| UniProt ID | KI3S1_HUMAN | |
|---|---|---|
| UniProt AC | Q14943 | |
| Protein Name | Killer cell immunoglobulin-like receptor 3DS1 | |
| Gene Name | KIR3DS1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 382 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.. | |
| Protein Sequence | MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHREWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKKKCCCNGPRACREQK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 92 | N-linked_Glycosylation | VTTAHAGNYTCRGSH CCEEECCCEEECCCC | 29.71 | UniProtKB CARBOHYD | |
| 179 | N-linked_Glycosylation | HDGVSKANFSIGSMM CCCCHHCCCCHHHHH | 34.63 | UniProtKB CARBOHYD | |
| 218 | Phosphorylation | DPLDIVVTGLYEKPS CCCEEEEEECCCCCC | 15.58 | 24719451 | |
| 221 | Phosphorylation | DIVVTGLYEKPSLSA EEEEEECCCCCCCCC | 24.21 | 24719451 | |
| 225 | Phosphorylation | TGLYEKPSLSAQPGP EECCCCCCCCCCCCC | 46.13 | 28302921 | |
| 227 | Phosphorylation | LYEKPSLSAQPGPKV CCCCCCCCCCCCCCC | 29.24 | 28302921 | |
| 245 | Phosphorylation | ESVTLSCSSRSSYDM CCEEEEECCCCCEEC | 25.96 | - | |
| 246 | Phosphorylation | SVTLSCSSRSSYDMY CEEEEECCCCCEECC | 40.27 | - | |
| 273 | N-linked_Glycosylation | LPAVRKVNRTFQADF CHHHHCCCCEEECCC | 40.07 | UniProtKB CARBOHYD | |
| 296 | Phosphorylation | GTYRCFGSFRHSPYE CCEEEEEECCCCCCC | 10.00 | 11733001 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KI3S1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KI3S1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KI3S1_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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