| UniProt ID | FOXF1_HUMAN | |
|---|---|---|
| UniProt AC | Q12946 | |
| Protein Name | Forkhead box protein F1 | |
| Gene Name | FOXF1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 379 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Probable transcription activator for a number of lung-specific genes.. | |
| Protein Sequence | MSSAPEKQQPPHGGGGGGGGGGGAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLSCPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPHHDSSVPASPLLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNPAANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAGGGSYYHQQVTYQDIKPCVM | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Acetylation | -MSSAPEKQQPPHGG -CCCCCCCCCCCCCC | 53.85 | 23236377 | |
| 39 | Phosphorylation | GPSKAKKTNAGIRRP CCCCCCCCCCCCCCC | 29.60 | - | |
| 52 | Phosphorylation | RPEKPPYSYIALIVM CCCCCCCCEEEHHHH | 18.81 | - | |
| 101 | Phosphorylation | NSVRHNLSLNECFIK HHHHHCEEHHHEEEE | 34.17 | 20873877 | |
| 108 | Sumoylation | SLNECFIKLPKGLGR EHHHEEEECCCCCCC | 38.18 | - | |
| 108 | Sumoylation | SLNECFIKLPKGLGR EHHHEEEECCCCCCC | 38.18 | - | |
| 108 | Ubiquitination | SLNECFIKLPKGLGR EHHHEEEECCCCCCC | 38.18 | 29967540 | |
| 136 | Phosphorylation | EFMFEEGSFRRRPRG HHCCCCCCCCCCCCH | 20.89 | 24719451 | |
| 291 | Phosphorylation | YIKQQPLSPCNPAAN HHHCCCCCCCCCCCC | 33.81 | - | |
| 331 | Phosphorylation | ELQGIPRYHSQSPSM HHCCCCCCCCCCCHH | 10.64 | 29396449 | |
| 333 | Phosphorylation | QGIPRYHSQSPSMCD CCCCCCCCCCCHHCC | 24.34 | 25159151 | |
| 335 | Phosphorylation | IPRYHSQSPSMCDRK CCCCCCCCCHHCCCC | 23.20 | 26657352 | |
| 337 | Phosphorylation | RYHSQSPSMCDRKEF CCCCCCCHHCCCCCE | 36.97 | 20873877 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FOXF1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FOXF1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FOXF1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SATB1_HUMAN | SATB1 | physical | 25609649 | |
| FUBP3_HUMAN | FUBP3 | physical | 25609649 | |
| HXD13_HUMAN | HOXD13 | physical | 25609649 | |
| SATB2_HUMAN | SATB2 | physical | 25609649 | |
| HXB13_HUMAN | HOXB13 | physical | 25609649 | |
| HXB9_HUMAN | HOXB9 | physical | 25609649 | |
| STRBP_HUMAN | STRBP | physical | 25609649 | |
| FOXF1_HUMAN | FOXF1 | physical | 25609649 | |
| GAPD1_HUMAN | GAPVD1 | physical | 25609649 | |
| FUBP2_HUMAN | KHSRP | physical | 25609649 | |
| CPSM_HUMAN | CPS1 | physical | 25609649 | |
| FLNC_HUMAN | FLNC | physical | 25609649 | |
| PUSL1_HUMAN | PUSL1 | physical | 25609649 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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