TM52B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM52B_HUMAN
• UniProt AC: Q4KMG9
• Protein Name: Transmembrane protein 52B
• Gene Name: TMEM52B
• Organism: Homo sapiens (Human).
• Sequence Length: 183
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MGVRVHVVAASALLYFILLSGTRCEENCGNPEHCLTTDWVHLWYIWLLVVIGALLLLCGLTSLCFRCCCLSRQQNGEDGGPPPCEVTVIAFDHDSTLQSTITSLQSVFGPAARRILAVAHSHSSLGQLPSSLDTLPGYEEALHMSRFTVAMCGQKAPDLPPVPEEKQLPPTEKESTRIVDSWN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
130	Phosphorylation	SSLGQLPSSLDTLPG CCCCCCCCCHHCCCC		-
148	Phosphorylation	ALHMSRFTVAMCGQK HHHHHHHHHHHCCCC		29759185
181	Phosphorylation	ESTRIVDSWN----- HHCCCCCCCC-----		29759185

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM52B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM52B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM52B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
THA11_HUMAN	THAP11	physical	26186194
NED4L_HUMAN	NEDD4L	physical	26186194
NEDD4_HUMAN	NEDD4	physical	26186194
RHDF2_HUMAN	RHBDF2	physical	26186194
AT2B4_HUMAN	ATP2B4	physical	26186194
AN13D_HUMAN	ANKRD13D	physical	26186194
FCN1_HUMAN	FCN1	physical	26186194
VGFR3_HUMAN	FLT4	physical	26186194
RAB6A_HUMAN	RAB6A	physical	26186194
ZDHC9_HUMAN	ZDHHC9	physical	26186194
COR2A_HUMAN	CORO2A	physical	26186194
LRBA_HUMAN	LRBA	physical	26186194
TAB1_HUMAN	TAB1	physical	26186194
TM205_HUMAN	TMEM205	physical	26186194
WDR44_HUMAN	WDR44	physical	26186194
NED4L_HUMAN	NEDD4L	physical	28514442
RHDF2_HUMAN	RHBDF2	physical	28514442
NEDD4_HUMAN	NEDD4	physical	28514442
PK3CA_HUMAN	PIK3CA	physical	28514442
PKP2_HUMAN	PKP2	physical	28514442
S26A2_HUMAN	SLC26A2	physical	28514442
PHLB3_HUMAN	PHLDB3	physical	28514442
MYADM_HUMAN	MYADM	physical	28514442
AN13D_HUMAN	ANKRD13D	physical	28514442
MFAP3_HUMAN	MFAP3	physical	28514442
PKP4_HUMAN	PKP4	physical	28514442
TM205_HUMAN	TMEM205	physical	28514442
THA11_HUMAN	THAP11	physical	28514442
BMR1A_HUMAN	BMPR1A	physical	28514442
VGFR3_HUMAN	FLT4	physical	28514442
P55G_HUMAN	PIK3R3	physical	28514442
PTPRD_HUMAN	PTPRD	physical	28514442
PK3CB_HUMAN	PIK3CB	physical	28514442
P85B_HUMAN	PIK3R2	physical	28514442
NFRKB_HUMAN	NFRKB	physical	28514442
CAHD1_HUMAN	CACHD1	physical	28514442
MTMR1_HUMAN	MTMR1	physical	28514442
ZDHC9_HUMAN	ZDHHC9	physical	28514442
CUED1_HUMAN	CUEDC1	physical	28514442
RHEB_HUMAN	RHEB	physical	28514442
EHD4_HUMAN	EHD4	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.