F234B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F234B_HUMAN
• UniProt AC: A2RU67
• Protein Name: Protein FAM234B
• Gene Name: FAM234B {ECO:0000312|HGNC:HGNC:29288}
• Organism: Homo sapiens (Human).
• Sequence Length: 622
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQKNGGVKNGKSPLGEAPEPDSDAEVAEAAKPHLSEVTTEGYPSEPLGGLEQKAASSLVSYVRTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNGDGLRDVLLSFVMSRNGSAVGVSRPAANLVCLSGMNGSTLWSSLLPEEARDITCLELMPGSLAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGNPVGRPVKYNIVGVGNLIGPQVYITTNGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSDGVELLQMVKAPDSNCSNLLITTRQSLVLLRGQNLTPYWALRLQGLRSQPTPGYFTDDQTLDFLLQIQDGVGMKKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSVFLFWAEGLSAASPNSDIILGTEPPSLHHLYLLHPAFPSILLDLANTTGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAALVVSKLSLRWALMEGQMAQLQESTPKIGRGELRRFLSRIKFVEAPYEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MATVLSRALK -----CHHHHHHHHC		26074081
6	Phosphorylation	--MATVLSRALKLPG --CHHHHHHHHCCCC		26074081
16	Phosphorylation	LKLPGKKSPDLGEYD HCCCCCCCCCCCCCC		21712546
22	Phosphorylation	KSPDLGEYDPLTQAD CCCCCCCCCCCCCCC		21082442
26	Phosphorylation	LGEYDPLTQADSDES CCCCCCCCCCCCCCC		28102081
30	Phosphorylation	DPLTQADSDESEDDL CCCCCCCCCCCCCCE		26503892
33	Phosphorylation	TQADSDESEDDLVLN CCCCCCCCCCCEEEE		26503892
52	Phosphorylation	GGVKNGKSPLGEAPE CCCCCCCCCCCCCCC		25159151
62	Phosphorylation	GEAPEPDSDAEVAEA CCCCCCCCHHHHHHH		29255136
66	Ubiquitination	EPDSDAEVAEAAKPH CCCCHHHHHHHHCCC		22817900
71	Ubiquitination	AEVAEAAKPHLSEVT HHHHHHHCCCHHCCC		21906983
75	Phosphorylation	EAAKPHLSEVTTEGY HHHCCCHHCCCCCCC		30175587
78	Phosphorylation	KPHLSEVTTEGYPSE CCCHHCCCCCCCCCC		30576142
79	Phosphorylation	PHLSEVTTEGYPSEP CCHHCCCCCCCCCCC		30175587
82	Phosphorylation	SEVTTEGYPSEPLGG HCCCCCCCCCCCCCC		29978859
84	Phosphorylation	VTTEGYPSEPLGGLE CCCCCCCCCCCCCHH		29978859
149	Phosphorylation	SQGGGDLSPLELADV CCCCCCCCCHHHHCC		26714015
237	N-linked_Glycosylation	HKMLSAFNATSGKAI HHHHHHHCCCCCCEE		19349973
488	Phosphorylation	PATSAVTSDQKSVFL CCCCCCCCCCCEEEE		-
581	Phosphorylation	ALVVSKLSLRWALME HHHHHHHHHHHHHHH		20068231
597	Phosphorylation	QMAQLQESTPKIGRG HHHHHHHCCCCCCHH		20068231
598	Phosphorylation	MAQLQESTPKIGRGE HHHHHHCCCCCCHHH		20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F234B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F234B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F234B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DEP1A_HUMAN	DEPDC1	physical	28514442
ABCD4_HUMAN	ABCD4	physical	28514442
FRMD5_HUMAN	FRMD5	physical	28514442
S2551_HUMAN	SLC25A51	physical	28514442
TM214_HUMAN	TMEM214	physical	28514442
HIP1R_HUMAN	HIP1R	physical	28514442
NRSN2_HUMAN	NRSN2	physical	28514442
TRI13_HUMAN	TRIM13	physical	28514442
PX11B_HUMAN	PEX11B	physical	28514442
ORC5_HUMAN	ORC5	physical	28514442
MAN1_HUMAN	LEMD3	physical	28514442
SPDLY_HUMAN	SPDL1	physical	28514442
HERC5_HUMAN	HERC5	physical	28514442
LAP4A_HUMAN	LAPTM4A	physical	28514442
PEX16_HUMAN	PEX16	physical	28514442
PDS5B_HUMAN	PDS5B	physical	28514442
CKAP5_HUMAN	CKAP5	physical	28514442
B4GT5_HUMAN	B4GALT5	physical	28514442
S47A1_HUMAN	SLC47A1	physical	28514442
HBB_HUMAN	HBB	physical	28514442
SPAG5_HUMAN	SPAG5	physical	28514442
DHRS7_HUMAN	DHRS7	physical	28514442
RRP1_HUMAN	RRP1	physical	28514442
ADPGK_HUMAN	ADPGK	physical	28514442
TM245_HUMAN	TMEM245	physical	28514442
TNPO2_HUMAN	TNPO2	physical	28514442
CCNB2_HUMAN	CCNB2	physical	28514442
TBRG4_HUMAN	TBRG4	physical	28514442
TMX4_HUMAN	TMX4	physical	28514442
B4GT1_HUMAN	B4GALT1	physical	28514442
PTN1_HUMAN	PTPN1	physical	28514442
ARV1_HUMAN	ARV1	physical	28514442
TNFL9_HUMAN	TNFSF9	physical	28514442
UBE3C_HUMAN	UBE3C	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.