dbPTM

FANCM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FANCM_HUMAN
UniProt AC	Q8IYD8
Protein Name	Fanconi anemia group M protein
Gene Name	FANCM
Organism	Homo sapiens (Human).
Sequence Length	2048
Subcellular Localization	Nucleus .
Protein Description	DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. [PubMed: 16116422 Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage]
Protein Sequence	MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVAAYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAIQKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGEFAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMFARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLNQDRLKSDI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSGRQRTLFQTWGS -CCCCCCHHHHHCCC	24.48	22468782
11	Phosphorylation	RQRTLFQTWGSSISR CCCHHHHHCCCCHHC	25.18	22468782
14	Phosphorylation	TLFQTWGSSISRSSG HHHHHCCCCHHCCCC	18.96	22468782
19	Phosphorylation	WGSSISRSSGTPGCS CCCCHHCCCCCCCCC	26.74	23186163
20	Phosphorylation	GSSISRSSGTPGCSS CCCHHCCCCCCCCCC	45.64	23186163
22	Phosphorylation	SISRSSGTPGCSSGT CHHCCCCCCCCCCCC	20.60	23186163
26	Phosphorylation	SSGTPGCSSGTERPQ CCCCCCCCCCCCCCC	37.40	23927012
27	Phosphorylation	SGTPGCSSGTERPQS CCCCCCCCCCCCCCC	54.53	23927012
29	Phosphorylation	TPGCSSGTERPQSPG CCCCCCCCCCCCCCC	30.67	23927012
34	Phosphorylation	SGTERPQSPGSSKAP CCCCCCCCCCCCCCC	33.63	23401153
37	Phosphorylation	ERPQSPGSSKAPLPA CCCCCCCCCCCCCCH	31.86	28450419
38	Phosphorylation	RPQSPGSSKAPLPAA CCCCCCCCCCCCCHH	38.46	28450419
52	Phosphorylation	AAEAQLESDDDVLLV HHHHHCCCCCCEEEH	55.73	24532841
123	Ubiquitination	GKTFIAAVVMYNFYR CHHHHHHHHHHHHHH	1.56	27667366
197	Ubiquitination	TPQVMVNDLSRGACP CCHHHHCCCCCCCCC	34.31	27667366
245	Phosphorylation	HFRILALSATPGSDI CCEEEEEECCCCCHH	25.21	23403867
247	Phosphorylation	RILALSATPGSDIKA EEEEEECCCCCHHHH	25.47	23403867
250	Phosphorylation	ALSATPGSDIKAVQQ EEECCCCCHHHHHHH	37.05	23403867
262	Ubiquitination	VQQVITNLLIGQIEL HHHHHHHHHHCCEEE	2.49	29967540
271	Phosphorylation	IGQIELRSEDSPDIL HCCEEECCCCCCCCC	59.38	24719451
274	Phosphorylation	IELRSEDSPDILTYS EEECCCCCCCCCCCC	22.03	24719451
281	Phosphorylation	SPDILTYSHERKVEK CCCCCCCCCCCCEEE	17.40	24719451
288	Ubiquitination	SHERKVEKLIVPLGE CCCCCEEEEEECCHH	46.64	29967540
310	Phosphorylation	TYIQILESFARSLIQ HHHHHHHHHHHHHHH	22.29	-
393	Phosphorylation	LCGIMDGTKGMTRSK HHHHHCCCCCCCCCC	21.84	-
397	Phosphorylation	MDGTKGMTRSKNELG HCCCCCCCCCCCCCC	40.22	-
400	Acetylation	TKGMTRSKNELGRNE CCCCCCCCCCCCCCH	51.67	7483995
413	Ubiquitination	NEDFMKLYNHLECMF CHHHHHHHHHHHHHH	8.60	29967540
416	Ubiquitination	FMKLYNHLECMFART HHHHHHHHHHHHHCC	4.89	29967540
432	Phosphorylation	STSANGISAIQQGDK CCCCCCCCCEECCCC	22.25	-
436	Ubiquitination	NGISAIQQGDKNKKF CCCCCEECCCCCCCE	56.81	29967540
439	Ubiquitination	SAIQQGDKNKKFVYS CCEECCCCCCCEEEC	76.98	29967540
442	Ubiquitination	QQGDKNKKFVYSHPK ECCCCCCCEEECCHH	49.83	29967540
462	Ubiquitination	EVVIEHFKSWNAENT HHHHHHHHHCCCCCC	57.37	29967540
470	Phosphorylation	SWNAENTTEKKRDET HCCCCCCCCCCCCCC	58.34	18452278
477	Phosphorylation	TEKKRDETRVMIFSS CCCCCCCCEEEEEHH	32.62	29083192
483	Phosphorylation	ETRVMIFSSFRDSVQ CCEEEEEHHHHHHHH	20.03	29083192
484	Phosphorylation	TRVMIFSSFRDSVQE CEEEEEHHHHHHHHH	17.35	29083192
492	Ubiquitination	FRDSVQEIAEMLSQH HHHHHHHHHHHHHCC	1.89	27667366
497	Ubiquitination	QEIAEMLSQHQPIIR HHHHHHHHCCCCCEE	25.06	29967540
518	Ubiquitination	HASGKSTKGFTQKEQ CCCCCCCCCCCHHHH	60.15	27667366
523	Ubiquitination	STKGFTQKEQLEVVK CCCCCCHHHHHHHHH	44.35	29967540
540	Ubiquitination	RDGGYNTLVSTCVGE HCCCCCCEEEEECCC	2.26	27667366
551	Ubiquitination	CVGEEGLDIGEVDLI ECCCCCCCCCCCEEE	58.67	27667366
609	Phosphorylation	QSNKRSIYKAISSNR CCCHHHHHHHHHCCC	8.80	22817900
614	Phosphorylation	SIYKAISSNRQVLHF HHHHHHHCCCCEEEE	29.89	22817900
643	Phosphorylation	KLHKMFITHGVYEPE HHHHHHHHCCCCCCC	11.00	28509920
647	Phosphorylation	MFITHGVYEPEKPSR HHHHCCCCCCCCCCC	30.29	28509920
650	Ubiquitination	THGVYEPEKPSRNLQ HCCCCCCCCCCCCCC	66.70	29967540
653	Phosphorylation	VYEPEKPSRNLQRKS CCCCCCCCCCCCCCH	44.89	28509920
660	Phosphorylation	SRNLQRKSSIFSYRD CCCCCCCHHHHCCCC	30.75	26434776
661	Phosphorylation	RNLQRKSSIFSYRDG CCCCCCHHHHCCCCC	30.59	26434776
664	Phosphorylation	QRKSSIFSYRDGMRQ CCCHHHHCCCCCCCC	20.00	23186163
665	Phosphorylation	RKSSIFSYRDGMRQS CCHHHHCCCCCCCCC	11.28	23186163
676	Ubiquitination	MRQSSLKKDWFLSEE CCCCCCCCCCCCCHH	66.54	29967540
807	Ubiquitination	ESNNLASDTFITHKK CCCCCCCCCEEECCH	39.78	27667366
816	Phosphorylation	FITHKKSSFIKNINQ EEECCHHHHHCCCCC	39.61	24719451
818	Ubiquitination	THKKSSFIKNINQGS ECCHHHHHCCCCCCC	3.45	27667366
823	Ubiquitination	SFIKNINQGSSSSVI HHHCCCCCCCCCCCC	49.72	-
825	Phosphorylation	IKNINQGSSSSVIES HCCCCCCCCCCCCCC	19.79	27251275
826	Phosphorylation	KNINQGSSSSVIESD CCCCCCCCCCCCCCH	33.19	27251275
827	Phosphorylation	NINQGSSSSVIESDE CCCCCCCCCCCCCHH	30.26	27251275
828	Phosphorylation	INQGSSSSVIESDEE CCCCCCCCCCCCHHH	29.12	27251275
832	Phosphorylation	SSSSVIESDEECAEI CCCCCCCCHHHHHHH	38.92	30576142
849	Ubiquitination	QTHIKPTKIVSLKKK HCCCCCCEEEECHHH	50.03	-
852	Phosphorylation	IKPTKIVSLKKKVSK CCCCEEEECHHHHCH	37.63	28258704
859	Acetylation	SLKKKVSKEIKKDQL ECHHHHCHHHHHHHH	67.46	18584559
862	Acetylation	KKVSKEIKKDQLKKE HHHCHHHHHHHHHHH	51.92	18584565
867	Acetylation	EIKKDQLKKENNHGI HHHHHHHHHHCCCCC	53.02	18584571
872	Ubiquitination	QLKKENNHGIIDSVD HHHHHCCCCCCCCCC	40.17	29967540
881	Ubiquitination	IIDSVDNDRNSTVEN CCCCCCCCCCCHHHH	46.83	27667366
892	Ubiquitination	TVENIFQEDLPNDKR HHHHHHHHCCCCCCC	51.25	27667366
898	Ubiquitination	QEDLPNDKRTSDTDE HHCCCCCCCCCCHHH	65.30	29967540
948	Phosphorylation	VLDSGYNSFNDEKSV CHHCCCCCCCCCCCC	19.55	25159151
995	Phosphorylation	ANVERFLSYSPPPLS HCHHHHHCCCCCCCC	22.35	28387310
996	Phosphorylation	NVERFLSYSPPPLSG CHHHHHCCCCCCCCC	27.61	28450419
997	Phosphorylation	VERFLSYSPPPLSGL HHHHHCCCCCCCCCC	27.79	28348404
1002	Phosphorylation	SYSPPPLSGLSDLEY CCCCCCCCCCCHHHH	43.38	26074081
1005	Phosphorylation	PPPLSGLSDLEYEIA CCCCCCCCHHHHHHH	43.61	23186163
1045	Phosphorylation	LSHSAVNSQQNLELN ECCHHCCCCCCEECC	26.92	-
1067	Phosphorylation	PSEKSCLYDIPNDNI CCCCCCCEECCCCCC	19.02	27642862
1158	Phosphorylation	PLNSKSESLPVSDKT CCCCCCCCCCCCCCC	45.09	25159151
1162	Phosphorylation	KSESLPVSDKTAISE CCCCCCCCCCCCCCC	31.30	25159151
1176	Ubiquitination	ETPLVSQFLISDELL CCCCCHHHHHCCHHH	5.22	27667366
1187	Ubiquitination	DELLLDNNSELQDQI CHHHCCCCHHHHHHH	36.21	27667366
1202	Ubiquitination	TRDANSFKSRDQRGV HHCHHHHHCHHHHCC	44.39	27667366
1213	Ubiquitination	QRGVQEEKVKNHEDI HHCCCHHHHCCCHHH	58.73	27667366
1322	Phosphorylation	AKNEELLSPGYSQFS HCCHHHCCCCCCCCC	28.98	21815630
1326	Phosphorylation	ELLSPGYSQFSLPVQ HHCCCCCCCCCCCCC	30.57	25627689
1342	O-linked_Glycosylation	KVMSTPLSKSNTLNS HHHCCCCCCCCCHHH	34.93	30379171
1349	Phosphorylation	SKSNTLNSFSKIRKE CCCCCHHHHHHHHHH	33.73	24719451
1352	Acetylation	NTLNSFSKIRKEILK CCHHHHHHHHHHHHC	44.51	25953088
1413	Phosphorylation	VEDGQLLTSNESEDD CCCCCCCCCCCCCCH	37.79	30576142
1414	Phosphorylation	EDGQLLTSNESEDDE CCCCCCCCCCCCCHH	38.27	29449344
1417	Phosphorylation	QLLTSNESEDDEIFR CCCCCCCCCCHHHHH	51.04	25849741
1437	Phosphorylation	AKGNVLNSPEDQKNS HHCCCCCCHHHHCCC	26.04	29255136
1444	Phosphorylation	SPEDQKNSEVDSPLH CHHHHCCCCCCCHHH	46.13	21815630
1448	Phosphorylation	QKNSEVDSPLHAVKK HCCCCCCCHHHHHHH	34.24	21815630
1551	Ubiquitination	DFLNDETQLSQAIND HHHCCHHHHHHHCCH	36.75	30230243
1568	Phosphorylation	MRAIYMKSLRSPMMN HHHHHHHHCCCHHHC	16.69	28122231
1571	Phosphorylation	IYMKSLRSPMMNNKY HHHHHCCCHHHCCCH	23.57	25159151
1577	Ubiquitination	RSPMMNNKYKMIHKT CCHHHCCCHHHHHHH	41.04	30230243
1673	Phosphorylation	RIILPDDSSEEENNV CEECCCCCCCCCCCC	47.21	25159151
1674	Phosphorylation	IILPDDSSEEENNVN EECCCCCCCCCCCCC	56.90	10997877
1686	Phosphorylation	NVNDKRESNIAVNPS CCCCCHHHCCCCCHH	37.25	-
1693	Phosphorylation	SNIAVNPSTVKKNKQ HCCCCCHHHHCCCCC	40.40	-
1720	Phosphorylation	SAQSKVRSTPRVNPL CHHHHHCCCCCCCHH	45.83	20363803
1721	Phosphorylation	AQSKVRSTPRVNPLA HHHHHCCCCCCCHHH	12.44	20363803
1735	Phosphorylation	AKQSKQTSLNLKDTI HHHCCCCCCCHHHHH	16.86	-
1746	Phosphorylation	KDTISEVSDFKPQNH HHHHHHHHCCCCCCC	33.02	25627689
1758	Phosphorylation	QNHNEVQSTTPPFTT CCCCCCCCCCCCCCC	39.15	25627689
1759	Phosphorylation	NHNEVQSTTPPFTTV CCCCCCCCCCCCCCC	26.65	25627689
1760	Phosphorylation	HNEVQSTTPPFTTVD CCCCCCCCCCCCCCC	33.92	25159151
1771	Ubiquitination	TTVDSQKDCRKFPVP CCCCCCCCCCCCCCC	29.80	29967540
1780	Acetylation	RKFPVPQKDGSALED CCCCCCCCCCCCCCC	58.97	26051181
1783	Phosphorylation	PVPQKDGSALEDSST CCCCCCCCCCCCCCC	39.55	-
1794	Phosphorylation	DSSTSGASCSKSRPH CCCCCCCCCCCCCCC	23.58	25627689
1796	Phosphorylation	STSGASCSKSRPHLA CCCCCCCCCCCCCCC	31.04	25627689
1797	Ubiquitination	TSGASCSKSRPHLAG CCCCCCCCCCCCCCC	55.61	29967540
1829	O-linked_Glycosylation	VGGHEITSGLEVISS ECCEECCCCHHHHHH	47.22	30379171
1835	Phosphorylation	TSGLEVISSLRAIHG CCCHHHHHHHHHHHC	28.61	24719451
1836	Phosphorylation	SGLEVISSLRAIHGL CCHHHHHHHHHHHCC	15.68	25954137
1867	Phosphorylation	RMVVERRSQSEMLNS CCEEEEHHHHHHHHH	44.26	30576142
1869	Phosphorylation	VVERRSQSEMLNSVN EEEEHHHHHHHHHHC	26.64	30576142
1874	Phosphorylation	SQSEMLNSVNKNKFI HHHHHHHHHCHHHHH	24.09	30576142
1890	Ubiquitination	QIQHLQSMFERICVI HHHHHHHHHHHHEEE	2.33	-
1916	Ubiquitination	SRMFRRTKSYDSLLT HHHCHHCCCHHHHHH	45.25	-
2003	Phosphorylation	SVKRMANSSLQEISM HHHHHHCCCHHHHHH	23.92	30622161
2004	Phosphorylation	VKRMANSSLQEISMY HHHHHCCCHHHHHHH	33.60	30622161
2009	Phosphorylation	NSSLQEISMYAQVTH CCCHHHHHHHHHHHH	12.65	30622161
2011	Phosphorylation	SLQEISMYAQVTHQK CHHHHHHHHHHHHHH	6.26	30622161
2015	Phosphorylation	ISMYAQVTHQKAEEI HHHHHHHHHHHHHHH	13.40	30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1045	S	Phosphorylation	Kinase	ATR	Q13535	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	FBXW11	Q9UKB1	PMID:24658274
-	K	Ubiquitination	E3 ubiquitin ligase	BTRC	Q9Y297	PMID:19270156

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FANCM_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FANCM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FANCM_HUMAN	FANCM	physical	18285517
FANCA_HUMAN	FANCA	physical	18285517
FP100_HUMAN	C17orf70	physical	18285517
FANCE_HUMAN	FANCE	physical	18285517
FANCL_HUMAN	FANCL	physical	18285517
FAP24_HUMAN	C19orf40	physical	18285517
BLM_HUMAN	BLM	physical	20347428
FANCA_HUMAN	FANCA	physical	20347428
FP100_HUMAN	C17orf70	physical	20347428
RMI1_HUMAN	RMI1	physical	20347428
RFA1_HUMAN	RPA1	physical	20347428
FANCG_HUMAN	FANCG	physical	20347428
FANCE_HUMAN	FANCE	physical	20347428
FANCC_HUMAN	FANCC	physical	20347428
FANCF_HUMAN	FANCF	physical	20347428
RFA2_HUMAN	RPA2	physical	20347428
FAP24_HUMAN	C19orf40	physical	20347428
FANCB_HUMAN	FANCB	physical	20347428
FANCL_HUMAN	FANCL	physical	20347428
FANCA_HUMAN	FANCA	physical	20347429
FANCM_HUMAN	FANCM	physical	20347429
FANCG_HUMAN	FANCG	physical	20347429
FAP24_HUMAN	C19orf40	physical	20347429
CENPS_HUMAN	APITD1	physical	20347429
CENPX_HUMAN	STRA13	physical	20347429
FANCA_HUMAN	FANCA	physical	20064461
FANCE_HUMAN	FANCE	physical	20064461
FANCF_HUMAN	FANCF	physical	20064461
BLM_HUMAN	BLM	physical	20064461
RMI1_HUMAN	RMI1	physical	20064461
RMI2_HUMAN	RMI2	physical	20064461
TOP3A_HUMAN	TOP3A	physical	20064461
FAP24_HUMAN	C19orf40	physical	20064461
FAP24_HUMAN	C19orf40	physical	17289582
RMI1_HUMAN	RMI1	physical	17289582
FANCE_HUMAN	FANCE	physical	17289582
FANCC_HUMAN	FANCC	physical	17289582
FANCF_HUMAN	FANCF	physical	17289582
FANCA_HUMAN	FANCA	physical	17289582
FANCB_HUMAN	FANCB	physical	17289582
FANCG_HUMAN	FANCG	physical	17289582
FANCL_HUMAN	FANCL	physical	17289582
FANCA_HUMAN	FANCA	physical	16720839
FANCL_HUMAN	FANCL	physical	16720839
FP100_HUMAN	C17orf70	physical	16116422
FANCB_HUMAN	FANCB	physical	16116422
FANCG_HUMAN	FANCG	physical	16116422
FANCC_HUMAN	FANCC	physical	16116422
FANCE_HUMAN	FANCE	physical	16116422
FANCL_HUMAN	FANCL	physical	16116422
FANCF_HUMAN	FANCF	physical	16116422
FANCA_HUMAN	FANCA	physical	16116422
BLM_HUMAN	BLM	physical	16116422
TOP3A_HUMAN	TOP3A	physical	16116422
A4_HUMAN	APP	physical	21832049
FANCL_HUMAN	FANCL	physical	24910428
CENPS_HUMAN	APITD1	physical	20347428
CENPX_HUMAN	STRA13	physical	20347428
PCNA_HUMAN	PCNA	physical	28514442
MOC2B_HUMAN	MOCS2	physical	28514442
MOC2A_HUMAN	MOCS2	physical	28514442
PAF15_HUMAN	KIAA0101	physical	28514442
FAP24_HUMAN	C19orf40	physical	24003026
FANCI_HUMAN	FANCI	physical	26625197
FANCA_HUMAN	FANCA	physical	26625197
FP100_HUMAN	C17orf70	physical	26625197
FOXF1_HUMAN	FOXF1	physical	26625197
FAP20_HUMAN	C1orf86	physical	26625197
CENPS_HUMAN	APITD1	physical	26625197
CENPX_HUMAN	STRA13	physical	26625197
FAP24_HUMAN	C19orf40	physical	23932590
CENPS_HUMAN	APITD1	physical	24699063
CENPX_HUMAN	STRA13	physical	24699063
FANCC_HUMAN	FANCC	physical	24699063
FANCE_HUMAN	FANCE	physical	24699063
FANCF_HUMAN	FANCF	physical	24699063
FAP24_HUMAN	C19orf40	physical	24699063
BLM_HUMAN	BLM	physical	24699063
TOP3A_HUMAN	TOP3A	physical	24699063
PCNA_HUMAN	PCNA	physical	26825464
RMI1_HUMAN	RMI1	physical	22392978
RMI2_HUMAN	RMI2	physical	22392978
CENPS_HUMAN	APITD1	physical	22510687
CENPX_HUMAN	STRA13	physical	22510687
TELO2_HUMAN	TELO2	physical	20064461

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
614087	Fanconi anemia complementation group M (FANCM)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FANCM_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1437, AND MASSSPECTROMETRY.	19413330 [Abstract]