| UniProt ID | COLL_DROME | |
|---|---|---|
| UniProt AC | P56721 | |
| Protein Name | Transcription factor collier | |
| Gene Name | kn | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 575 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment.. | |
| Protein Sequence | MEWGRKLYPSAVSGPRSAGGLMFGLPPTAAVDMNQPRGPMTSLKEEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPRSPGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGATAASAAVAATANGYAPAPNMGTLSSSPGSVFNSTSMSAVSSTWHQAFVQHHHAATAHPHHHYPHPHQPWHNPAVSAATAAAV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 351 | Phosphorylation | SHAIRVQTPPRHIPG HCCEEECCCCCCCCC | 32.19 | 22817900 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COLL_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of COLL_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COLL_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DNJC5_DROME | Csp | physical | 15710747 | |
| TNKS_DROME | Tnks | physical | 15710747 | |
| SCAL_DROME | sd | physical | 15710747 | |
| Y678_DROME | CG2678 | physical | 15710747 | |
| DDX51_DROME | Dbp73D | physical | 15710747 | |
| NU301_DROME | E(bx) | physical | 15710747 | |
| EVE_DROME | eve | physical | 15710747 | |
| FKB12_DROME | FK506-bp2 | physical | 15710747 | |
| POF_DROME | Pof | physical | 15710747 | |
| TUD_DROME | tud | physical | 15710747 | |
| UN119_DROME | unc-119 | physical | 15710747 | |
| DLT_DROME | dlt | physical | 15710747 | |
| VIR_DROME | vir | physical | 15710747 | |
| FUSED_DROME | fu | genetic | 10375526 | |
| ABRU_DROME | ab | genetic | 17825045 | |
| EGFR_DROME | Egfr | genetic | 1980740 | |
| OCAD1_DROME | asrij | genetic | 23972987 | |
| RAC1_DROME | Rac1 | genetic | 18093520 | |
| HH_DROME | hh | genetic | 10375526 | |
| SPAST_DROME | spas | genetic | 18093520 | |
| CUT_DROME | ct | genetic | 18093520 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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