ANR46_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANR46_HUMAN
• UniProt AC: Q86W74
• Protein Name: Ankyrin repeat domain-containing protein 46
• Gene Name: ANKRD46
• Organism: Homo sapiens (Human).
• Sequence Length: 232
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYRRTLRLGSFARQDRSRIQAI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
116	Ubiquitination	ATPLVLAKRRGVNKD CCHHHHHHHCCCCHH	38.17	-
137	Ubiquitination	SLEEQEVKGFNRGTH HHHHHHCCCCCCCCC	57.96	21890473
137 (in isoform 1)	Ubiquitination	-	57.96	21890473
137 (in isoform 2)	Ubiquitination	-	57.96	21890473
146	Ubiquitination	FNRGTHSKLETMQTA CCCCCCHHHHHHHHH	42.62	-
215	Phosphorylation	GIAYYRRTLRLGSFA HHHHHHHHHHHHHHH	13.77	113324987

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANR46_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANR46_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANR46_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ANR46_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.