| UniProt ID | PCDBG_HUMAN | |
|---|---|---|
| UniProt AC | Q9NRJ7 | |
| Protein Name | Protocadherin beta-16 | |
| Gene Name | PCDHB16 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 776 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.. | |
| Protein Sequence | MEIGWMHNRRQRQVLVFFVLLSLSGAGAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLINEKLDREELCGPTEPCILHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPENSPLGTEFPLNHALDLDVGSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDREEEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVATVSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRIKATDGGGLSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENSPEIVVAVFSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEFRVSATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHVLLVDGFSQPFLPLPEAAPGQTQANSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSMPEGPFPGRLVDVSGTGTLSQSYQYEVCLTGGSETSEFKFLKPIIPNFSP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 57 | Phosphorylation | KDLGLGLTEMSTRKA CCCCCCCHHHCHHHE | 28.04 | 23403867 | |
| 60 | Phosphorylation | GLGLTEMSTRKARII CCCCHHHCHHHEEEH | 20.87 | 23403867 | |
| 61 | Phosphorylation | LGLTEMSTRKARIIS CCCHHHCHHHEEEHH | 34.57 | 23403867 | |
| 191 | Phosphorylation | EFRDGRKYPELVLDK ECCCCCCCCCCEECC | 10.69 | 22817900 | |
| 298 | Phosphorylation | TLEVNPMTGEVRLRK CEEECCCCCEEEEEE | 31.29 | - | |
| 313 | Phosphorylation | QVDFEMVTSYEVRIK ECCEEEECEEEEEEE | 25.04 | 28509920 | |
| 314 | Phosphorylation | VDFEMVTSYEVRIKA CCEEEECEEEEEEEE | 14.11 | 28509920 | |
| 315 | Phosphorylation | DFEMVTSYEVRIKAT CEEEECEEEEEEEEC | 14.74 | 28509920 | |
| 401 | Phosphorylation | KPSVKNFYTLVTERA CHHHHHHHHHHHHHH | 14.46 | 22617229 | |
| 402 | O-linked_Glycosylation | PSVKNFYTLVTERAL HHHHHHHHHHHHHHC | 15.60 | 30620550 | |
| 402 | Phosphorylation | PSVKNFYTLVTERAL HHHHHHHHHHHHHHC | 15.60 | 22617229 | |
| 417 | Phosphorylation | DREARAEYNITLTVT CHHHHHHEEEEEEEE | 15.75 | 22210691 | |
| 418 | N-linked_Glycosylation | REARAEYNITLTVTD HHHHHHEEEEEEEEE | 16.57 | UniProtKB CARBOHYD | |
| 424 | Phosphorylation | YNITLTVTDMGTPRL EEEEEEEEECCCCCC | 18.29 | 22210691 | |
| 436 | N-linked_Glycosylation | PRLKTEHNITVQISD CCCEEECEEEEEEEE | 25.95 | UniProtKB CARBOHYD | |
| 567 | N-linked_Glycosylation | FVLYPLQNGSAPCTE EEEEECCCCCCCCCC | 54.81 | UniProtKB CARBOHYD | |
| 768 | Ubiquitination | TSEFKFLKPIIPNFS CCCEEECCCCCCCCC | 36.98 | 32142685 | |
| 775 | Phosphorylation | KPIIPNFSP------ CCCCCCCCC------ | 36.02 | 22199227 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCDBG_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCDBG_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCDBG_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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