TMA20_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMA20_YEAST
• UniProt AC: P89886
• Protein Name: Translation machinery-associated protein 20
• Gene Name: TMA20
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 181
• Subcellular Localization: Cytoplasm .
• Protein Description: Involved in translation..
• Protein Sequence: MFKKFTREDVHSRSKVKSSIQRTLKAKLVKQYPKIEDVIDELIPKKSQIELIKCEDKIQLYSVDGEVLFFQKFDELIPSLKLVHKFPEAYPTVQVDRGAIKFVLSGANIMCPGLTSAGADLPPAPGYEKGTIVVINAENKENALAIGELMMGTEEIKSVNKGHSIELIHHLGDPLWNFSVE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MFKKFTRE -------CCCCCCHH	11.37	22814378
32	Phosphorylation	KAKLVKQYPKIEDVI HHHHHHHCCCHHHHH	10.77	19795423
45	Acetylation	VIDELIPKKSQIELI HHHHHCCCHHHEEEE	59.05	24489116
47	Phosphorylation	DELIPKKSQIELIKC HHHCCCHHHEEEEEE	42.38	21440633
81	Ubiquitination	DELIPSLKLVHKFPE HHHHHHHCHHHCCCC	53.45	24961812
85	Ubiquitination	PSLKLVHKFPEAYPT HHHCHHHCCCCCCCE	55.95	23749301
85	Acetylation	PSLKLVHKFPEAYPT HHHCHHHCCCCCCCE	55.95	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMA20_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMA20_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMA20_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
T2EA_YEAST	TFA1	physical	11805826
DENR_YEAST	TMA22	physical	11805826
DENR_YEAST	TMA22	physical	16554755
RS3A2_YEAST	RPS1B	physical	16429126
RS3_YEAST	RPS3	physical	16429126
RS4A_YEAST	RPS4A	physical	16429126
RS4B_YEAST	RPS4A	physical	16429126
RS8A_YEAST	RPS8A	physical	16429126
RS8B_YEAST	RPS8A	physical	16429126
T2EA_YEAST	TFA1	physical	16429126
DENR_YEAST	TMA22	physical	16429126
DENR_YEAST	TMA22	physical	16702403
MNN10_YEAST	MNN10	genetic	17314980
SRB8_YEAST	SRB8	genetic	17314980
ETR1_YEAST	ETR1	genetic	20093466
EF1A_YEAST	TEF2	genetic	20093466
TMA64_YEAST	TMA64	genetic	20093466
RV167_YEAST	RVS167	genetic	20093466
RS23A_YEAST	RPS23A	genetic	20093466
RS23B_YEAST	RPS23A	genetic	20093466
PLMT_YEAST	OPI3	genetic	20093466
RL43A_YEAST	RPL43B	genetic	20093466
RL43B_YEAST	RPL43B	genetic	20093466
SAC1_YEAST	SAC1	genetic	20093466
RS21A_YEAST	RPS21A	genetic	20093466
RL37A_YEAST	RPL37A	genetic	20093466
RS28B_YEAST	RPS28B	genetic	20093466
VRP1_YEAST	VRP1	genetic	20093466
GBLP_YEAST	ASC1	genetic	20093466
OCA1_YEAST	OCA1	genetic	20093466
RS7B_YEAST	RPS7B	genetic	20093466
EOS1_YEAST	EOS1	genetic	20093466
MSB4_YEAST	MSB4	genetic	20093466
LIPA_YEAST	LIP5	genetic	20093466
RL22A_YEAST	RPL22A	genetic	27708008
ATC3_YEAST	DRS2	genetic	27708008
ETR1_YEAST	ETR1	genetic	27708008
TMA64_YEAST	TMA64	genetic	27708008
NUM1_YEAST	NUM1	genetic	27708008
MNN10_YEAST	MNN10	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
RS23A_YEAST	RPS23A	genetic	27708008
RS23B_YEAST	RPS23A	genetic	27708008
SNF6_YEAST	SNF6	genetic	27708008
THIK_YEAST	POT1	genetic	27708008
RL43A_YEAST	RPL43B	genetic	27708008
RL43B_YEAST	RPL43B	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
RS21A_YEAST	RPS21A	genetic	27708008
ALAM_YEAST	ALT1	genetic	27708008
RL37A_YEAST	RPL37A	genetic	27708008
RS28B_YEAST	RPS28B	genetic	27708008
RL9B_YEAST	RPL9B	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
RS7B_YEAST	RPS7B	genetic	27708008
MSB4_YEAST	MSB4	genetic	27708008
FABD_YEAST	MCT1	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
DENR_HUMAN	DENR	physical	27107014

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.