| UniProt ID | NU107_MOUSE | |
|---|---|---|
| UniProt AC | Q8BH74 | |
| Protein Name | Nuclear pore complex protein Nup107 | |
| Gene Name | Nup107 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 926 | |
| Subcellular Localization | Nucleus membrane . Nucleus, nuclear pore complex . Chromosome, centromere, kinetochore . Located on both the cytoplasmic and nuclear sides of the NPC core structure. During mitosis, localizes to the kinetochores. Dissociates from the dissasembled NPC | |
| Protein Description | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.. | |
| Protein Sequence | MDRSGFGGMSSPVIRDAEVTRTARKHSAHKRVLIQANQEDNFGTATPRSQIIPRTPSSFRQPFVTPSSRSLLRHPDISYILGTEGRSPRHTQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGLYTNTEHHSMTEDVNLSTVMLREDDPGEAASMSMFSDFLHSFLKHSSTTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLEEENMFAIAGINASEKMVVETLFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSHMGSTRPLVTELDPDAPIRQKLPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIRTSVMTQDDSEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDVDGLMDEFSKWLSKSGSSLPGHLLRFMTHLILFLRTLGLQTKEEVSIEVLKTYIQLLISEKHTSLIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENICKKDNGEFSHHDLAPSLDTGTTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKPTLLSQATFTEKVAYEHREKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEDDPERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDRSGFGG -------CCCCCCCC | 9.73 | - | |
| 4 | Phosphorylation | ----MDRSGFGGMSS ----CCCCCCCCCCC | 33.92 | 23527152 | |
| 10 | Phosphorylation | RSGFGGMSSPVIRDA CCCCCCCCCCCCCCH | 34.46 | 23684622 | |
| 11 | Phosphorylation | SGFGGMSSPVIRDAE CCCCCCCCCCCCCHH | 17.81 | 23527152 | |
| 20 | Phosphorylation | VIRDAEVTRTARKHS CCCCHHHHHHHHHCC | 17.51 | 23984901 | |
| 27 | Phosphorylation | TRTARKHSAHKRVLI HHHHHHCCCCCEEEE | 34.79 | 22067460 | |
| 44 | Phosphorylation | NQEDNFGTATPRSQI CCCCCCCCCCCHHHC | 24.18 | 25619855 | |
| 46 | Phosphorylation | EDNFGTATPRSQIIP CCCCCCCCCHHHCCC | 21.05 | 27087446 | |
| 49 | Phosphorylation | FGTATPRSQIIPRTP CCCCCCHHHCCCCCC | 27.25 | 29514104 | |
| 55 | Phosphorylation | RSQIIPRTPSSFRQP HHHCCCCCCCCCCCC | 23.36 | 25266776 | |
| 57 | Phosphorylation | QIIPRTPSSFRQPFV HCCCCCCCCCCCCCC | 41.31 | 27600695 | |
| 58 | Phosphorylation | IIPRTPSSFRQPFVT CCCCCCCCCCCCCCC | 26.17 | 27600695 | |
| 60 | Methylation | PRTPSSFRQPFVTPS CCCCCCCCCCCCCCC | 45.25 | 24129315 | |
| 60 | Asymmetric dimethylarginine | PRTPSSFRQPFVTPS CCCCCCCCCCCCCCC | 45.25 | - | |
| 65 | Phosphorylation | SFRQPFVTPSSRSLL CCCCCCCCCCHHHHH | 20.17 | 22067460 | |
| 67 | Phosphorylation | RQPFVTPSSRSLLRH CCCCCCCCHHHHHHC | 29.08 | 22067460 | |
| 68 | Phosphorylation | QPFVTPSSRSLLRHP CCCCCCCHHHHHHCC | 27.39 | 22006019 | |
| 69 | Methylation | PFVTPSSRSLLRHPD CCCCCCHHHHHHCCC | 35.34 | 24129315 | |
| 70 | Phosphorylation | FVTPSSRSLLRHPDI CCCCCHHHHHHCCCC | 33.43 | - | |
| 78 | Phosphorylation | LLRHPDISYILGTEG HHHCCCCEEEECCCC | 17.32 | 25619855 | |
| 79 | Phosphorylation | LRHPDISYILGTEGR HHCCCCEEEECCCCC | 10.66 | 25619855 | |
| 83 | Phosphorylation | DISYILGTEGRSPRH CCEEEECCCCCCCCC | 31.64 | 25521595 | |
| 87 | Phosphorylation | ILGTEGRSPRHTQSS EECCCCCCCCCCCCC | 36.82 | 25521595 | |
| 101 | Ubiquitination | SGYLGNLSMVTNLDD CCCCCCEEEEECCCC | 18.40 | 27667366 | |
| 123 | Phosphorylation | SSQRLGLYTNTEHHS HHHHCCCEECCCCCC | 8.99 | 21183079 | |
| 124 | Phosphorylation | SQRLGLYTNTEHHSM HHHCCCEECCCCCCC | 40.48 | 21183079 | |
| 130 | Phosphorylation | YTNTEHHSMTEDVNL EECCCCCCCCCCCCC | 29.34 | 19060867 | |
| 132 | Phosphorylation | NTEHHSMTEDVNLST CCCCCCCCCCCCCCE | 31.86 | 19060867 | |
| 138 | Phosphorylation | MTEDVNLSTVMLRED CCCCCCCCEEEEECC | 17.47 | 26370283 | |
| 202 | Ubiquitination | RATPGLQKFSKTASM HCCCCHHHHHHHHHH | 57.56 | 27667366 | |
| 233 | Phosphorylation | LYRDRIQSSLEEENM HHHHHHHHCCHHCCC | 34.22 | 25521595 | |
| 234 | Phosphorylation | YRDRIQSSLEEENMF HHHHHHHCCHHCCCH | 24.35 | 25521595 | |
| 312 | Phosphorylation | LKQRQLLSHMGSTRP HHHHHHHHCCCCCCC | 21.74 | 22871156 | |
| 316 | Phosphorylation | QLLSHMGSTRPLVTE HHHHCCCCCCCCEEE | 17.42 | 22871156 | |
| 423 | Acetylation | AEDELFNKYERAIYA HHHHHHHHHHHHHHH | 40.95 | 22826441 | |
| 476 | Phosphorylation | SVMTQDDSEELPREY HCCCCCCCCCCCHHH | 41.06 | 22067460 | |
| 570 | Phosphorylation | LQTKEEVSIEVLKTY CCCCCCHHHHHHHHH | 19.13 | 28542873 | |
| 638 | Ubiquitination | LDVATITKTVVENIC CCHHHHHHHHHHHHH | 35.16 | - | |
| 653 | Phosphorylation | KKDNGEFSHHDLAPS CCCCCCCCCCCCCCC | 18.66 | 22067460 | |
| 660 | Phosphorylation | SHHDLAPSLDTGTTE CCCCCCCCCCCCCCH | 33.02 | 26370283 | |
| 784 | Phosphorylation | LLSQATFTEKVAYEH CHHCCCHHHHHHHHH | 30.46 | 22067460 | |
| 815 | Ubiquitination | DALTADVKEKMYNVL HHHCHHHHHHHCCEE | 52.76 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NU107_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NU107_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NU107_MOUSE !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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