CE034_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CE034_HUMAN
• UniProt AC: Q96MH7
• Protein Name: Uncharacterized protein C5orf34
• Gene Name: C5orf34
• Organism: Homo sapiens (Human).
• Sequence Length: 638
• Protein Sequence: MAAELRMILYEDDSVQVQYVDGSTLQLSPCGTEFLFEKSPPVSAHPLEQPERIRQRTHFVISTYREQLQRALDFRNSSATCPFLSETIIPSERKKHIFIDITEVRWPSLDTDGTMIYMESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVSQKSDSSAVLSETNNKAPKDKLVEKTGKICIRGNLPGQRLKNKENEFHCQIMKSKETLKKMSCVNGTEGREELPSPGTKHTCVYTWVKQCWSVAACPEEWKYPLSLALHFHNKISNMSKIDAHITQSRFLTSDISEERGKVVSVLPRALSLSCPVPHLHRWNFCDSLLQRQSDEYSYPELVKMVWYKGVTYRLTHQNMNSIEIYSGDGSVFKSEGAYFGNYFTYYSIQEGSGKREEKTYSVNNLPPDRPGSPFTVGSLIKQATRILQHCVKMRLSLSHNYRICCWKMVPGINDSNILPLVLKESLIPSVGRFLAYSDDKVHAIFLDGITLTLNWNFSSPIEKRQVNQGLNLGWCKLTFPDGQEQLIQIEHPEPYERYVTTVTSWCRRLTQTSPREMPTHSSSSVLQENWSVASELEKIQKFNLLLENSGILNQISNKKNEQQSFDHYKPGSSETLLGEVNENRVSIALKKTSEILHDIDCLLSNSKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Ubiquitination	PCGTEFLFEKSPPVS CCCCEEEEECCCCCC	15.68	22817900
40	Ubiquitination	EFLFEKSPPVSAHPL EEEEECCCCCCCCCC	44.36	21963094
53	Ubiquitination	PLEQPERIRQRTHFV CCCCHHHHHHHCCCH	4.14	21963094
56	Ubiquitination	QPERIRQRTHFVIST CHHHHHHHCCCHHHH	21.96	22817900
58	Ubiquitination	ERIRQRTHFVISTYR HHHHHHCCCHHHHHH	19.71	22817900
91	Phosphorylation	LSETIIPSERKKHIF CCCCCCCCCCCCEEE	39.36	24719451
150	Ubiquitination	FTVHFLCKVSQKSDS EEEEEEEEECCCCCC	47.25	22817900
152	Phosphorylation	VHFLCKVSQKSDSSA EEEEEEECCCCCCCC	19.86	30622161
154	Ubiquitination	FLCKVSQKSDSSAVL EEEEECCCCCCCCCH	49.04	21906983
155	Phosphorylation	LCKVSQKSDSSAVLS EEEECCCCCCCCCHH	34.78	30622161
156	Ubiquitination	CKVSQKSDSSAVLSE EEECCCCCCCCCHHH	54.36	21963094
157	Phosphorylation	KVSQKSDSSAVLSET EECCCCCCCCCHHHC	27.56	30622161
158	Phosphorylation	VSQKSDSSAVLSETN ECCCCCCCCCHHHCC	27.64	30622161
162	Phosphorylation	SDSSAVLSETNNKAP CCCCCCHHHCCCCCC	35.46	30622161
164	Phosphorylation	SSAVLSETNNKAPKD CCCCHHHCCCCCCHH	40.49	30622161
167	Ubiquitination	VLSETNNKAPKDKLV CHHHCCCCCCHHHHH	69.04	21963094
167	Methylation	VLSETNNKAPKDKLV CHHHCCCCCCHHHHH	69.04	-
170	Methylation	ETNNKAPKDKLVEKT HCCCCCCHHHHHHHC	72.81	-
170	Ubiquitination	ETNNKAPKDKLVEKT HCCCCCCHHHHHHHC	72.81	22817900
172	Ubiquitination	NNKAPKDKLVEKTGK CCCCCHHHHHHHCCC	61.63	22817900
177	Ubiquitination	KDKLVEKTGKICIRG HHHHHHHCCCEEECC	30.15	22817900
179	Ubiquitination	KLVEKTGKICIRGNL HHHHHCCCEEECCCC	39.37	29967540
192	Ubiquitination	NLPGQRLKNKENEFH CCCCHHHCCCCCHHH	69.07	-
218	Phosphorylation	KMSCVNGTEGREELP HHCCCCCCCCCCCCC	30.02	28555341
219	Ubiquitination	MSCVNGTEGREELPS HCCCCCCCCCCCCCC	58.62	21963094
224	Ubiquitination	GTEGREELPSPGTKH CCCCCCCCCCCCCCE	4.33	22817900
226	Phosphorylation	EGREELPSPGTKHTC CCCCCCCCCCCCEEE	48.89	28674419
230	Ubiquitination	ELPSPGTKHTCVYTW CCCCCCCCEEEEEEE	42.71	29967540
270	Ubiquitination	NKISNMSKIDAHITQ HHHCCHHHHCHHHCH	33.56	21963094
286	Phosphorylation	RFLTSDISEERGKVV HCCCCCCCHHHCCEE	38.09	-
291	Ubiquitination	DISEERGKVVSVLPR CCCHHHCCEEEEHHH	45.76	22817900
297	Ubiquitination	GKVVSVLPRALSLSC CCEEEEHHHHHHCCC	19.83	21963094
323	Ubiquitination	DSLLQRQSDEYSYPE HHHHHHCCCCCCHHH	34.30	21963094
333	Ubiquitination	YSYPELVKMVWYKGV CCHHHHHHHHHHCCC	40.12	21963094
338	Ubiquitination	LVKMVWYKGVTYRLT HHHHHHHCCCEEEEE	31.06	22817900
339	Ubiquitination	VKMVWYKGVTYRLTH HHHHHHCCCEEEEEC	10.99	21987572
360	Phosphorylation	EIYSGDGSVFKSEGA EEEECCCCEEEEECC	29.17	22210691
392	Ubiquitination	REEKTYSVNNLPPDR CEECEEECCCCCCCC	3.76	21963094
402	Phosphorylation	LPPDRPGSPFTVGSL CCCCCCCCCCCHHHH	21.37	28555341
408	Phosphorylation	GSPFTVGSLIKQATR CCCCCHHHHHHHHHH	23.68	24719451
411	Ubiquitination	FTVGSLIKQATRILQ CCHHHHHHHHHHHHH	38.89	21963094
426	Phosphorylation	HCVKMRLSLSHNYRI HHHHHHHHCCCCEEE	19.91	28555341
437	Ubiquitination	NYRICCWKMVPGIND CEEEEEEEECCCCCC	18.99	21963094
445	Phosphorylation	MVPGINDSNILPLVL ECCCCCCCCHHHHHH	22.68	-
453	Ubiquitination	NILPLVLKESLIPSV CHHHHHHHHHHCCCH	37.46	21987572
454	Ubiquitination	ILPLVLKESLIPSVG HHHHHHHHHHCCCHH	46.76	22817900
455	O-linked_Glycosylation	LPLVLKESLIPSVGR HHHHHHHHHCCCHHH	29.97	30379171
457	Ubiquitination	LVLKESLIPSVGRFL HHHHHHHCCCHHHHH	3.13	21963094
474	Ubiquitination	SDDKVHAIFLDGITL CCCCEEEEEECCEEE	1.81	21963094
475	Ubiquitination	DDKVHAIFLDGITLT CCCEEEEEECCEEEE	5.44	21963094
485	Ubiquitination	GITLTLNWNFSSPIE CEEEEEECCCCCCCC	15.45	21963094
506	Ubiquitination	GLNLGWCKLTFPDGQ CCCCEEEEEECCCCC	44.01	21963094
528	Phosphorylation	HPEPYERYVTTVTSW CCCCCHHHHHHHHHH	7.10	22210691
530	Phosphorylation	EPYERYVTTVTSWCR CCCHHHHHHHHHHHH	13.45	22210691
531	Phosphorylation	PYERYVTTVTSWCRR CCHHHHHHHHHHHHH	16.25	22210691
540	Phosphorylation	TSWCRRLTQTSPREM HHHHHHHCCCCCCCC	28.17	24425749
542	Phosphorylation	WCRRLTQTSPREMPT HHHHHCCCCCCCCCC	35.15	24425749
568	Ubiquitination	SVASELEKIQKFNLL HHHHHHHHHHHHHHH	64.16	22817900
571	Ubiquitination	SELEKIQKFNLLLEN HHHHHHHHHHHHHHC	39.43	21963094
588	Ubiquitination	ILNQISNKKNEQQSF HHHHHCCCCCCCCCC	50.62	21906983
589	Ubiquitination	LNQISNKKNEQQSFD HHHHCCCCCCCCCCC	70.71	21963094
598	Phosphorylation	EQQSFDHYKPGSSET CCCCCCCCCCCCCHH	22.26	28555341
599	Ubiquitination	QQSFDHYKPGSSETL CCCCCCCCCCCCHHE	39.21	21963094
603	Phosphorylation	DHYKPGSSETLLGEV CCCCCCCCHHEEEEE	40.28	28555341
616	Phosphorylation	EVNENRVSIALKKTS EECCCCEEEEEEHHH	10.02	30576142
621	Ubiquitination	RVSIALKKTSEILHD CEEEEEEHHHHHHHH	59.12	29967540
637	Ubiquitination	DCLLSNSKK------ HHHHHCCCC------	67.75	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CE034_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CE034_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CE034_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CE034_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.