GALD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GALD1_HUMAN
• UniProt AC: Q8NB37
• Protein Name: Glutamine amidotransferase-like class 1 domain-containing protein 1 {ECO:0000312|HGNC:HGNC:26616}
• Gene Name: GATD1 {ECO:0000312|HGNC:HGNC:26616}
• Organism: Homo sapiens (Human).
• Sequence Length: 220
• Subcellular Localization: Secreted .
• Protein Sequence: MASERLPNRPACLLVASGAAEGVSAQSFLHCFTMASTAFNLQVATPGGKAMEFVDVTESNARWVQDFRLKAYASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCATNEDRSWVFDSYSLTGPSVCELVRAPGFARLPLVVEDFVKDSGACFSASEPDAVHVVLDRHLVTGQNASSTVPAVQNLLFLCGSRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Sulfoxidation	ATPGGKAMEFVDVTE ECCCCEEEEEEECCC		21406390
70	Ubiquitination	WVQDFRLKAYASPAK EEHHHHEEEECCHHH		-
74	Phosphorylation	FRLKAYASPAKLESI HHEEEECCHHHEECC		30624053
77	Ubiquitination	KAYASPAKLESIDGA EEECCHHHEECCCCC		-
86	Phosphorylation	ESIDGARYHALLIPS ECCCCCEEEEEEECC		29496907
103	Phosphorylation	GALTDLASSGSLARI CHHHHHHHCCHHHHH		25693802
104	Phosphorylation	ALTDLASSGSLARIL HHHHHHHCCHHHHHH		25693802
106	Phosphorylation	TDLASSGSLARILQH HHHHHCCHHHHHHHH		25693802
109 (in isoform 4)	Phosphorylation	-		-
119	Ubiquitination	QHFHSESKPICAVGH HHHHCCCCCCCEECC		-
126 (in isoform 4)	Phosphorylation	-		-
128 (in isoform 4)	Phosphorylation	-		-
140	Phosphorylation	CATNEDRSWVFDSYS ECCCCCCCEEEECCC		24719451
147	Phosphorylation	SWVFDSYSLTGPSVC CEEEECCCCCCCCHH		24719451
152	Phosphorylation	SYSLTGPSVCELVRA CCCCCCCCHHHHHCC		24719451
174	Ubiquitination	LVVEDFVKDSGACFS EEEEHHHHCCCCCCC		-
189 (in isoform 2)	Ubiquitination	-		-
201	N-linked_Glycosylation	RHLVTGQNASSTVPA CCCCCCCCHHCHHHH		UniProtKB CARBOHYD
243 (in isoform 2)	Phosphorylation	-		25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GALD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GALD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GALD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PPCEL_HUMAN	PREPL	physical	28514442
HPS5_HUMAN	HPS5	physical	28514442
RTEL1_HUMAN	RTEL1	physical	28514442
FMN2_HUMAN	FMN2	physical	28514442
ITSN1_HUMAN	ITSN1	physical	28514442
PER1_HUMAN	PER1	physical	28514442
ERG7_HUMAN	LSS	physical	28514442
TRI65_HUMAN	TRIM65	physical	28514442
UBP54_HUMAN	USP54	physical	28514442
PRAME_HUMAN	PRAME	physical	28514442
EDRF1_HUMAN	EDRF1	physical	28514442
MKS1_HUMAN	MKS1	physical	28514442
PPM1A_HUMAN	PPM1A	physical	28514442
TBA1A_HUMAN	TUBA1A	physical	28514442
ANR40_HUMAN	ANKRD40	physical	28514442
TBA4A_HUMAN	TUBA4A	physical	28514442
TCPB_HUMAN	CCT2	physical	28514442
DTL_HUMAN	DTL	physical	28514442
SHPK_HUMAN	SHPK	physical	28514442
FANCJ_HUMAN	BRIP1	physical	28514442
ELP6_HUMAN	ELP6	physical	28514442
GNB1L_HUMAN	GNB1L	physical	28514442
ESPL1_HUMAN	ESPL1	physical	28514442
IF122_HUMAN	IFT122	physical	28514442
TCPD_HUMAN	CCT4	physical	28514442
CE034_HUMAN	C5orf34	physical	28514442
SMG8_HUMAN	SMG8	physical	28514442
KIF1A_HUMAN	KIF1A	physical	28514442
ZMYM2_HUMAN	ZMYM2	physical	28514442
P4K2B_HUMAN	PI4K2B	physical	28514442
GEMI5_HUMAN	GEMIN5	physical	28514442
2A5D_HUMAN	PPP2R5D	physical	28514442
TBB8_HUMAN	TUBB8	physical	28514442
TPRKB_HUMAN	TPRKB	physical	28514442
TBB3_HUMAN	TUBB3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.