KI3S1_HUMAN - dbPTM
KI3S1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KI3S1_HUMAN
UniProt AC Q14943
Protein Name Killer cell immunoglobulin-like receptor 3DS1
Gene Name KIR3DS1
Organism Homo sapiens (Human).
Sequence Length 382
Subcellular Localization Cell membrane
Single-pass type I membrane protein.
Protein Description Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells..
Protein Sequence MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHREWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKKKCCCNGPRACREQK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
92N-linked_GlycosylationVTTAHAGNYTCRGSH
CCEEECCCEEECCCC
29.71UniProtKB CARBOHYD
179N-linked_GlycosylationHDGVSKANFSIGSMM
CCCCHHCCCCHHHHH
34.63UniProtKB CARBOHYD
218PhosphorylationDPLDIVVTGLYEKPS
CCCEEEEEECCCCCC
15.5824719451
221PhosphorylationDIVVTGLYEKPSLSA
EEEEEECCCCCCCCC
24.2124719451
225PhosphorylationTGLYEKPSLSAQPGP
EECCCCCCCCCCCCC
46.1328302921
227PhosphorylationLYEKPSLSAQPGPKV
CCCCCCCCCCCCCCC
29.2428302921
245PhosphorylationESVTLSCSSRSSYDM
CCEEEEECCCCCEEC
25.96-
246PhosphorylationSVTLSCSSRSSYDMY
CEEEEECCCCCEECC
40.27-
273N-linked_GlycosylationLPAVRKVNRTFQADF
CHHHHCCCCEEECCC
40.07UniProtKB CARBOHYD
296PhosphorylationGTYRCFGSFRHSPYE
CCEEEEEECCCCCCC
10.0011733001

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KI3S1_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KI3S1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KI3S1_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KLK7_HUMANKLK7physical
26186194
CALL5_HUMANCALML5physical
26186194
SPB4_HUMANSERPINB4physical
26186194
SPB3_HUMANSERPINB3physical
26186194
SPB5_HUMANSERPINB5physical
26186194
TGM3_HUMANTGM3physical
26186194
RNAS7_HUMANRNASE7physical
26186194
CALL3_HUMANCALML3physical
26186194
POF1B_HUMANPOF1Bphysical
26186194
SPB7_HUMANSERPINB7physical
26186194
NGAL_HUMANLCN2physical
26186194
FILA_HUMANFLGphysical
26186194
SAP3_HUMANGM2Aphysical
26186194
KI2L2_HUMANKIR2DL2physical
26186194
LX12B_HUMANALOX12Bphysical
26186194
PEPL_HUMANPPLphysical
26186194
S10A7_HUMANS100A7physical
26186194
INVO_HUMANIVLphysical
26186194
SPA12_HUMANSERPINA12physical
26186194
IL36G_HUMANIL36Gphysical
26186194
PAI2_HUMANSERPINB2physical
26186194
CATL2_HUMANCTSVphysical
26186194
KI2L2_HUMANKIR2DL2physical
28514442
SPB7_HUMANSERPINB7physical
28514442
NGAL_HUMANLCN2physical
28514442
SPB4_HUMANSERPINB4physical
28514442
POF1B_HUMANPOF1Bphysical
28514442
INVO_HUMANIVLphysical
28514442
KLK7_HUMANKLK7physical
28514442
SPB5_HUMANSERPINB5physical
28514442
CALL5_HUMANCALML5physical
28514442
CALL3_HUMANCALML3physical
28514442
SPB3_HUMANSERPINB3physical
28514442
RNAS7_HUMANRNASE7physical
28514442
SAP3_HUMANGM2Aphysical
28514442
IL36G_HUMANIL36Gphysical
28514442
SPA12_HUMANSERPINA12physical
28514442
PEPL_HUMANPPLphysical
28514442
LX12B_HUMANALOX12Bphysical
28514442
CATL2_HUMANCTSVphysical
28514442
FILA_HUMANFLGphysical
28514442
PAI2_HUMANSERPINB2physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KI3S1_HUMAN

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Related Literatures of Post-Translational Modification

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