SSX2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SSX2_HUMAN
• UniProt AC: Q16385
• Protein Name: Protein SSX2
• Gene Name: SSX2
• Organism: Homo sapiens (Human).
• Sequence Length: 188
• Subcellular Localization: Nucleus.
• Protein Description: Could act as a modulator of transcription..
• Protein Sequence: MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	EWEKMKASEKIFYVY HHHHHHHHHHHEEHH	33.63	24719451
48	Phosphorylation	KASEKIFYVYMKRKY HHHHHHEEHHHHHHH	8.31	20049867
50	Phosphorylation	SEKIFYVYMKRKYEA HHHHEEHHHHHHHHH	5.87	20049867
108	Phosphorylation	FGRLQGISPKIMPKK HHHHCCCCCCCCCCC	27.28	22210691
110	Acetylation	RLQGISPKIMPKKPA HHCCCCCCCCCCCCC	44.86	26051181
123	Phosphorylation	PAEEGNDSEEVPEAS CCCCCCCCCCCCCCC	39.39	30278072
137	Acetylation	SGPQNDGKELCPPGK CCCCCCCCCCCCCCC	50.83	26051181
144	Acetylation	KELCPPGKPTTSEKI CCCCCCCCCCCHHHH	44.99	26051181
148	Phosphorylation	PPGKPTTSEKIHERS CCCCCCCHHHHHHHH	39.09	-
148 (in isoform 2)	Phosphorylation	-	39.09	25159151
177	Phosphorylation	ERKQLVIYEEISDPE HCCEEEEEEECCCCC	10.46	22210691
181	Phosphorylation	LVIYEEISDPEEDDE EEEEEECCCCCCCCC	50.85	30278072
185 (in isoform 2)	Phosphorylation	-	75.93	20860994
187 (in isoform 2)	Phosphorylation	-	67.78	16964243
188 (in isoform 2)	Phosphorylation	-	74.89	16964243
207	Phosphorylation	-------------------------- --------------------------		27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SSX2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SSX2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SSX2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RING2_HUMAN	RNF2	physical	19337376
SMCA2_HUMAN	SMARCA2	physical	11274403
ATF2_HUMAN	ATF2	physical	22439931
TLE1_HUMAN	TLE1	physical	22439931
SMCA2_HUMAN	SMARCA2	physical	22439931
SMCA5_HUMAN	SMARCA5	physical	22439931
HDAC1_HUMAN	HDAC1	physical	22439931
HDAC2_HUMAN	HDAC2	physical	22439931
EED_HUMAN	EED	physical	22439931
SUZ12_HUMAN	SUZ12	physical	22439931
EZH2_HUMAN	EZH2	physical	22439931
GO45_HUMAN	BLZF1	physical	25416956
TAXB1_HUMAN	TAX1BP1	physical	25416956
ZBED1_HUMAN	ZBED1	physical	25416956
AKAP9_HUMAN	AKAP9	physical	25416956
MAGC2_HUMAN	MAGEC2	physical	25416956
ZMIZ2_HUMAN	ZMIZ2	physical	25416956
SYCE1_HUMAN	SYCE1	physical	25416956
RAB3I_HUMAN	RAB3IP	physical	25416956
ADIP_HUMAN	SSX2IP	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
SSX3_HUMAN	SSX3	physical	26186194
SSX7_HUMAN	SSX7	physical	28514442
SSX3_HUMAN	SSX3	physical	28514442
SSX5_HUMAN	SSX5	physical	28514442
SESD1_HUMAN	SESTD1	physical	28514442
MET18_HUMAN	METTL18	physical	28514442
AKAP9_HUMAN	AKAP9	physical	28514442
DCAM_HUMAN	AMD1	physical	28514442
KIF3A_HUMAN	KIF3A	physical	28514442
CUL7_HUMAN	CUL7	physical	28514442
KAP3_HUMAN	PRKAR2B	physical	28514442
LYRM7_HUMAN	LYRM7	physical	28514442
CK5P2_HUMAN	CDK5RAP2	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.