CP070_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CP070_HUMAN
• UniProt AC: Q9BSU1
• Protein Name: UPF0183 protein C16orf70
• Gene Name: C16orf70
• Organism: Homo sapiens (Human).
• Sequence Length: 422
• Protein Sequence: MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	LEVVPERSLGNEQWE CEECCCCCCCCCCEE	38.68	-
149	Phosphorylation	SWTEAPKYEPNFAHG CCCCCCCCCCCCCCC	35.24	27642862
159	Phosphorylation	NFAHGLASLQIPHGA CCCCCCEECCCCCCC	26.33	28555341
172	Phosphorylation	GATVKRMYIYSGNSL CCEEEEEEEEECCCC	10.76	-
231	Ubiquitination	PGLLADAKMRVFERS CCHHHHHHHHHHCCC	27.99	-
231	Acetylation	PGLLADAKMRVFERS CCHHHHHHHHHHCCC	27.99	25953088
257	Ubiquitination	SMLGSPHKVFYKSED HHHCCCCEEEEECCC	37.11	-
261	Acetylation	SPHKVFYKSEDKMKI CCCEEEEECCCCCCC	35.58	25953088
270	Phosphorylation	EDKMKIHSPSPHKQV CCCCCCCCCCCCCCC	30.46	26425664
272	Phosphorylation	KMKIHSPSPHKQVPS CCCCCCCCCCCCCCC	42.52	26055452
275	Ubiquitination	IHSPSPHKQVPSKCN CCCCCCCCCCCCCCC	57.27	-
334	Acetylation	FKIPLAIKKENADGQ EECEEEEEEECCCCC	48.72	7709815
364	Ubiquitination	LLGHPVEKPVVLHRS HHCCCCCCCEEEECC	43.26	-
371	Phosphorylation	KPVVLHRSSSPNNTN CCEEEECCCCCCCCC	25.15	20873877
372	Phosphorylation	PVVLHRSSSPNNTNP CEEEECCCCCCCCCC	50.17	26657352
373	Phosphorylation	VVLHRSSSPNNTNPF EEEECCCCCCCCCCC	32.66	26657352
377	Phosphorylation	RSSSPNNTNPFGSTF CCCCCCCCCCCCCCH	51.40	20873877

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CP070_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CP070_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CP070_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
SPB6_HUMAN	SERPINB6	physical	22939629
BCAS3_HUMAN	BCAS3	physical	26186194
AACT_HUMAN	SERPINA3	physical	26186194
NFH_HUMAN	NEFH	physical	26186194
NFL_HUMAN	NEFL	physical	26186194
CALL5_HUMAN	CALML5	physical	26186194
OCRL_HUMAN	OCRL	physical	26186194
DP13A_HUMAN	APPL1	physical	26186194
SBSN_HUMAN	SBSN	physical	26186194
CYTM_HUMAN	CST6	physical	26186194
NUP53_HUMAN	NUP35	physical	26186194
ANK3_HUMAN	ANK3	physical	26186194
GWL_HUMAN	MASTL	physical	26186194
SPB4_HUMAN	SERPINB4	physical	26186194
SPB3_HUMAN	SERPINB3	physical	26186194
TGM3_HUMAN	TGM3	physical	26186194
POMP_HUMAN	POMP	physical	26186194
POF1B_HUMAN	POF1B	physical	26186194
CALL3_HUMAN	CALML3	physical	26186194
PSMG2_HUMAN	PSMG2	physical	26186194
SAP3_HUMAN	GM2A	physical	26186194
FBX30_HUMAN	FBXO30	physical	26186194
LIPA1_HUMAN	PPFIA1	physical	26186194
S10A7_HUMAN	S100A7	physical	26186194
ZBT16_HUMAN	ZBTB16	physical	26186194
GWL_HUMAN	MASTL	physical	28514442
BCAS3_HUMAN	BCAS3	physical	28514442
ZBT16_HUMAN	ZBTB16	physical	28514442
LIPA1_HUMAN	PPFIA1	physical	28514442
POMP_HUMAN	POMP	physical	28514442
DP13A_HUMAN	APPL1	physical	28514442
POF1B_HUMAN	POF1B	physical	28514442
SPB4_HUMAN	SERPINB4	physical	28514442
FBX30_HUMAN	FBXO30	physical	28514442
PSMG2_HUMAN	PSMG2	physical	28514442
NUP53_HUMAN	NUP35	physical	28514442
NFH_HUMAN	NEFH	physical	28514442
AACT_HUMAN	SERPINA3	physical	28514442
OCRL_HUMAN	OCRL	physical	28514442
SPB3_HUMAN	SERPINB3	physical	28514442
TGM3_HUMAN	TGM3	physical	28514442
CYTM_HUMAN	CST6	physical	28514442
ANK3_HUMAN	ANK3	physical	28514442
S10A7_HUMAN	S100A7	physical	28514442
CALL5_HUMAN	CALML5	physical	28514442
CALL3_HUMAN	CALML3	physical	28514442
ZA2G_HUMAN	AZGP1	physical	28514442
SBSN_HUMAN	SBSN	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.