WBP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WBP1_HUMAN
• UniProt AC: Q96G27
• Protein Name: WW domain-binding protein 1
• Gene Name: WBP1
• Organism: Homo sapiens (Human).
• Sequence Length: 269
• Protein Sequence: MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLSTFKPPAYEDVVHRPGTPPPPYTVAPGRPLTASSEQTCCSSSSSCPAHFEGTNVEGVSSHQSAPPHQEGEPGAGVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDLEDYSPCALPPESVPQIFPMGLSSSEGDIP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
110	Phosphorylation	HGAGPFPTGSLLDLR CCCCCCCCCCCCHHH	39.52	24719451
112	Phosphorylation	AGPFPTGSLLDLRFL CCCCCCCCCCHHHHH	28.39	28348404
136	Phosphorylation	DVVHRPGTPPPPYTV CCCCCCCCCCCCCCC	34.99	-
209	Phosphorylation	SCRYRRLTGDSGIEL CCCCCCCCCCCCCEE	36.81	23401153
212	Phosphorylation	YRRLTGDSGIELCPC CCCCCCCCCCEEECC	42.91	29978859

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WBP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WBP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WBP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WWP1_HUMAN	WWP1	physical	9169421
WWP2_HUMAN	WWP2	physical	9169421
MAGI1_HUMAN	MAGI1	physical	9169421
CIAO1_HUMAN	CIAO1	physical	26186194
S39AB_HUMAN	SLC39A11	physical	26186194
AT12A_HUMAN	ATP12A	physical	26186194
AT2B4_HUMAN	ATP2B4	physical	26186194
METL9_HUMAN	METTL9	physical	26186194
PMGT2_HUMAN	POMGNT2	physical	26186194
MAN1_HUMAN	LEMD3	physical	26186194
HS12A_HUMAN	HSPA12A	physical	26186194
ZDH13_HUMAN	ZDHHC13	physical	26186194
NEDD4_HUMAN	NEDD4	physical	26186194
ITCH_HUMAN	ITCH	physical	26186194
NED4L_HUMAN	NEDD4L	physical	26186194
WWP1_HUMAN	WWP1	physical	26186194
SYVN1_HUMAN	SYVN1	physical	26186194
MMS19_HUMAN	MMS19	physical	26186194
WWOX_HUMAN	WWOX	physical	26186194
NDUB8_HUMAN	NDUFB8	physical	26186194
SPTC2_HUMAN	SPTLC2	physical	26186194
AN13A_HUMAN	ANKRD13A	physical	26186194
KCIP2_HUMAN	KCNIP2	physical	26186194
S39AA_HUMAN	SLC39A10	physical	26186194
EXTL3_HUMAN	EXTL3	physical	26186194
TMUB1_HUMAN	TMUB1	physical	26186194
ZDHC6_HUMAN	ZDHHC6	physical	26186194
HECW2_HUMAN	HECW2	physical	26186194
FBW1A_HUMAN	BTRC	physical	26186194
FBW1B_HUMAN	FBXW11	physical	26186194
ZNT7_HUMAN	SLC30A7	physical	26186194
S39A6_HUMAN	SLC39A6	physical	26186194
NDUC2_HUMAN	NDUFC2	physical	26186194
FA8A1_HUMAN	FAM8A1	physical	26186194
GLPK_HUMAN	GK	physical	26186194
COPA_HUMAN	COPA	physical	25894502
NED4L_HUMAN	NEDD4L	physical	28514442
WWOX_HUMAN	WWOX	physical	28514442
HECW2_HUMAN	HECW2	physical	28514442
ZDHC6_HUMAN	ZDHHC6	physical	28514442
KCIP2_HUMAN	KCNIP2	physical	28514442
NEDD4_HUMAN	NEDD4	physical	28514442
FBW1A_HUMAN	BTRC	physical	28514442
FBW1B_HUMAN	FBXW11	physical	28514442
S39AB_HUMAN	SLC39A11	physical	28514442
WWP1_HUMAN	WWP1	physical	28514442
MAN1_HUMAN	LEMD3	physical	28514442
NDUB8_HUMAN	NDUFB8	physical	28514442
ZDH13_HUMAN	ZDHHC13	physical	28514442
AT2B4_HUMAN	ATP2B4	physical	28514442
FA8A1_HUMAN	FAM8A1	physical	28514442
ITCH_HUMAN	ITCH	physical	28514442
AT12A_HUMAN	ATP12A	physical	28514442
EXTL3_HUMAN	EXTL3	physical	28514442
MMS19_HUMAN	MMS19	physical	28514442
NDUC2_HUMAN	NDUFC2	physical	28514442
HS12A_HUMAN	HSPA12A	physical	28514442
SYVN1_HUMAN	SYVN1	physical	28514442
ZNT7_HUMAN	SLC30A7	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.