RPN10_SCHPO - dbPTM
RPN10_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RPN10_SCHPO
UniProt AC O94444
Protein Name 26S proteasome regulatory subunit rpn10
Gene Name rpn10
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 243
Subcellular Localization Nucleus .
Protein Description Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation..
Protein Sequence MVLEATMILIDNSEWMINGDYIPTRFEAQKDTVHMIFNQKINDNPENMCGLMTIGDNSPQVLSTLTRDYGKFLSAMHDLPVRGNAKFGDGIQIAQLALKHRENKIQRQRIVAFVGSPIVEDEKNLIRLAKRMKKNNVAIDIIHIGELQNESALQHFIDAANSSDSCHLVSIPPSPQLLSDLVNQSPIGQGVVASQNQFEYGVDPNLDVELALALELSMAEERARQEVAAQKSSEETEDKKMQE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
232PhosphorylationQEVAAQKSSEETEDK
HHHHHHHCCHHHHHH		30.7925720772
233PhosphorylationEVAAQKSSEETEDKK
HHHHHHCCHHHHHHH		46.6229996109
236PhosphorylationAQKSSEETEDKKMQE
HHHCCHHHHHHHHCC		45.4929996109
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RPN10_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RPN10_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RPN10_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATF1_SCHPOatf1genetic
10809753
RPN11_SCHPOrpn11genetic
10809753
RPN1_SCHPOmts4genetic
10809753
RHP23_SCHPOrhp23genetic
11584278
RPN1_SCHPOmts4physical
12615927
RPN2_SCHPOrpn2physical
12615927
APC1_SCHPOcut4physical
12615927
CUT9_SCHPOcut9physical
12615927
RPN12_SCHPOrpn12physical
10809753
RPN1_SCHPOmts4physical
12783882
RPN11_SCHPOrpn11physical
12783882
RPN12_SCHPOrpn12physical
12783882
PRS4_SCHPOrpt2physical
12783882
ATF1_SCHPOatf1physical
11584278
RPN1_SCHPOmts4physical
11584278
UBLH2_SCHPOuch2physical
15533439
UBP6_SCHPOubp6physical
15533439
RPN12_SCHPOrpn12physical
20739285
PSD12_HUMANPSMD12physical
12783882
PRS6A_SCHPOrpt5physical
22307589
RHP23_SCHPOrhp23genetic
25306921
RPN10_SCHPOrpn10physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RPN10_SCHPO

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Related Literatures of Post-Translational Modification

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