CCD51_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD51_HUMAN
• UniProt AC: Q96ER9
• Protein Name: Coiled-coil domain-containing protein 51
• Gene Name: CCDC51
• Organism: Homo sapiens (Human).
• Sequence Length: 411
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
129	Acetylation	DLEVHQAKLKEVRDR HHHHHHHHHHHHHHH	54.22	25953088
129	Succinylation	DLEVHQAKLKEVRDR HHHHHHHHHHHHHHH	54.22	27452117
162	Succinylation	HRMLQEEKRLRTAYL HHHHHHHHHHHHHHH	56.85	27452117
200 (in isoform 2)	Ubiquitination	-	21.89	21906983
231 (in isoform 1)	Ubiquitination	-	35.91	21906983
273 (in isoform 2)	Ubiquitination	-	3.00	21906983
304 (in isoform 1)	Ubiquitination	-	38.39	21906983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD51_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD51_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD51_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLAK_HUMAN	JUP	physical	26186194
NFH_HUMAN	NEFH	physical	26186194
TGM1_HUMAN	TGM1	physical	26186194
ARGI1_HUMAN	ARG1	physical	26186194
TGM3_HUMAN	TGM3	physical	26186194
POF1B_HUMAN	POF1B	physical	26186194
FABP5_HUMAN	FABP5	physical	26186194
SAP3_HUMAN	GM2A	physical	26186194
CBPA4_HUMAN	CPA4	physical	26186194
PKP1_HUMAN	PKP1	physical	26186194
CDSN_HUMAN	CDSN	physical	26186194
LX12B_HUMAN	ALOX12B	physical	26186194
PLBL1_HUMAN	PLBD1	physical	26186194
PAI2_HUMAN	SERPINB2	physical	26186194
TGM5_HUMAN	TGM5	physical	26186194
FBX50_HUMAN	NCCRP1	physical	26186194
DUS14_HUMAN	DUSP14	physical	26186194
PKP3_HUMAN	PKP3	physical	26186194
ECM1_HUMAN	ECM1	physical	26186194
OTU1_HUMAN	YOD1	physical	26186194
KPRP_HUMAN	KPRP	physical	26186194
OTU1_HUMAN	YOD1	physical	28514442
PLBL1_HUMAN	PLBD1	physical	28514442
PAI2_HUMAN	SERPINB2	physical	28514442
PLAK_HUMAN	JUP	physical	28514442
TGM5_HUMAN	TGM5	physical	28514442
LX12B_HUMAN	ALOX12B	physical	28514442
ARGI1_HUMAN	ARG1	physical	28514442
CDSN_HUMAN	CDSN	physical	28514442
FBX50_HUMAN	NCCRP1	physical	28514442
PKP3_HUMAN	PKP3	physical	28514442
PKP1_HUMAN	PKP1	physical	28514442
ECM1_HUMAN	ECM1	physical	28514442
TGM1_HUMAN	TGM1	physical	28514442
POF1B_HUMAN	POF1B	physical	28514442
DSG1_HUMAN	DSG1	physical	28514442
DUS14_HUMAN	DUSP14	physical	28514442
SAP3_HUMAN	GM2A	physical	28514442
KPRP_HUMAN	KPRP	physical	28514442
CBPA4_HUMAN	CPA4	physical	28514442
NFH_HUMAN	NEFH	physical	28514442
TPM2_HUMAN	TPM2	physical	28514442
DESP_HUMAN	DSP	physical	28514442
TGM3_HUMAN	TGM3	physical	28514442
NEUR2_HUMAN	NEU2	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.