VRP1_SCHPO - dbPTM
VRP1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VRP1_SCHPO
UniProt AC Q9P6R1
Protein Name Verprolin {ECO:0000312|EMBL:CAB89884.1}
Gene Name vrp1 {ECO:0000312|EMBL:CAB89884.1}
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 309
Subcellular Localization Cytoplasm, cytoskeleton . Localized to patches at the tips of growing interphase cells. These patches form prior to patches of myo1, but in cells lacking myo1, they are less intense and may be short lived. Detected in the medial region of mitotic cel
Protein Description Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins possessing SH3 domains. Plays a role in actin patch assembly by enhancing the ability of myo1 to stimulate actin polymerization by the Arp2/3 complex..
Protein Sequence MAPAPPPPPPAPAPAAAAPAPPLMTGDRSALLNSIQKGKKLKKATTNDRSAPVVGGGVVGERKSNTPKSFAAPPVPTGAPSLPTSSNNTQQAEERPSMPALGGLFAGGMPKLRHIGKSSASAAPPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPVPPSSYVLQQRPNRVDDHGRFHFKDDSYLPIPHPFLGVPKVYRGGSGTTVPLNLSSF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
45PhosphorylationGKKLKKATTNDRSAP
CCCCCCCCCCCCCCC		34.7024763107
153PhosphorylationRPSIPPPSPASAPPI
CCCCCCCCCCCCCCC		38.5829996109
156PhosphorylationIPPPSPASAPPIPSK
CCCCCCCCCCCCCCC		44.7029996109
183PhosphorylationQPAAPVKSPPSAPSL
CCCCCCCCCCCCCCC		42.1327738172
214PhosphorylationSQAPVANTSSRPSSF
HHCCCCCCCCCCHHC		20.5221712547
215PhosphorylationQAPVANTSSRPSSFA
HCCCCCCCCCCHHCC		24.9421712547
220PhosphorylationNTSSRPSSFAPPAGH
CCCCCCHHCCCCCCC		28.2727738172
232PhosphorylationAGHAPNVTSESPKFP
CCCCCCCCCCCCCCC		33.1629996109
233PhosphorylationGHAPNVTSESPKFPN
CCCCCCCCCCCCCCC		31.6229996109
235PhosphorylationAPNVTSESPKFPNRG
CCCCCCCCCCCCCCC		32.9129996109
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VRP1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VRP1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VRP1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
WSP1_SCHPOwsp1physical
12939254
MYO1_SCHPOmyo1physical
16087707
WSP1_SCHPOwsp1physical
16087707
ASK1_SCHPOask1genetic
18818364
LSB5_SCHPOlsb5genetic
18818364
PPK29_SCHPOppk29genetic
18818364
YORN_SCHPOrnf10genetic
18818364
DENR_SCHPOSPBC16C6.05genetic
18818364
COPE_SCHPOsec28genetic
18818364
NGG1_SCHPOngg1genetic
18818364
SWD3_SCHPOswd3genetic
18818364
ELP1_SCHPOelp1genetic
18818364
SUM2_SCHPOsum2genetic
18818364
YJM5_SCHPOSPCC1020.05genetic
18818364
CAF1_SCHPOcaf1genetic
18818364
SET1_SCHPOset1genetic
18818364
CCR4_SCHPOccr4genetic
18818364
ARP6_SCHPOarp6genetic
18818364
ASF1_SCHPOcia1genetic
18818364
SVF1_SCHPOSPCC584.11cgenetic
22681890
ILVB_SCHPOilv1genetic
22681890
YI81_SCHPOSPAPJ695.01cgenetic
22681890
SEC7B_SCHPOsec72genetic
22681890
FRP2_SCHPOfrp2genetic
22681890
UBP11_SCHPOubp11genetic
22681890
YK82_SCHPObdf2genetic
22681890
MTO1_SCHPOSPBC30B4.06cgenetic
22681890
CHP1_SCHPOchp1genetic
22681890
YDA5_SCHPOSPAC1F12.05genetic
22681890
YGWH_SCHPOgmh4genetic
22681890
MU113_SCHPOmug113genetic
22681890
RTF_SCHPOrtf1genetic
22681890
GIT3_SCHPOgit3genetic
22681890
YIT2_SCHPOSPAC105.02cgenetic
22681890
POM1_SCHPOpom1genetic
22681890
ARP42_SCHPOarp42genetic
22681890
PPR8_SCHPOppr8genetic
22681890
TEA2_SCHPOtea2genetic
22681890
CAM2_SCHPOcam2genetic
22681890
RRG9_SCHPOrrg9genetic
22681890
SUMT_SCHPOSPCC1739.06cgenetic
22681890
GBB_SCHPOgit5genetic
22681890
YOOH_SCHPOSPBC887.17genetic
22681890
ING2_SCHPOpng2genetic
22681890
ADN1_SCHPOadn1genetic
22681890
YO48_SCHPOSPBC36B7.08cgenetic
22681890
RHO2_SCHPOrho2genetic
22681890
GSH0_SCHPOSPCC737.06cgenetic
22681890
RM01_SCHPOSPAC1610.02cgenetic
22681890
GAR2_SCHPOgar2genetic
22681890
YL39_SCHPOSPAC1071.09cgenetic
22681890
RL16B_SCHPOrpl1601genetic
22681890
PPK38_SCHPOppk38genetic
22681890
YQ9A_SCHPOSPCC18.10genetic
22681890
YORS_SCHPOstc1genetic
22681890
ALAT_SCHPOSPBC582.08genetic
22681890
YA99_SCHPOSPAC13G6.09genetic
22681890
TREA_SCHPOntp1genetic
22681890
YAS5_SCHPOmms1genetic
22681890
MID1_SCHPOmid1genetic
22681890
YFE6_SCHPOgmh5genetic
22681890
EHS1_SCHPOyam8genetic
22681890
AREH2_SCHPOare2genetic
22681890
RS8A_SCHPOrps801genetic
22681890
NAA38_SCHPOnaa38genetic
22681890
MET8_SCHPOSPAC4D7.06cgenetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VRP1_SCHPO

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory