PSG6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSG6_HUMAN
• UniProt AC: Q00889
• Protein Name: Pregnancy-specific beta-1-glycoprotein 6
• Gene Name: PSG6
• Organism: Homo sapiens (Human).
• Sequence Length: 435
• Subcellular Localization: Secreted .
• Protein Sequence: MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASPQVTYAGPNTWFQEILLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	N-linked_Glycosylation	LVHNLPQNLTGYIWY EEECCCCCCCEEEEE	37.32	UniProtKB CARBOHYD
99	Phosphorylation	PAYSGRETVYSNASL CCCCCCCEECCCCEE	24.31	-
103	N-linked_Glycosylation	GRETVYSNASLLIQN CCCEECCCCEEEEEC	18.83	UniProtKB CARBOHYD
110	N-linked_Glycosylation	NASLLIQNVTQEDAG CCEEEEECCCHHHCC	31.63	UniProtKB CARBOHYD
118	Phosphorylation	VTQEDAGSYTLHIIK CCHHHCCEEEEEEEE	19.37	24719451
198	N-linked_Glycosylation	RLQLSKTNRTLYLFG EEEECCCCCEEEEEE	38.38	UniProtKB CARBOHYD
209	Phosphorylation	YLFGVTKYIAGPYEC EEEEEEEEECCCCCC	6.14	-
214	Phosphorylation	TKYIAGPYECEIRNP EEEECCCCCCEECCC	32.09	-
227	Phosphorylation	NPVSASRSDPVTLNL CCCCCCCCCCEEEEC	43.71	24888630
267	N-linked_Glycosylation	TCEPKSRNYTYIWWL EECCCCCCEEEEEEE	40.36	UniProtKB CARBOHYD
278	Phosphorylation	IWWLNGQSLPVSPRV EEEECCCCCCCCCCC	35.72	-
282	Phosphorylation	NGQSLPVSPRVKRPI CCCCCCCCCCCCCCC	12.68	-
300	Phosphorylation	ILILPSVTRNETGPY EEEECCCCCCCCCCE	31.92	24719451
302	N-linked_Glycosylation	ILPSVTRNETGPYQC EECCCCCCCCCCEEC	41.64	UniProtKB CARBOHYD
329	Phosphorylation	PVTLNVLYGPDLPRI CEEEEEEECCCCCCC	23.48	-
386	N-linked_Glycosylation	FIPQITTNHSGLYAC EECEECCCCCCEEEE	20.76	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSG6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSG6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSG6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PSG6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.