LYRM7_HUMAN - dbPTM
LYRM7_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LYRM7_HUMAN
UniProt AC Q5U5X0
Protein Name Complex III assembly factor LYRM7
Gene Name LYRM7
Organism Homo sapiens (Human).
Sequence Length 104
Subcellular Localization Mitochondrion matrix .
Protein Description Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane..
Protein Sequence MGRAVKVLQLFKTLHRTRQQVFKNDARALEAARIKINEEFKNNKSETSSKKIEELMKIGSDVELLLRTSVIQGIHTDHNTLKLVPRKDLLVENVPYCDAPTQKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
6Ubiquitination--MGRAVKVLQLFKT
--CCHHHHHHHHHHH
35.9221890473
6Ubiquitination--MGRAVKVLQLFKT
--CCHHHHHHHHHHH
35.9221890473
23AcetylationRTRQQVFKNDARALE
HHHHHHHHHHHHHHH
55.8725953088
45PhosphorylationEEFKNNKSETSSKKI
HHHHCCCCCCCHHHH
48.5126074081
47PhosphorylationFKNNKSETSSKKIEE
HHCCCCCCCHHHHHH
45.4526074081
48PhosphorylationKNNKSETSSKKIEEL
HCCCCCCCHHHHHHH
35.7926074081
49PhosphorylationNNKSETSSKKIEELM
CCCCCCCHHHHHHHH
45.4426074081
60PhosphorylationEELMKIGSDVELLLR
HHHHHCCCCHHHHHH
41.7930108239
82UbiquitinationHTDHNTLKLVPRKDL
CCCCCCEEEEECHHH
45.4521890473
82UbiquitinationHTDHNTLKLVPRKDL
CCCCCCEEEEECHHH
45.4521890473
87UbiquitinationTLKLVPRKDLLVENV
CEEEEECHHHEECCC
46.8121890473
87UbiquitinationTLKLVPRKDLLVENV
CEEEEECHHHEECCC
46.8121890473
97GlutathionylationLVENVPYCDAPTQKQ
EECCCCCCCCCCCCC
2.7022555962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LYRM7_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LYRM7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LYRM7_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
UCRI_HUMANUQCRFS1physical
23168492
LYRM7_HUMANLYRM7physical
27499296
UCRI_HUMANUQCRFS1physical
27499296
ACPM_HUMANNDUFAB1physical
27499296

Drug and Disease Associations
Kegg Disease
OMIM Disease
615838Mitochondrial complex III deficiency, nuclear 8 (MC3DN8)
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LYRM7_HUMAN

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Related Literatures of Post-Translational Modification

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