UBLH2_SCHPO - dbPTM
UBLH2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBLH2_SCHPO
UniProt AC Q9UUB6
Protein Name Ubiquitin carboxyl-terminal hydrolase 2
Gene Name uch2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 300
Subcellular Localization Nucleus .
Protein Description Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin..
Protein Sequence MSWTTIESDAGVFTDLIENLGVKDVEVDELYSLDVDSLRQFPDIYGIIFLFKWNSKVDKPDGTMDYDSMDNIFFAKQVINNACATQALLSVLLNHSDEIDLGTTLSEFKDFSKTLPPELKGEALGNSEHIRCCHNSFARSDPFISEEVRAATDEDEVYHFIAYTNINNVFYELDGLQAAPINHGSCTKEEFAEKAVSVIQARIANYDPAEIRFNLMVICKDKKASLLTREDLTDEEKAASIAVEDEKRLRWKRENQLRRHNFVGLFVELSKLLVKDRIDKNTWNSTLETAKAKYASQKRP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
140PhosphorylationCHNSFARSDPFISEE
CCCHHHCCCCCCCHH
46.3225720772
233PhosphorylationLLTREDLTDEEKAAS
CCCHHHCCCHHHHHH
54.4028889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBLH2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBLH2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBLH2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATF1_SCHPOatf1genetic
15533439
RPN12_SCHPOrpn12genetic
15533439
RPN1_SCHPOmts4genetic
15533439
RPN11_SCHPOrpn11genetic
15533439
PRS4_SCHPOrpt2genetic
15533439
RPN1_SCHPOmts4physical
10872838
RPN10_SCHPOrpn10physical
15533439
RPN2_SCHPOrpn2physical
20838651
RPN1_SCHPOmts4physical
20838651
PRS7_SCHPOrpt1physical
20838651
PRS10_SCHPOrpt4physical
20838651
PRS6A_SCHPOrpt5physical
20838651
PRS4_SCHPOrpt2physical
20838651
PRS8_SCHPOrpt6physical
20838651
PRS6B_SCHPOrpt3physical
20838651
YOY4_SCHPOrpn1301physical
20838651
RPN3_SCHPOrpn3physical
20838651
RPN6_SCHPOrpn6physical
20838651
RPN7_SCHPOrpn7physical
20838651
PSA1_SCHPOscl1physical
20838651
PSA2_SCHPOpre8physical
20838651
PSA6_SCHPOpre5physical
20838651
PSB1_SCHPOpre3physical
20838651
RPN8_SCHPOrpn8physical
20838651
PSA5_SCHPOpup2physical
20838651
RPN9_SCHPOrpn9physical
20838651
PSB5_SCHPOpts1physical
20838651
ECM29_SCHPOecm29physical
20838651
RPN12_SCHPOrpn12physical
20838651
RPN11_SCHPOrpn11physical
20838651
PSB7_SCHPOpre4physical
20838651
PSB6_SCHPOpam1physical
20838651
PSA4_SCHPOpre6physical
20838651
PSB2_SCHPOpup1physical
20838651
PSB4_SCHPOpre1physical
20838651
RPN10_SCHPOrpn10physical
20838651
PSB3_SCHPOpup3physical
20838651
YD58_SCHPOnas6physical
20838651
PSA3_SCHPOpre9physical
20838651
PSA7_SCHPOpre10physical
20838651
DDB1_SCHPOddb1genetic
22681890
ARB1_SCHPOarb1genetic
22681890
RYH1_SCHPOryh1genetic
22681890
SYJ2_SCHPOsyj2genetic
22681890
CLR4_SCHPOclr4genetic
22681890
RAD5_SCHPOrad8genetic
22681890
YLO2_SCHPOtma23genetic
22681890
DAD1_SCHPOdad1genetic
22681890
RICTR_SCHPOste20genetic
22681890
PAB2_SCHPOpab2genetic
22681890
HUS1_SCHPOhus1genetic
22681890
YE8A_SCHPOSPAC9G1.10cgenetic
22681890
PDT1_SCHPOpdt1genetic
22681890
TOM70_SCHPOtom70genetic
22681890
YAY1_SCHPOSPAC4H3.01genetic
22681890
TBA2_SCHPOatb2genetic
22681890
UBP2_SCHPOubp2genetic
22681890
UBL1_SCHPOned8physical
23496905
UBLH1_SCHPOuch1genetic
23496905
NESP1_SCHPOnep1genetic
23496905
NEP2_SCHPOnep2genetic
23496905
CSN5_SCHPOcsn5genetic
23496905
UBLH2_SCHPOuch2physical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBLH2_SCHPO

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Related Literatures of Post-Translational Modification

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