CIAO1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CIAO1_YEAST
• UniProt AC: Q05583
• Protein Name: Cytosolic iron-sulfur protein assembly protein 1
• Gene Name: CIA1 {ECO:0000255|HAMAP-Rule:MF_03037}
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 330
• Subcellular Localization: Cytoplasm. Nucleus. Preferentially localized to the nucleus.
• Protein Description: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins..
• Protein Sequence: MASINLIKSLKLYKEKIWSFDFSQGILATGSTDRKIKLVSVKYDDFTLIDVLDETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRVWKYMGDDEDDQQEWVCEAILPDVHKRQVYNVAWGFNGLIASVGADGVLAVYEEVDGEWKVFAKRALCHGVYEINVVKWLELNGKTILATGGDDGIVNFWSLEKAA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
302	Ubiquitination	VYEINVVKWLELNGK EEEEEEEEEEEECCE	41.60	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CIAO1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CIAO1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CIAO1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MDY2_YEAST	MDY2	physical	11805837
RPN8_YEAST	RPN8	physical	11805837
MET18_YEAST	MET18	physical	11805837
DOG1_YEAST	DOG1	physical	11805837
UBP9_YEAST	UBP9	physical	11805837
YHS2_YEAST	CIA2	physical	10688190
NAR1_YEAST	NAR1	physical	16314508
YHS2_YEAST	CIA2	physical	11283351
MET18_YEAST	MET18	physical	22678362
CDC20_YEAST	CDC20	genetic	27708008
CH10_YEAST	HSP10	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
DPOD_YEAST	POL3	genetic	27708008
RRP42_YEAST	RRP42	genetic	27708008
GLE1_YEAST	GLE1	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
RSC8_YEAST	RSC8	genetic	27708008
NBP35_YEAST	NBP35	genetic	27708008
RRP41_YEAST	SKI6	genetic	27708008
YHS2_YEAST	CIA2	genetic	27708008
DNA2_YEAST	DNA2	genetic	27708008
CTF8_YEAST	CTF8	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
ATC7_YEAST	NEO1	genetic	27708008
DPB11_YEAST	DPB11	genetic	27708008
DPOD2_YEAST	POL31	genetic	27708008
ESS1_YEAST	ESS1	genetic	27708008
SSL1_YEAST	SSL1	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
PROF_YEAST	PFY1	genetic	27708008
NAB3_YEAST	NAB3	genetic	27708008
ARP7_YEAST	ARP7	genetic	27708008
SCS22_YEAST	SCS22	genetic	27708008
HMT1_YEAST	HMT1	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
DCC1_YEAST	DCC1	genetic	27708008
MGMT_YEAST	MGT1	genetic	27708008
MAF1_YEAST	MAF1	genetic	27708008
CHO2_YEAST	CHO2	genetic	27708008
TBP7_YEAST	YTA7	genetic	27708008
NPR3_YEAST	NPR3	genetic	27708008
ASF1_YEAST	ASF1	genetic	27708008
SWE1_YEAST	SWE1	genetic	27708008
DPOD3_YEAST	POL32	genetic	27708008
FEN1_YEAST	RAD27	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
RT109_YEAST	RTT109	genetic	27708008
ARP6_YEAST	ARP6	genetic	27708008
TOP3_YEAST	TOP3	genetic	27708008
MMS22_YEAST	MMS22	genetic	27708008
CTF18_YEAST	CTF18	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
MAS5_YEAST	YDJ1	genetic	27708008
RRP6_YEAST	RRP6	genetic	27708008
PET20_YEAST	PET20	genetic	27708008
CTF4_YEAST	CTF4	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.