dbPTM

SQT1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SQT1_YEAST
UniProt AC	P35184
Protein Name	Ribosome assembly protein SQT1
Gene Name	SQT1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	431
Subcellular Localization
Protein Description	May be involved in the late step of 60S ribosomal subunit assembly or modification in the cytoplasm..
Protein Sequence	MEPQEEFITTEEVEQEIVPTVEVEQDVPVDIEGENDDDDEMMNDDEEALEVDMSNNSLTYFDKHTDSVFAIGHHPNLPLVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLASQMQEVEEIVWLKTHPTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQDCSMGEFINTDKGENTLELVTCSLDSTIVAWNCFTGQQLFKITQAEIKGLEAPWISLSLAPETLTKGNSGVVACGSNNGLLAVINCNNGGAILHLSTVIELKPEQDELDASIESISWSSKFSLMAIGLVCGEILLYDTSAWRVRHKFVLEDSVTKLMFDNDDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFILLHPVANTGTEQKRKVITAGDEGVSLVFEVPN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
250	Ubiquitination	KITQAEIKGLEAPWI EEEHHHHCCCCCCEE	49.28	23749301
348	Acetylation	SAWRVRHKFVLEDSV CCCCEEEEEEECCCE	26.97	22865919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SQT1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SQT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SQT1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL10_YEAST	RPL10	physical	9271392
RPN5_YEAST	RPN5	physical	16554755
SEM1_YEAST	SEM1	physical	16554755
RPN11_YEAST	RPN11	physical	16554755
RL10_YEAST	RPL10	physical	16554755
RPN8_YEAST	RPN8	physical	16554755
IF6_YEAST	TIF6	physical	18467557
RL10_YEAST	RPL10	physical	26750486
BLM10_YEAST	BLM10	genetic	27708008
COG3_YEAST	COG3	genetic	27708008
SHE1_YEAST	SHE1	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
IPT1_YEAST	IPT1	genetic	27708008
NUM1_YEAST	NUM1	genetic	27708008
SND1_YEAST	YDR186C	genetic	27708008
ESC2_YEAST	ESC2	genetic	27708008
GLRX2_YEAST	GRX2	genetic	27708008
CGR1_YEAST	CGR1	genetic	27708008
MMS2_YEAST	MMS2	genetic	27708008
ASK10_YEAST	ASK10	genetic	27708008
GEA1_YEAST	GEA1	genetic	27708008
FRMSR_YEAST	YKL069W	genetic	27708008
LDB18_YEAST	LDB18	genetic	27708008
CTL1_YEAST	CTL1	genetic	27708008
JNM1_YEAST	JNM1	genetic	27708008
PUR1_YEAST	ADE4	genetic	27708008
VAM3_YEAST	VAM3	genetic	27708008
SERC_YEAST	SER1	genetic	27708008
PEX27_YEAST	PEX27	genetic	27708008
POC4_YEAST	POC4	genetic	27708008
UBA3_YEAST	UBA3	genetic	27708008
THAP1_HUMAN	THAP1	physical	27107014
TRIM1_HUMAN	MID2	physical	27107014
BEND7_HUMAN	BEND7	physical	27107014
CEP55_HUMAN	CEP55	physical	27107014
PHC2_HUMAN	PHC2	physical	27107014
TRI27_HUMAN	TRIM27	physical	27107014
MDFI_HUMAN	MDFI	physical	27107014
TFCP2_HUMAN	TFCP2	physical	27107014
RBPMS_HUMAN	RBPMS	physical	27107014
GOGA2_HUMAN	GOLGA2	physical	27107014
BANP_HUMAN	BANP	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SQT1_YEAST

Related Literatures of Post-Translational Modification