GNB1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GNB1L_HUMAN
• UniProt AC: Q9BYB4
• Protein Name: Guanine nucleotide-binding protein subunit beta-like protein 1
• Gene Name: GNB1L
• Organism: Homo sapiens (Human).
• Sequence Length: 327
• Protein Sequence: MTAPCPPPPPDPQFVLRGTQSPVHALHFCEGAQAQGRPLLFSGSQSGLVHIWSLQTRRAVTTLDGHGGQCVTWLQTLPQGRQLLSQGRDLKLCLWDLAEGRSAVVDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDEVQILEMPSKTSVCALKPKADAKLGMPMCLRLWQADCSSRPLLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDWQQALQVRGTHELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAVQCVAFTADGLLAAGSKDQRISLWSLYPRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTAPCPPPP ------CCCCCCCCC	39.03	24719451
2	Acetylation	------MTAPCPPPP ------CCCCCCCCC	39.03	19413330
19	Phosphorylation	PQFVLRGTQSPVHAL CCCEEECCCCCCHHH	21.31	20873877
21	Phosphorylation	FVLRGTQSPVHALHF CEEECCCCCCHHHHC	28.82	20873877
91 (in isoform 2)	Ubiquitination	-	41.25	21906983
91 (in isoform 1)	Ubiquitination	-	41.25	21906983
91	Ubiquitination	LSQGRDLKLCLWDLA HHCCCCHHHHHHHHH	41.25	22817900
119	Phosphorylation	SVGFCRSSILAGGQP HCCCCHHHHHCCCCC	11.41	21712546
147	Phosphorylation	VQILEMPSKTSVCAL EEEEECCCCCCEEEE	47.45	30108239
148	Ubiquitination	QILEMPSKTSVCALK EEEECCCCCCEEEEC	38.66	21963094
155	Ubiquitination	KTSVCALKPKADAKL CCCEEEECCCHHCCC	26.41	29967540
157	Ubiquitination	SVCALKPKADAKLGM CEEEECCCHHCCCCC	58.26	29967540
161	Ubiquitination	LKPKADAKLGMPMCL ECCCHHCCCCCCHHH	46.23	-
218	Phosphorylation	VMDLDFDSQKARGIS CCCCCCCCCHHCCCC	33.31	-
220	Ubiquitination	DLDFDSQKARGISGS CCCCCCCHHCCCCCC	43.96	21963094
220	Acetylation	DLDFDSQKARGISGS CCCCCCCHHCCCCCC	43.96	25953088
266	Ubiquitination	VTIRPDRKILATAGW EEECCCCEEEEECCC	49.83	-
266	Malonylation	VTIRPDRKILATAGW EEECCCCEEEEECCC	49.83	26320211
284	Phosphorylation	IRVFHWRTMQPLAVL EEEEECCCCCHHHHH	18.24	22210691
313	Phosphorylation	DGLLAAGSKDQRISL CHHHHCCCCCCEEEE	28.47	22210691
324	Phosphorylation	RISLWSLYPRA---- EEEEEEECCCC----	5.78	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GNB1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GNB1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GNB1L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCPH_HUMAN	CCT7	physical	28514442
TCPG_HUMAN	CCT3	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.