| UniProt ID | PCDBA_HUMAN | |
|---|---|---|
| UniProt AC | Q9UN67 | |
| Protein Name | Protocadherin beta-10 | |
| Gene Name | PCDHB10 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 800 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.. | |
| Protein Sequence | MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHAPVFQDKETVLKISENTAEGTAFRLERAQDPDGGLNGIQNYTISPNSFFHINISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELVNSYKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHLLLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGPGTSEFKFLKPVISDIQAQGPGRKGEENSTFRNSFGFNIQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 143 | Phosphorylation | KETVLKISENTAEGT CCEEEEEECCCCCCC | 24.17 | - | |
| 146 | Phosphorylation | VLKISENTAEGTAFR EEEEECCCCCCCEEE | 23.26 | - | |
| 169 | N-linked_Glycosylation | GGLNGIQNYTISPNS CCCCCCEEEEECCCC | 33.71 | UniProtKB CARBOHYD | |
| 181 | N-linked_Glycosylation | PNSFFHINISGGDEG CCCEEEEEECCCCCC | 17.50 | UniProtKB CARBOHYD | |
| 209 | Phosphorylation | REEQGELSLTLTALD HHHCCCEEEEEEEEC | 18.27 | 27732954 | |
| 211 | Phosphorylation | EQGELSLTLTALDGG HCCCEEEEEEEECCC | 20.77 | 27732954 | |
| 213 | Phosphorylation | GELSLTLTALDGGSP CCEEEEEEEECCCCC | 21.68 | 27732954 | |
| 418 | N-linked_Glycosylation | REIRAEYNITITVTD HHHHHHCCEEEEEEC | 19.21 | UniProtKB CARBOHYD | |
| 420 | Phosphorylation | IRAEYNITITVTDLG HHHHCCEEEEEECCC | 13.63 | 22817900 | |
| 428 | Phosphorylation | ITVTDLGTPRLKTEH EEEECCCCCCCCCCC | 16.72 | 22817900 | |
| 436 | N-linked_Glycosylation | PRLKTEHNITVLVSD CCCCCCCCEEEEEEC | 25.95 | UniProtKB CARBOHYD | |
| 567 | N-linked_Glycosylation | FVLYPLQNGSAPCTE EEEEECCCCCCCCCC | 54.81 | UniProtKB CARBOHYD | |
| 767 | Ubiquitination | GPGTSEFKFLKPVIS CCCCCCEEECHHHHH | 45.82 | 23000965 | |
| 770 | Ubiquitination | TSEFKFLKPVISDIQ CCCEEECHHHHHHHH | 40.13 | 23000965 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCDBA_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCDBA_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCDBA_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PCDBA_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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