NRSN2_HUMAN - dbPTM
NRSN2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NRSN2_HUMAN
UniProt AC Q9GZP1
Protein Name Neurensin-2
Gene Name NRSN2
Organism Homo sapiens (Human).
Sequence Length 204
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description May play a role in maintenance and/or transport of vesicles..
Protein Sequence MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSLCWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGTALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQSWFSPPASPFGQSSVQTIQPKRDS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMMPSCNRSCSCSRGP
CCCCCCCCCCCCCCC
9.0823312004
10PhosphorylationPSCNRSCSCSRGPSV
CCCCCCCCCCCCCCC
19.1727422710
12PhosphorylationCNRSCSCSRGPSVED
CCCCCCCCCCCCCCC
24.7923312004
16PhosphorylationCSCSRGPSVEDGKWY
CCCCCCCCCCCCCEE
40.7523312004
21UbiquitinationGPSVEDGKWYGVRSY
CCCCCCCCEEEHHHH
49.9523000965
68PhosphorylationCWKISLSSGTLLLLL
HHEEECCHHHHHHHH
40.8826437602
70PhosphorylationKISLSSGTLLLLLGV
EEECCHHHHHHHHHH
19.0426437602
81PhosphorylationLLGVAALTTGYAVPP
HHHHHHHHCCCCCCC
17.2826437602
113UbiquitinationADYNQALGTCRLAGT
CCHHHHHHHHHHHHH
26.2821890473
157PhosphorylationPLDPEADSHVEVFGD
CCCCCCCCCEEEECC
36.1630266825
171PhosphorylationDEPEQQLSPIFRNAS
CCHHHHHCCCCCCCC
16.1830266825
178PhosphorylationSPIFRNASGQSWFSP
CCCCCCCCCCCCCCC
40.7029978859
181PhosphorylationFRNASGQSWFSPPAS
CCCCCCCCCCCCCCC
33.3529978859
184PhosphorylationASGQSWFSPPASPFG
CCCCCCCCCCCCCCC
24.5825106551
188PhosphorylationSWFSPPASPFGQSSV
CCCCCCCCCCCCCCC
26.9125106551
193PhosphorylationPASPFGQSSVQTIQP
CCCCCCCCCCEECCC
32.6222199227
194PhosphorylationASPFGQSSVQTIQPK
CCCCCCCCCEECCCC
15.4522199227
197PhosphorylationFGQSSVQTIQPKRDS
CCCCCCEECCCCCCC
21.3029978859

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NRSN2_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NRSN2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NRSN2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZDH17_HUMANZDHHC17physical
26186194
FITM2_HUMANFITM2physical
28514442
ZDH17_HUMANZDHHC17physical
28514442

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NRSN2_HUMAN

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Related Literatures of Post-Translational Modification

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