FX4L1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FX4L1_HUMAN
• UniProt AC: Q9NU39
• Protein Name: Forkhead box protein D4-like 1
• Gene Name: FOXD4L1
• Organism: Homo sapiens (Human).
• Sequence Length: 408
• Subcellular Localization: Nucleus .
• Protein Sequence: MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQPSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	PRAERPRSTPQRSLR CCCCCCCCCCCCHHC	47.31	27251275
12	Phosphorylation	RAERPRSTPQRSLRD CCCCCCCCCCCHHCC	25.39	27251275
20	Phosphorylation	PQRSLRDSDGEDGKI CCCHHCCCCCCCCCE	40.87	30576142
110	Phosphorylation	RQPAKPPYSYIALIT CCCCCCCHHHHHHHH	23.72	29978859
111	Phosphorylation	QPAKPPYSYIALITM CCCCCCHHHHHHHHH	18.81	29978859
112	Phosphorylation	PAKPPYSYIALITMA CCCCCHHHHHHHHHH	5.60	29978859
117	Phosphorylation	YSYIALITMAILQSP HHHHHHHHHHHHCCC	11.03	29978859
123	Phosphorylation	ITMAILQSPHKRLTL HHHHHHCCCCCCEEH	26.06	29978859
138	Phosphorylation	SGICAFISGRFPYYR HHHHHHHHCCCHHHH	19.91	24719451
315	Phosphorylation	EEGKGLASPPGGGCI CCCCCCCCCCCCCCE	36.35	-
362	Phosphorylation	LQRPSSLSDNFAATA HCCCCCCCCCHHHHH	32.24	-
368	Phosphorylation	LSDNFAATAAASGGG CCCCHHHHHHHCCCH	17.25	-
382	Phosphorylation	GLRQRLRSHQGRGAG HHHHHHHHCCCCCCC	25.42	-
402	Phosphorylation	RVGAAAVSGGGRGL- CCHHHHHCCCCCCC-	27.30	22985185
406	Methylation	AAVSGGGRGL----- HHHCCCCCCC-----	46.65	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FX4L1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FX4L1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FX4L1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FX4L1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.