHHHHHHHCCCCCHH		55.5821906983
1088PhosphorylationASTENSFSTLPRLKT
CCCCCCCCCHHHHHH		28.9323312004
1089PhosphorylationSTENSFSTLPRLKTY
CCCCCCCCHHHHHHH		38.4824719451
1094AcetylationFSTLPRLKTYLCNTM
CCCHHHHHHHHHCCC		36.0826051181
1094UbiquitinationFSTLPRLKTYLCNTM
CCCHHHHHHHHHCCC		36.08-
1121UbiquitinationVEQELVNKLMEPERL
HHHHHHHHHCCHHHH		41.55-
1140UbiquitinationEKFISQMKEI-----
HHHHHHHHCC-----		44.6221906983
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZMYM1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZMYM1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZMYM1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ZMYM1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZMYM1_HUMAN

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-944, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory