| UniProt ID | UBX10_HUMAN | |
|---|---|---|
| UniProt AC | Q96LJ8 | |
| Protein Name | UBX domain-containing protein 10 {ECO:0000305} | |
| Gene Name | UBXN10 {ECO:0000312|HGNC:HGNC:26354} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 280 | |
| Subcellular Localization | Cell projection, cilium . Recruited to cilia in a VCP-dependent manner. | |
| Protein Description | VCP/p97-binding protein required for ciliogenesis. [PubMed: 26389662 Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia] | |
| Protein Sequence | MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAHHIPSPPPAIPYELPSSQKPGACAPKSPNQGASDEIPELQQQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSLQLSSIRALYQDETGTMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQRFVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 65 | Phosphorylation | VCAHHIPSPPPAIPY EEEECCCCCCCCCCC | 49.81 | 27251275 | |
| 72 | Phosphorylation | SPPPAIPYELPSSQK CCCCCCCCCCCCCCC | 24.80 | 22817900 | |
| 87 | Phosphorylation | PGACAPKSPNQGASD CCCCCCCCCCCCCCC | 28.20 | 23917254 | |
| 132 | Phosphorylation | LEEEAVETVAKKASS CHHHHHHHHHHHHHH | 21.11 | - | |
| 138 | Phosphorylation | ETVAKKASSLQLSSI HHHHHHHHHCCHHHH | 40.22 | 28270605 | |
| 139 | Phosphorylation | TVAKKASSLQLSSIR HHHHHHHHCCHHHHH | 25.62 | 28270605 | |
| 143 | Phosphorylation | KASSLQLSSIRALYQ HHHHCCHHHHHHHEE | 15.68 | 28270605 | |
| 144 | Phosphorylation | ASSLQLSSIRALYQD HHHCCHHHHHHHEEC | 25.37 | 25954137 | |
| 149 | Phosphorylation | LSSIRALYQDETGTM HHHHHHHEECCCCCC | 16.97 | 28270605 | |
| 153 | Phosphorylation | RALYQDETGTMKTSE HHHEECCCCCCCCCH | 46.36 | 28270605 | |
| 155 | Phosphorylation | LYQDETGTMKTSEED HEECCCCCCCCCHHH | 23.94 | 28270605 | |
| 205 | Phosphorylation | RLLLAVRSPTGQRFV EEEEEEECCCCCCHH | 21.88 | 23917254 | |
| 207 | Phosphorylation | LLAVRSPTGQRFVRH EEEEECCCCCCHHHH | 47.39 | 23312004 | |
| 240 | Phosphorylation | KTSYRHCSIETMEVP CCCCCCCCEEEECCC | 19.82 | 24719451 | |
| 243 | Phosphorylation | YRHCSIETMEVPRRR CCCCCEEEECCCHHH | 19.57 | 24719451 | |
| 266 | Acetylation | QECRIPHKSVLGISL HHCCCCCCCEECEEC | 36.58 | 19413330 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UBX10_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBX10_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBX10_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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