CLC3A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLC3A_HUMAN
• UniProt AC: O75596
• Protein Name: C-type lectin domain family 3 member A
• Gene Name: CLEC3A
• Organism: Homo sapiens (Human).
• Sequence Length: 197
• Subcellular Localization: Secreted .
• Protein Description: Promotes cell adhesion to laminin-332 and fibronectin..
• Protein Sequence: MAKNGLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGDLKTQIEKLWTEVNALKEIQALQTVCLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVNDFWLGINDMVTEGKFVDVNGIAISFLNWDRAQPNGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	VICILVITLLLDQTT HHHHHHHHHHHHCCC	12.13	22210691
25	Phosphorylation	DQTTSHTSRLKARKH HCCCCCHHHHHHHHH	30.14	-
53	Phosphorylation	TQIEKLWTEVNALKE HHHHHHHHHHHHHHH	40.26	28102081
79	Phosphorylation	TKVHKKCYLASEGLK CCCHHHHHHHHHHHH	17.74	28152594
82	Phosphorylation	HKKCYLASEGLKHFH HHHHHHHHHHHHHHH	29.60	28152594
108	Phosphorylation	ILVIPRNSDEINALQ EEEECCCHHHHHHHH	37.59	27251275
117	Phosphorylation	EINALQDYGKRSLPG HHHHHHHHHHCCCCC	16.16	27251275
173	Phosphorylation	NCVLFSQSAQGKWSD CEEEEECCCCCCCCH	22.74	24260401

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLC3A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLC3A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLC3A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RNH1_HUMAN	RNASEH1	physical	28514442
PHF10_HUMAN	PHF10	physical	28514442
YYAP1_HUMAN	YY1AP1	physical	28514442
ZN430_HUMAN	ZNF430	physical	28514442
CATIN_HUMAN	CACTIN	physical	28514442
RBM23_HUMAN	RBM23	physical	28514442
KBTB7_HUMAN	KBTBD7	physical	28514442
CTBL1_HUMAN	CTNNBL1	physical	28514442
LS14B_HUMAN	LSM14B	physical	28514442
C1QBP_HUMAN	C1QBP	physical	28514442
RBM27_HUMAN	RBM27	physical	28514442
KBTB6_HUMAN	KBTBD6	physical	28514442
ZN638_HUMAN	ZNF638	physical	28514442
ZN579_HUMAN	ZNF579	physical	28514442
RN220_HUMAN	RNF220	physical	28514442
ZZEF1_HUMAN	ZZEF1	physical	28514442
FAF1_HUMAN	FAF1	physical	28514442
RSPRY_HUMAN	RSPRY1	physical	28514442
PRC2A_HUMAN	PRRC2A	physical	28514442
ZFP91_HUMAN	ZFP91	physical	28514442
EI2BA_HUMAN	EIF2B1	physical	28514442
TF3C2_HUMAN	GTF3C2	physical	28514442
JUN_HUMAN	JUN	physical	28514442
RRP1_HUMAN	RRP1	physical	28514442
MRM3_HUMAN	RNMTL1	physical	28514442
INSR_HUMAN	INSR	physical	28514442
CLPX_HUMAN	CLPX	physical	28514442
RL36L_HUMAN	RPL36AL	physical	28514442
ATF6A_HUMAN	ATF6	physical	28514442
BAG1_HUMAN	BAG1	physical	28514442
HECD3_HUMAN	HECTD3	physical	28514442
ZN593_HUMAN	ZNF593	physical	28514442
LBR_HUMAN	LBR	physical	28514442
DHX57_HUMAN	DHX57	physical	28514442
ZMYM4_HUMAN	ZMYM4	physical	28514442
CLN5_HUMAN	CLN5	physical	28514442
WDR54_HUMAN	WDR54	physical	28514442
RBM26_HUMAN	RBM26	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.