| UniProt ID | ARV1_HUMAN | |
|---|---|---|
| UniProt AC | Q9H2C2 | |
| Protein Name | Protein ARV1 | |
| Gene Name | ARV1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 271 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis. [PubMed: 11063737] | |
| Protein Sequence | MGNGGRSGLQQGKGNVDGVAATPTAASASCQYRCIECNQEAKELYRDYNHGVLKITICKSCQKPVDKYIEYDPVIILINAILCKAQAYRHILFNTQINIHGKLCIFCLLCEAYLRWWQLQDSNQNTAPDDLIRYAKEWDFYRMFAIAALEQTAYFIGIFTFLWVERPMTAKKKPNFILLLKALLLSSYGKLLLIPAVIWEHDYTSVCLKLIKVFVLTSNFQAIRVTLNINRKLSFLAVLSGLLLESIMVYFFQSMEWDVGSDYAIFKSQDF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Ubiquitination | RSGLQQGKGNVDGVA CCCCCCCCCCCCCEE | 42.87 | - | |
| 22 | Phosphorylation | NVDGVAATPTAASAS CCCCEEECCCCHHHC | 16.07 | 25159151 | |
| 24 | Phosphorylation | DGVAATPTAASASCQ CCEEECCCCHHHCCC | 30.42 | 29978859 | |
| 27 | Phosphorylation | AATPTAASASCQYRC EECCCCHHHCCCEEE | 20.46 | 30631047 | |
| 42 | Ubiquitination | IECNQEAKELYRDYN ECCCHHHHHHHHHCC | 47.72 | - | |
| 59 | Ubiquitination | VLKITICKSCQKPVD EEEEEEEHHCCCCCH | 50.87 | - | |
| 136 | Ubiquitination | DDLIRYAKEWDFYRM HHHHHHHHHCCHHHH | 50.86 | 21890473 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARV1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARV1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARV1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CREB1_HUMAN | CREB1 | physical | 26186194 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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