dbPTM

DNJC5_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DNJC5_DROME
UniProt AC	Q03751
Protein Name	DnaJ homolog subfamily C member 5 homolog {ECO:0000250\|UniProtKB:Q9H3Z4}
Gene Name	Csp {ECO:0000312\|FlyBase:FBgn0004179}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	249
Subcellular Localization	Membrane Lipid-anchor.
Protein Description	May have an important role in presynaptic function..
Protein Sequence	MSAPGMDKRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSNQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITGCCCCCCCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAPVTSQPREQAGGQPVFAMPPPSGAVGVNPFTGAPVAANENTSLNTTEQTTYTPDMVNQKY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
12	Phosphorylation	GMDKRKLSTSGDSLY CCCCCCCCCCCCCHH	19429919
13	Phosphorylation	MDKRKLSTSGDSLYE CCCCCCCCCCCCHHH	19429919
14	Phosphorylation	DKRKLSTSGDSLYEI CCCCCCCCCCCHHHH	19429919
17	Phosphorylation	KLSTSGDSLYEILGL CCCCCCCCHHHHHCC	19429919
19	Phosphorylation	STSGDSLYEILGLPK CCCCCCHHHHHCCCC	28490779
43	Acetylation	TYRKLALKYHPDKNP HHHHHHHHHCCCCCC	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DNJC5_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DNJC5_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DNJC5_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSP7D_DROME	Hsc70-4	physical	11395008
HSP7D_DROME	Hsc70-4	genetic	11395008
STX1A_DROME	Syx1A	genetic	10575024

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DNJC5_DROME

Related Literatures of Post-Translational Modification