KARG_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KARG_DROME
• UniProt AC: P48610
• Protein Name: Arginine kinase
• Gene Name: Argk
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 356
• Protein Sequence: MVDAAVLAKLEEGYAKLAASDSKSLLKKYLTKEVFDNLKNKVTPTFKSTLLDVIQSGLENHDSGVGIYAPDAEAYTVFADLFDPIIEDYHGGFKKTDKHPASNFGDVSTFGNVDPTNEYVISTRVRCGRSMQGYPFNPCLTEAQYKEMESKVSSTLSGLEGELKGKFYPLTGMEKAVQQQLIDDHFLFKEGDRFLQAANACRFWPSGRGIYHNDAKTFLVWCNEEDHLRIISMQQGGDLGQIYKRLVTAVNEIEKRVPFSHDDRLGFLTFCPTNLGTTIRASVHIKVPKLASNKAKLEEVAAKYNLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFEAVKEMYDGITELIKLEKSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
150	Phosphorylation	AQYKEMESKVSSTLS HHHHHHHHHHHHHHH	36.73	27794539
153	Phosphorylation	KEMESKVSSTLSGLE HHHHHHHHHHHHHHH	22.72	27794539
154	Phosphorylation	EMESKVSSTLSGLEG HHHHHHHHHHHHHHC	36.03	27794539
157	Phosphorylation	SKVSSTLSGLEGELK HHHHHHHHHHHCHHC	41.23	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KARG_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KARG_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KARG_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYSP1_DROME	Prm	physical	22036573
MYSP2_DROME	Prm	physical	22036573
MYSA_DROME	Mhc	physical	22036573
TPM2_DROME	Tm2	physical	22036573
GPDA_DROME	Gpdh	physical	22036573
TNNT_DROME	up	physical	22036573
MLC1_DROME	Mlc1	physical	22036573
ACTN_DROME	Actn	physical	22036573
MLR_DROME	Mlc2	physical	22036573
APLP_DROME	Rfabg	physical	22036573
TNNI_DROME	wupA	physical	22036573
LSP2_DROME	Lsp2	physical	22036573
VIT3_DROME	Yp3	physical	22036573
TNNC1_DROME	TpnC41C	physical	22036573
PGK_DROME	Pgk	physical	22036573
PYG_DROME	GlyP	physical	22036573
OB56D_DROME	Obp56d	physical	22036573
VIT2_DROME	Yp2	physical	22036573
CYC2_DROME	Cyt-c-p	physical	22036573
ENO_DROME	Eno	physical	22036573
NPLP2_DROME	Nplp2	physical	22036573
VIT1_DROME	Yp1	physical	22036573
ATP5J_DROME	ATPsyn-Cf6	physical	22036573
DHE3_DROME	Gdh	physical	22036573
G3P2_DROME	Gapdh2	physical	22036573
IDH3A_DROME	l(1)G0156	physical	22036573
RS27A_DROME	RpS27A	physical	24292889
CISY_DROME	kdn	physical	22036573

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.