FOXD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FOXD4_HUMAN
• UniProt AC: Q12950
• Protein Name: Forkhead box protein D4
• Gene Name: FOXD4
• Organism: Homo sapiens (Human).
• Sequence Length: 439
• Subcellular Localization: Nucleus.
• Protein Sequence: MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	PRAERLRSTPQRSLR CHHHHHHCCCCHHHC	49.37	-
393	Phosphorylation	GGHLSAASALLRYQA CHHHHHHHHHHHHHH	21.11	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FOXD4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FOXD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FOXD4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CRYAB_HUMAN	CRYAB	physical	25609649
GSTP1_HUMAN	GSTP1	physical	25609649
DMKN_HUMAN	DMKN	physical	25609649
RALY_HUMAN	RALY	physical	25609649
TRI29_HUMAN	TRIM29	physical	25609649
FX4L1_HUMAN	FOXD4L1	physical	25609649
RNH1_HUMAN	RNASEH1	physical	25609649
FOXD1_HUMAN	FOXD1	physical	25609649
S4A7_HUMAN	SLC4A7	physical	25609649
TACO1_HUMAN	TACO1	physical	25609649
IF2P_HUMAN	EIF5B	physical	25609649
FX4L1_HUMAN	FOXD4L1	physical	28514442
PDK2_HUMAN	PDK2	physical	28514442
PDK1_HUMAN	PDK1	physical	28514442
PP2AA_HUMAN	PPP2CA	physical	28514442
ZBTB9_HUMAN	ZBTB9	physical	28514442
PDK3_HUMAN	PDK3	physical	28514442
2ABD_HUMAN	PPP2R2D	physical	28514442
CHCH2_HUMAN	CHCHD2	physical	28514442
S4A7_HUMAN	SLC4A7	physical	28514442
FOXD2_HUMAN	FOXD2	physical	28514442
2AAB_HUMAN	PPP2R1B	physical	28514442
ODPX_HUMAN	PDHX	physical	28514442
SAHH3_HUMAN	AHCYL2	physical	28514442
2ABA_HUMAN	PPP2R2A	physical	28514442
PSMG4_HUMAN	PSMG4	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
ODPB_HUMAN	PDHB	physical	28514442
TTC19_HUMAN	TTC19	physical	28514442
GGPPS_HUMAN	GGPS1	physical	28514442
PP2AB_HUMAN	PPP2CB	physical	28514442
C1QBP_HUMAN	C1QBP	physical	28514442
2AAA_HUMAN	PPP2R1A	physical	28514442
ODP2_HUMAN	DLAT	physical	28514442
ODPA_HUMAN	PDHA1	physical	28514442
PRAME_HUMAN	PRAME	physical	28514442
K0232_HUMAN	KIAA0232	physical	28514442
SAHH2_HUMAN	AHCYL1	physical	28514442
BAG1_HUMAN	BAG1	physical	28514442
ANR52_HUMAN	ANKRD52	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.