KNIR_DROME - dbPTM
KNIR_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KNIR_DROME
UniProt AC P10734
Protein Name Zygotic gap protein knirps
Gene Name kni
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 429
Subcellular Localization Nucleus .
Protein Description Transcriptional repressor. Binds to multiple sites in the eve stripe 3 enhancer element. Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression..
Protein Sequence MNQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNVGMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSASSPVGSPHTPGFGDMAAHLHHHHQQQQQQQVPRHPHMPLLGYPSYLSDPSAALPFFSMMGGVPHQSPFQLPPHLLFPGYHASAAAAAASAADAAYRQEMYKHRQSVDSVESQNRFSPASQPPVVQPTSSARQSPIDVCLEEDVHSVHSHQSSASLLHPIAIRATPTTPTSSSPLSFAAKMQSLSPVSVCSIGGETTSVVPVHPPTVSAQEGPMDLSMKTSRSSVHSFNDSGSEDQEVEVAPRRKFYQLEAECLTTSSSSSSHSAAHSPNTTTAHAEVKRQKLGGAEATHFGGFAVAHNAASAMRGIFVCV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of KNIR_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KNIR_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KNIR_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KNIR_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CTBP_DROMECtBPphysical
14605208
ROGDI_DROMErogdiphysical
14605208
EGFR_DROMEEgfrgenetic
1980740
RHOM_DROMErhogenetic
12466192
KNRL_DROMEknrlgenetic
11118880
KNRL_DROMEknrlgenetic
12466192
EGON_DROMEeggenetic
12466192
HUNB_DROMEhbgenetic
11518507
ASH2_DROMEash2genetic
15371308
GROU_DROMEgrogenetic
19805071
TBB2_DROMEbetaTub85Dphysical
25242320
CTBP_DROMECtBPphysical
9525852
GROU_DROMEgrophysical
19805071

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KNIR_DROME

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Related Literatures of Post-Translational Modification

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