ABDA_DROME - dbPTM
ABDA_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ABDA_DROME
UniProt AC P29555
Protein Name Homeobox protein abdominal-A
Gene Name abd-A
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 590
Subcellular Localization Nucleus .
Protein Description Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for segmental identity of the second through eighth abdominal segments. Once a pattern of abd-A expression is turned on in a given parasegment, it remains on the more posterior parasegment, so that the complex pattern of expression is built up in the successive parasegments. Appears to repress expression of Ubx whenever they appear in the same cell, but abd-A is repressed by Abd-B only in the eight and ninth abdominal segments..
Protein Sequence MSKFVFDSMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHHSIIAHNPGHLHHSVVGQNDLKLGLGMGVGVGVGGIGPGIGGGLGGNLGMMSALDKSNHDLLKAVSKVNS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ABDA_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ABDA_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ABDA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ABDA_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CCNE_DROMECycEgenetic
15580266
SPITZ_DROMEspigenetic
12050142
ELF1_DROMEgrhgenetic
16049114
HMPB_DROMEpbgenetic
16094438
HTH_DROMEhthgenetic
10395787
SUHW_DROMEsu(Hw)genetic
1983117
SUHW_DROMEsu(Hw)genetic
2575516
CAS_DROMEcasgenetic
18510932
EXD_DROMEexdphysical
10398683
EXD_DROMEexdphysical
21276241
MAD_DROMEMadphysical
25869471
SLP2_DROMEslp2physical
25869471
EYA_DROMEeyaphysical
25869471
TF2B_DROMETfIIBphysical
25869471
SALM_DROMEsalmphysical
25869471
SUH_DROMESu(H)physical
25869471
TSH_DROMEtshphysical
21276241
TSH_DROMEtshphysical
25869471
APTE_DROMEapphysical
25869471
MEF2_DROMEMef2physical
25869471
EVE_DROMEevephysical
25869471
MAM_DROMEmamphysical
25869471
TWIST_DROMEtwiphysical
25869471
DLL_DROMEDllphysical
25869471
KRUP_DROMEKrphysical
25869471
FOXF_DROMEbinphysical
25869471
FOXF_DROMEbinphysical
21276241
MED19_DROMEMED19physical
24786462
KNIR_DROMEkniphysical
25869471
POXM_DROMEPoxmphysical
25869471
7UP1_DROMEsvpphysical
25869471
7UP2_DROMEsvpphysical
25869471
EMS_DROMEemsphysical
25869471
SRP_DROMEsrpphysical
25869471
UBX_DROMEUbxphysical
21276241
TIN_DROMEtinphysical
25869471
BAGP_DROMEbapphysical
25869471
SLOU_DROMEslouphysical
25869471
PNT1_DROMEpntphysical
25869471
PNT2_DROMEpntphysical
25869471
MYOD_DROMEnauphysical
25869471
ZFH1_DROMEzfh1physical
25869471
PNR_DROMEpnrphysical
25869471
COLL_DROMEknphysical
25869471

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ABDA_DROME

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Related Literatures of Post-Translational Modification

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