FILA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FILA_HUMAN
• UniProt AC: P20930
• Protein Name: Filaggrin
• Gene Name: FLG
• Organism: Homo sapiens (Human).
• Sequence Length: 4061
• Subcellular Localization: Cytoplasmic granule . In the stratum granulosum of the epidermis, localized within keratohyalin granules (PubMed:1429717). In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (PubMed:21531719).
• Protein Description: Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis..
• Protein Sequence: MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAFGKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	IINLFKQYSKKDKNT HHHHHHHHCCCCCCC	24.05	29083192
19	Phosphorylation	INLFKQYSKKDKNTD HHHHHHHCCCCCCCC	30.64	29083192
29	Phosphorylation	DKNTDTLSKKELKEL CCCCCCCCHHHHHHH	43.72	23612710
85	Phosphorylation	VFKLAQAYYESTRKE HHHHHHHHHHHHCCC	8.83	-
86	Phosphorylation	FKLAQAYYESTRKEN HHHHHHHHHHHCCCC	13.35	-
126	Phosphorylation	KENRKRPSSLERRNN HHHHCCCHHHHHHHC	52.14	20068231
127	Phosphorylation	ENRKRPSSLERRNNR HHHCCCHHHHHHHCC	36.61	20068231
143	Phosphorylation	GNKGRSKSPRETGGK CCCCCCCCCCCCCCC	30.36	27251275
147	Phosphorylation	RSKSPRETGGKRHES CCCCCCCCCCCCCCC	53.14	27251275
154	Phosphorylation	TGGKRHESSSEKKER CCCCCCCCCHHHHHC	32.79	27251275
155	Phosphorylation	GGKRHESSSEKKERK CCCCCCCCHHHHHCC	39.26	27251275
156	Phosphorylation	GKRHESSSEKKERKG CCCCCCCHHHHHCCC	63.82	27251275
164	Phosphorylation	EKKERKGYSPTHREE HHHHCCCCCCCHHHH	17.95	18691976
165	Phosphorylation	KKERKGYSPTHREEE HHHCCCCCCCHHHHH	31.80	20068231
167	Phosphorylation	ERKGYSPTHREEEYG HCCCCCCCHHHHHHH	27.85	20068231
173	Phosphorylation	PTHREEEYGKNHHNS CCHHHHHHHCCCCCC	36.36	20068231
215	Phosphorylation	EDNEEGVYDYENTGR CCCCCCCCCCCCCCC	24.54	-
217	Phosphorylation	NEEGVYDYENTGRMT CCCCCCCCCCCCCCC	8.06	-
236	Phosphorylation	QSGHIATYYTIQDEA HHCCEEEEEEECCCH	6.92	22817900
295	Phosphorylation	RTRKRRGSRVSQDRD HCCHHCCCCCCCCCC	27.91	17494752
303	Phosphorylation	RVSQDRDSEGHSEDS CCCCCCCCCCCCCCC	46.50	-
307	Phosphorylation	DRDSEGHSEDSERHS CCCCCCCCCCCHHCC	54.69	-
314	Phosphorylation	SEDSERHSGSASRNH CCCCHHCCCCCCCCC	40.44	-
316	Phosphorylation	DSERHSGSASRNHHG CCHHCCCCCCCCCCC	26.53	-
318	Phosphorylation	ERHSGSASRNHHGSA HHCCCCCCCCCCCCC	35.00	-
343	Methylation	PRSHDEDRASHGHSA CCCCCCCHHHCCCCC	35.62	-
345	Phosphorylation	SHDEDRASHGHSADS CCCCCHHHCCCCCCC	30.78	-
352	Phosphorylation	SHGHSADSSRQSGTR HCCCCCCCCCCCCCC	27.43	-
353	Phosphorylation	HGHSADSSRQSGTRH CCCCCCCCCCCCCCC	34.58	-
369	Phosphorylation	ETSSRGQTASSHEQA CCCCCCCCCCHHHHH	31.19	22210691
371	Phosphorylation	SSRGQTASSHEQARS CCCCCCCCHHHHHHC	35.30	22210691
372	Phosphorylation	SRGQTASSHEQARSS CCCCCCCHHHHHHCC	28.69	30576142
378	Phosphorylation	SSHEQARSSPGERHG CHHHHHHCCCCCCCC	43.85	26699800
379	Phosphorylation	SHEQARSSPGERHGS HHHHHHCCCCCCCCC	31.22	22210691
394	Phosphorylation	GHQQSADSSRHSATG CCCCCCCCCCCCCCC	29.05	30576142
398	Phosphorylation	SADSSRHSATGRGQA CCCCCCCCCCCCCCH	26.81	30576142
410	Phosphorylation	GQASSAVSDRGHRGS CCHHHCCCCCCCCCC	22.70	24706070
432	Phosphorylation	SEGHSENSDTQSVSG CCCCCCCCCCCCCCC	37.67	-
434	Phosphorylation	GHSENSDTQSVSGHG CCCCCCCCCCCCCCC	23.67	-
462	Phosphorylation	RGRSGERSGRSGSSL CCCCCCCCCCCCCCC	33.97	29978859
465	Phosphorylation	SGERSGRSGSSLYQV CCCCCCCCCCCCEEE	46.69	29978859
467	Phosphorylation	ERSGRSGSSLYQVST CCCCCCCCCCEEEEC	20.58	29978859
468	Phosphorylation	RSGRSGSSLYQVSTH CCCCCCCCCEEEECC	34.32	29978859
470	Phosphorylation	GRSGSSLYQVSTHEQ CCCCCCCEEEECCCC	14.60	29978859
473	Phosphorylation	GSSLYQVSTHEQPDS CCCCEEEECCCCCCC	14.44	29978859
474	Phosphorylation	SSLYQVSTHEQPDSA CCCEEEECCCCCCCC	30.49	29978859
480	Phosphorylation	STHEQPDSAHGRTGT ECCCCCCCCCCCCCC	28.93	29978859
504	Phosphorylation	HEQARDSSRHSASQE HHHHHHCCCCCCHHH	38.00	24706070
507	Phosphorylation	ARDSSRHSASQEGQD HHHCCCCCCHHHCCC	28.62	27966365
509	Phosphorylation	DSSRHSASQEGQDTI HCCCCCCHHHCCCCC	31.60	24706070
515	Phosphorylation	ASQEGQDTIRGHPGS CHHHCCCCCCCCCCC	12.51	-
535	Phosphorylation	QGSHHEQSVNRSGHS CCCCCCCCCCCCCCC	20.55	-
542	Phosphorylation	SVNRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
547	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
562	Phosphorylation	SDASHGQSGSRSASR CCCCCCCCCCCCCCC	43.24	-
581	Phosphorylation	EEQSGDGTRHSGSRH CHHCCCCCCCCCCCC	29.92	-
586	Phosphorylation	DGTRHSGSRHHEASS CCCCCCCCCCCCCCC	31.30	-
620	Phosphorylation	TSRNQGSSVSQDSDS CCCCCCCCCCCCCCC	32.39	22210691
622	Phosphorylation	RNQGSSVSQDSDSQG CCCCCCCCCCCCCCC	30.16	-
625	Phosphorylation	GSSVSQDSDSQGHSE CCCCCCCCCCCCCCC	31.37	30576142
631	Phosphorylation	DSDSQGHSEDSERWS CCCCCCCCCCCCCCC	50.34	22210691
634	Phosphorylation	SQGHSEDSERWSGSA CCCCCCCCCCCCCCC	25.63	22210691
638	Phosphorylation	SEDSERWSGSASRNH CCCCCCCCCCCCCCC	29.14	-
640	Phosphorylation	DSERWSGSASRNHHG CCCCCCCCCCCCCCC	19.97	-
642	Phosphorylation	ERWSGSASRNHHGSA CCCCCCCCCCCCCCH	35.00	-
648	Phosphorylation	ASRNHHGSAQEQSRD CCCCCCCCHHHCCCC	23.56	-
653	Phosphorylation	HGSAQEQSRDGSRHP CCCHHHCCCCCCCCC	31.42	30576142
676	Phosphorylation	GHGHSADSSRKSGTR CCCCCCCCCCCCCCC	31.59	28258704
682	Phosphorylation	DSSRKSGTRHTQNSS CCCCCCCCCCCCCCC	26.77	28258704
702	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
716	Phosphorylation	GSRHQLQSADSSRHS CCHHHHHCCCCCCCC	42.51	17494752
732	Phosphorylation	TGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	22817900
790	Phosphorylation	SGERSRRSGSFLYQV CCCCHHHHCCEEEEE	37.36	28348404
792	Phosphorylation	ERSRRSGSFLYQVST CCHHHHCCEEEEEEE	17.21	28348404
795	Phosphorylation	RRSGSFLYQVSTHKQ HHHCCEEEEEEECCC	12.59	-
832	Phosphorylation	ARDNSRHSASQDGQD HHCCCCCCCCCCCCC	28.62	20639409
834	Phosphorylation	DNSRHSASQDGQDTI CCCCCCCCCCCCCCC	31.64	20639409
847	Phosphorylation	TIRGHPGSSRRGRQG CCCCCCCCCCCCCCC	25.73	-
848	Phosphorylation	IRGHPGSSRRGRQGS CCCCCCCCCCCCCCC	31.73	-
860	Phosphorylation	QGSHHEQSVDRSGHS CCCCCCCCCCCCCCC	24.01	28355574
867	Phosphorylation	SVDRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
872	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
944	Phosphorylation	RTSRRQGSSVSQDSD CCCCCCCCCCCCCCC	21.16	-
945	Phosphorylation	TSRRQGSSVSQDSDS CCCCCCCCCCCCCCC	32.39	-
950	Phosphorylation	GSSVSQDSDSEGHSE CCCCCCCCCCCCCCC	35.09	-
956	Phosphorylation	DSDSEGHSEDSERWS CCCCCCCCCCCHHCC	54.69	-
959	Phosphorylation	SEGHSEDSERWSGSA CCCCCCCCHHCCCCC	25.63	-
963	Phosphorylation	SEDSERWSGSASRNH CCCCHHCCCCCCCCC	29.14	-
982	Phosphorylation	QEQSRHGSRHPRSHH HHHHHCCCCCCCCCC	22.69	-
1012	Phosphorylation	SGTPHAETSSGGQAA CCCCCCCCCCCCCCC	29.04	-
1013	Phosphorylation	GTPHAETSSGGQAAS CCCCCCCCCCCCCCC	20.63	-
1014	Phosphorylation	TPHAETSSGGQAASS CCCCCCCCCCCCCCH	55.13	-
1020	Phosphorylation	SSGGQAASSHEQARS CCCCCCCCHHHHHHC	34.93	-
1021	Phosphorylation	SGGQAASSHEQARSS CCCCCCCHHHHHHCC	26.73	-
1027	Phosphorylation	SSHEQARSSPGERHG CHHHHHHCCCCCCCC	43.85	26699800
1028	Phosphorylation	SHEQARSSPGERHGS HHHHHHCCCCCCCCC	31.22	26699800
1040	Phosphorylation	HGSRHQQSADSSRHS CCCCCCCCHHHHCCC	27.72	29978859
1043	Phosphorylation	RHQQSADSSRHSGIP CCCCCHHHHCCCCCC	29.05	29978859
1044	Phosphorylation	HQQSADSSRHSGIPR CCCCHHHHCCCCCCH	34.26	29978859
1055	Phosphorylation	GIPRRQASSAVRDSG CCCHHHHHHCHHCCC	15.53	-
1114	Phosphorylation	SGGRSGRSGSFIYQV CCCCCCCCCEEEEEE	42.17	27966365
1116	Phosphorylation	GRSGRSGSFIYQVST CCCCCCCEEEEEEEC	15.09	28857561
1119	Phosphorylation	GRSGSFIYQVSTHEQ CCCCEEEEEEECCCC	10.80	-
1122	Phosphorylation	GSFIYQVSTHEQSES CEEEEEEECCCCCHH	14.44	-
1123	Phosphorylation	SFIYQVSTHEQSESA EEEEEEECCCCCHHC	30.49	-
1153	Phosphorylation	HEQARDSSRHSASQE HHHHHHHHCCCCHHH	38.00	24706070
1156	Phosphorylation	ARDSSRHSASQEGQD HHHHHCCCCHHHCCC	28.62	27966365
1158	Phosphorylation	DSSRHSASQEGQDTI HHHCCCCHHHCCCCH	31.60	24706070
1164	Phosphorylation	ASQEGQDTIRAHPGS CHHHCCCCHHCCCCC	12.41	-
1184	Phosphorylation	QGSHHEQSVDRSGHS CCCCCCCCCCCCCCC	24.01	28355574
1191	Phosphorylation	SVDRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
1196	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
1211	Phosphorylation	SDASHGQSGSRSASR CCCCCCCCCCCCCCC	43.24	-
1230	Phosphorylation	DKQSGDGSRHSGSRH CCCCCCCCCCCCCCH	31.40	-
1233	Phosphorylation	SGDGSRHSGSRHHEA CCCCCCCCCCCHHHH	37.04	-
1235	Phosphorylation	DGSRHSGSRHHEAAS CCCCCCCCCHHHHHH	31.30	-
1250	Phosphorylation	WADSSRHSQVGQEQS HHCCCCCCCCCCCCC	26.00	-
1260	Phosphorylation	GQEQSSGSRTSRHQG CCCCCCCCCCCCCCC	34.04	21955146
1283	Phosphorylation	SERHSDDSERLSGSA CHHCCCCHHHHCCCC	29.61	-
1331	Phosphorylation	DSSRQSGTHHTESSS CCCCCCCCCCCCCCC	18.74	-
1336	Phosphorylation	SGTHHTESSSHGQAV CCCCCCCCCCCCCCC	37.99	22210691
1344	Phosphorylation	SSHGQAVSSHEQARS CCCCCCCCCHHHHHC	29.06	22210691
1351	Phosphorylation	SSHEQARSSPGERHG CCHHHHHCCCCCCCC	43.85	26699800
1352	Phosphorylation	SHEQARSSPGERHGS CHHHHHCCCCCCCCC	31.22	26699800
1364	Phosphorylation	HGSRHQQSADSSRHS CCCCCCCCHHCCCCC	27.72	29978859
1367	Phosphorylation	RHQQSADSSRHSGIG CCCCCHHCCCCCCCC	29.05	29978859
1368	Phosphorylation	HQQSADSSRHSGIGH CCCCHHCCCCCCCCC	34.26	29978859
1437	Methylation	QSGESSGRSRSFLYQ CCCCCCCCCHHHEEE	30.74	-
1443	Phosphorylation	GRSRSFLYQVSSHEQ CCCHHHEEEECCCCC	12.59	-
1468	Phosphorylation	STGGRQGSRHEQARN CCCCCCCCHHHHHHH	23.33	28787133
1480	Phosphorylation	ARNSSRHSASQDGQD HHHHHCCCCCCCCCC	28.62	20639409
1482	Phosphorylation	NSSRHSASQDGQDTI HHHCCCCCCCCCCCC	31.64	20639409
1535	Phosphorylation	SDASHGQSGPRSASR CCCCCCCCCCCCCCC	56.19	-
1554	Phosphorylation	EEQSGDGSRHSGSRH HHHCCCCCCCCCCCC	31.40	-
1555	Methylation	EQSGDGSRHSGSRHH HHCCCCCCCCCCCCC	33.26	-
1557	Phosphorylation	SGDGSRHSGSRHHEP CCCCCCCCCCCCCCC	37.04	-
1559	Phosphorylation	DGSRHSGSRHHEPST CCCCCCCCCCCCCCC	31.30	-
1586	Phosphorylation	GESAGSKTSRRQGSS CCCCCCCCCCCCCCC	29.21	-
1587	Phosphorylation	ESAGSKTSRRQGSSV CCCCCCCCCCCCCCC	29.24	-
1630	Phosphorylation	REQSRHGSRNPRSHQ HHHHHCCCCCCCCHH	23.82	-
1642	Phosphorylation	SHQEDRASHGHSAES CHHHHHHHCCCCHHH	30.78	-
1653	Phosphorylation	SAESSRQSGTRHAET CHHHHHCCCCCEEEC	40.81	-
1660	Phosphorylation	SGTRHAETSSGGQAA CCCCEEECCCCCCCC	29.04	-
1661	Phosphorylation	GTRHAETSSGGQAAS CCCEEECCCCCCCCC	20.63	-
1662	Phosphorylation	TRHAETSSGGQAASS CCEEECCCCCCCCCH	55.13	-
1668	Phosphorylation	SSGGQAASSQEQARS CCCCCCCCHHHHHHC	35.25	-
1669	Phosphorylation	SGGQAASSQEQARSS CCCCCCCHHHHHHCC	32.77	-
1675	Phosphorylation	SSQEQARSSPGERHG CHHHHHHCCCCCCCC	43.85	26699800
1676	Phosphorylation	SQEQARSSPGERHGS HHHHHHCCCCCCCCC	31.22	26699800
1691	Phosphorylation	RHQQSADSSTDSGTG CCCCCCCCCCCCCCC	34.55	22468782
1703	Phosphorylation	GTGRRQDSSVVGDSG CCCCCCCCCCCCCCC	19.39	-
1762	Phosphorylation	SGERSGRSGSFLYQV CCCCCCCCCCEEEEE	42.17	22777824
1764	Phosphorylation	ERSGRSGSFLYQVST CCCCCCCCEEEEEEC	17.21	30576142
1767	Phosphorylation	GRSGSFLYQVSTHEQ CCCCCEEEEEECCCC	12.59	-
1770	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEECCCCCCC	14.44	28348404
1771	Phosphorylation	SFLYQVSTHEQSESA CEEEEEECCCCCCCC	30.49	28348404
1777	Phosphorylation	STHEQSESAHGRTGP ECCCCCCCCCCCCCC	30.71	30576142
1782	Phosphorylation	SESAHGRTGPSTGGR CCCCCCCCCCCCCCC	59.02	30576142
1801	Phosphorylation	HEQARDSSRHSASQE HHHHHHHHCCCCHHH	38.00	24706070
1804	Phosphorylation	ARDSSRHSASQEGQD HHHHHCCCCHHHCCC	28.62	27966365
1806	Phosphorylation	DSSRHSASQEGQDTI HHHCCCCHHHCCCCC	31.60	24706070
1812	Phosphorylation	ASQEGQDTIRGHPGS CHHHCCCCCCCCCCC	12.51	-
1827	Phosphorylation	SRGGRQGSHYEQSVD CCCCCCCCCCCCCCC	17.98	-
1881	Phosphorylation	SGDGSRHSGSRHHEA CCCCCCCCCCCCCCH	37.04	-
1890	Phosphorylation	SRHHEASSRADSSRH CCCCCHHCCCCCCCC	38.24	30576142
1894	Phosphorylation	EASSRADSSRHSQVG CHHCCCCCCCCCCCC	28.43	-
1895	Phosphorylation	ASSRADSSRHSQVGQ HHCCCCCCCCCCCCC	34.26	30576142
1917	Phosphorylation	TSRNQGSSVSQDSDS CCCCCCCCCCCCCCC	32.39	22210691
1919	Phosphorylation	RNQGSSVSQDSDSQG CCCCCCCCCCCCCCC	30.16	-
1922	Phosphorylation	GSSVSQDSDSQGHSE CCCCCCCCCCCCCCC	31.37	-
1928	Phosphorylation	DSDSQGHSEDSERWS CCCCCCCCCCCHHHC	50.34	22210691
1931	Phosphorylation	SQGHSEDSERWSGSA CCCCCCCCHHHCCCC	25.63	22210691
1935	Phosphorylation	SEDSERWSGSASRNH CCCCHHHCCCCCHHC	29.14	-
1937	Phosphorylation	DSERWSGSASRNHLG CCHHHCCCCCHHCHH	19.97	30576142
1950	Phosphorylation	LGSAWEQSRDGSRHP HHHHHHHCCCCCCCC	22.33	30576142
1954	Phosphorylation	WEQSRDGSRHPGSHH HHHCCCCCCCCCCCC	31.53	-
1974	Phosphorylation	HGHSADSSRQSGTRH CCCCCCCCCCCCCCC	34.58	-
1977	Phosphorylation	SADSSRQSGTRHTES CCCCCCCCCCCCCCC	40.81	30576142
1982	Phosphorylation	RQSGTRHTESSSRGQ CCCCCCCCCCCCCCC	33.98	25852190
1984	Phosphorylation	SGTRHTESSSRGQAA CCCCCCCCCCCCCCC	34.47	25852190
1985	Phosphorylation	GTRHTESSSRGQAAS CCCCCCCCCCCCCCH	20.16	25852190
1986	Phosphorylation	TRHTESSSRGQAASS CCCCCCCCCCCCCHH	50.11	25852190
1992	Phosphorylation	SSRGQAASSHEQARS CCCCCCCHHHHHHHH	39.01	30576142
1999	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
2000	Phosphorylation	SHEQARSSAGERHGS HHHHHHHHHCCCCCC	34.44	30576142
2013	Phosphorylation	GSHHQLQSADSSRHS CCHHHCCCCCCCCCC	42.51	17494752
2020	Phosphorylation	SADSSRHSGIGHGQA CCCCCCCCCCCCCCH	30.88	20068231
2028	Phosphorylation	GIGHGQASSAVRDSG CCCCCCHHHCCCCCC	15.79	20068231
2029	Phosphorylation	IGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	20068231
2034	Phosphorylation	ASSAVRDSGHRGYSG HHHCCCCCCCCCCCC	26.40	-
2045	Phosphorylation	GYSGSQASDSEGHSE CCCCCCCCCCCCCCC	33.75	30576142
2047	Phosphorylation	SGSQASDSEGHSEDS CCCCCCCCCCCCCCC	42.87	-
2051	Phosphorylation	ASDSEGHSEDSDTQS CCCCCCCCCCCCCCC	54.69	30576142
2060	Phosphorylation	DSDTQSVSAQGKAGP CCCCCCCCCCCCCCC	21.81	24260401
2071	Phosphorylation	KAGPHQQSHKESARG CCCCCCCCCCHHHCC	29.92	30576142
2086	Methylation	QSGESSGRSGSFLYQ CCCCCCCCCCCEEEE	39.53	-
2087	Phosphorylation	SGESSGRSGSFLYQV CCCCCCCCCCEEEEE	42.17	-
2092	Phosphorylation	GRSGSFLYQVSTHEQ CCCCCEEEEEECCCC	12.59	-
2095	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEECCCCCCC	14.44	-
2126	Phosphorylation	YDQAQDSSRHSASQE CCCCCCCCCCCCCCC	42.15	24706070
2129	Phosphorylation	AQDSSRHSASQEGQD CCCCCCCCCCCCCCC	28.62	27966365
2131	Phosphorylation	DSSRHSASQEGQDTI CCCCCCCCCCCCCCC	31.60	24706070
2137	Phosphorylation	ASQEGQDTIRGHPGP CCCCCCCCCCCCCCC	12.51	-
2164	Phosphorylation	SVDRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
2169	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
2199	Phosphorylation	KTYDKEQSGDGSRHS CCCCCHHCCCCCCCC	39.69	-
2203	Phosphorylation	KEQSGDGSRHSGSHH CHHCCCCCCCCCCCC	31.40	-
2208	Phosphorylation	DGSRHSGSHHHEASS CCCCCCCCCCCCHHH	23.74	-
2223	Phosphorylation	WADSSRHSLVGQGQS HCCCCCCCCCCCCCC	24.52	24719451
2235	Phosphorylation	GQSSGPRTSRPRGSS CCCCCCCCCCCCCCC	32.02	24719451
2241	Phosphorylation	RTSRPRGSSVSQDSD CCCCCCCCCCCCCCC	28.92	-
2242	Phosphorylation	TSRPRGSSVSQDSDS CCCCCCCCCCCCCCC	28.72	30576142
2247	Phosphorylation	GSSVSQDSDSEGHSE CCCCCCCCCCCCCCC	35.09	30576142
2249	Phosphorylation	SVSQDSDSEGHSEDS CCCCCCCCCCCCCCH	49.80	30576142
2253	Phosphorylation	DSDSEGHSEDSERRS CCCCCCCCCCHHCCC	54.69	-
2256	Phosphorylation	SEGHSEDSERRSGSA CCCCCCCHHCCCCCC	29.02	-
2260	Phosphorylation	SEDSERRSGSASRNH CCCHHCCCCCCCCCC	43.23	-
2262	Phosphorylation	DSERRSGSASRNHHG CHHCCCCCCCCCCCC	25.07	-
2264	Phosphorylation	ERRSGSASRNHHGSA HCCCCCCCCCCCCCH	35.00	-
2270	Phosphorylation	ASRNHHGSAQEQSRD CCCCCCCCHHHCCCC	23.56	-
2310	Phosphorylation	GTHHAENSSGGQAAS CCCCCCCCCCCCCCH	23.12	22210691
2311	Phosphorylation	THHAENSSGGQAASS CCCCCCCCCCCCCHH	59.53	22210691
2317	Phosphorylation	SSGGQAASSHEQARS CCCCCCCHHHHHHHH	34.93	-
2318	Phosphorylation	SGGQAASSHEQARSS CCCCCCHHHHHHHHH	26.73	-
2324	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
2344	Phosphorylation	SADSSRHSGIGHGQA CCCCCCCCCCCCCCH	30.88	20068231
2352	Phosphorylation	GIGHGQASSAVRDSG CCCCCCHHHCCCCCC	15.79	20068231
2353	Phosphorylation	IGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	20068231
2371	Phosphorylation	SGSQASDSEGHSEDS CCCCCCCCCCCCCCC	42.87	-
2411	Phosphorylation	SAGRSGRSGSFLYQV CCCCCCCCCCEEEEE	42.17	22777824
2413	Phosphorylation	GRSGRSGSFLYQVST CCCCCCCCEEEEEEC	17.21	26699800
2416	Phosphorylation	GRSGSFLYQVSTHEQ CCCCCEEEEEECCCC	12.59	-
2419	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEECCCCCCC	14.44	28348404
2420	Phosphorylation	SFLYQVSTHEQSESA CEEEEEECCCCCCCC	30.49	28348404
2476	Phosphorylation	SSGGRQGSHYEQLVD CCCCCCCCCHHHHHC	17.98	-
2485	Phosphorylation	YEQLVDRSGHSGSHH HHHHHCCCCCCCCCC	36.07	22468782
2493	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
2495	Phosphorylation	SGSHHSHTTSQGRSD CCCCCCCCCCCCCCC	31.02	22468782
2496	Phosphorylation	GSHHSHTTSQGRSDA CCCCCCCCCCCCCCC	17.40	22468782
2514	Phosphorylation	HSGSRSASRQTRNDE CCCCCCCCCCCCCCC	26.60	17924679
2517	Phosphorylation	SRSASRQTRNDEQSG CCCCCCCCCCCCCCC	30.26	17924679
2528	Methylation	EQSGDGSRHSGSRHH CCCCCCCCCCCCCCC	33.26	-
2530	Phosphorylation	SGDGSRHSGSRHHEA CCCCCCCCCCCCCCH	37.04	-
2538	Phosphorylation	GSRHHEASSRADSSG CCCCCCHHCCCCCCC	19.85	-
2544	Phosphorylation	ASSRADSSGHSQVGQ HHCCCCCCCCCCCCC	40.86	-
2559	Phosphorylation	GQSEGPRTSRNWGSS CCCCCCCCCCCCCCC	34.86	-
2560	Phosphorylation	QSEGPRTSRNWGSSF CCCCCCCCCCCCCCC	25.54	-
2566	Phosphorylation	TSRNWGSSFSQDSDS CCCCCCCCCCCCCCC	25.61	-
2568	Phosphorylation	RNWGSSFSQDSDSQG CCCCCCCCCCCCCCC	34.72	-
2571	Phosphorylation	GSSFSQDSDSQGHSE CCCCCCCCCCCCCCC	31.37	-
2584	Phosphorylation	SEDSERWSGSASRNH CCCCCCCCCCCCCCC	29.14	-
2586	Phosphorylation	DSERWSGSASRNHHG CCCCCCCCCCCCCCC	19.97	-
2588	Phosphorylation	ERWSGSASRNHHGSA CCCCCCCCCCCCCCH	35.00	-
2594	Phosphorylation	ASRNHHGSAQEQLRD CCCCCCCCHHHHHCC	23.56	20068231
2623	Phosphorylation	HGHSADSSRQSGTRH CCCCCCCCCCCCCCC	34.58	-
2641	Phosphorylation	SSGGQAASSHEQARS CCCCCCCHHHHHHHH	34.93	-
2642	Phosphorylation	SGGQAASSHEQARSS CCCCCCHHHHHHHHH	26.73	-
2648	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
2668	Phosphorylation	SADSSRHSGIGHGQA CCCCCCCCCCCCCCH	30.88	20068231
2676	Phosphorylation	GIGHGQASSAVRDSG CCCCCCHHHCCCCCC	15.79	20068231
2677	Phosphorylation	IGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	20068231
2682	Phosphorylation	ASSAVRDSGHRGYSG HHHCCCCCCCCCCCC	26.40	-
2737	Phosphorylation	ETSGHSGSFLYQVST CCCCCCCCEEEEEEE	18.32	-
2740	Phosphorylation	GHSGSFLYQVSTHEQ CCCCCEEEEEEECCC	12.59	-
2743	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEEECCCCCC	14.44	-
2777	Phosphorylation	AQDSSRHSASQDGQD HHCHHCCCCCCCCCC	28.62	20639409
2779	Phosphorylation	DSSRHSASQDGQDTI CHHCCCCCCCCCCCC	31.64	20639409
2817	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
2851	Phosphorylation	EEQSGDGSRHSGSRH HHHCCCCCCCCCCCC	31.40	-
2852	Methylation	EQSGDGSRHSGSRHH HHCCCCCCCCCCCCC	33.26	-
2854	Phosphorylation	SGDGSRHSGSRHHEA CCCCCCCCCCCCCCH	37.04	22210691
2856	Phosphorylation	DGSRHSGSRHHEAST CCCCCCCCCCCCHHC	31.30	-
2871	Phosphorylation	HADISRHSQAVQGQS HHHHHHHHHHHHCCC	20.80	20860994
2889	Phosphorylation	RRSRRQGSSVSQDSD CCHHCCCCCCCCCCC	21.16	-
2890	Phosphorylation	RSRRQGSSVSQDSDS CHHCCCCCCCCCCCC	32.39	-
2895	Phosphorylation	GSSVSQDSDSEGHSE CCCCCCCCCCCCCCC	35.09	-
2901	Phosphorylation	DSDSEGHSEDSERWS CCCCCCCCCCCCCCC	54.69	-
2904	Phosphorylation	SEGHSEDSERWSGSA CCCCCCCCCCCCCCC	25.63	-
2908	Phosphorylation	SEDSERWSGSASRNH CCCCCCCCCCCCCCC	29.14	-
2910	Phosphorylation	DSERWSGSASRNHHG CCCCCCCCCCCCCCC	19.97	-
2912	Phosphorylation	ERWSGSASRNHHGSA CCCCCCCCCCCCCCH	35.00	-
2918	Phosphorylation	ASRNHHGSAQEQLRD CCCCCCCCHHHHHCC	23.56	20068231
2947	Phosphorylation	HGHSADSSRQSGTRH CCCCCCCCCCCCCCC	34.58	-
2965	Phosphorylation	SSGGQAASSHEQARS CCCCCCCHHHHHHHH	34.93	-
2966	Phosphorylation	SGGQAASSHEQARSS CCCCCCHHHHHHHHH	26.73	-
2972	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
2992	Phosphorylation	SADSSRHSGIGHGQA CCCCCCCCCCCCCCH	30.88	20068231
3000	Phosphorylation	GIGHGQASSAVRDSG CCCCCCHHHCCCCCC	15.79	20068231
3001	Phosphorylation	IGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	20068231
3006	Phosphorylation	ASSAVRDSGHRGYSG HHHCCCCCCCCCCCC	26.40	-
3061	Phosphorylation	ETSGHSGSFLYQVST CCCCCCCCEEEEEEE	18.32	-
3064	Phosphorylation	GHSGSFLYQVSTHEQ CCCCCEEEEEEECCC	12.59	-
3067	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEEECCCCCC	14.44	-
3098	Phosphorylation	HEQAQDSSRHSASQY HHHHHHCCCCCHHHH	42.15	22210691
3101	Phosphorylation	AQDSSRHSASQYGQD HHHCCCCCHHHHCCC	28.62	22210691
3103	Phosphorylation	DSSRHSASQYGQDTI HCCCCCHHHHCCCCC	27.27	22210691
3141	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
3195	Phosphorylation	HADISRHSQAVQGQS HHHHHHHHHHHHCCC	20.80	20860994
3213	Phosphorylation	RRSRRQGSSVSQDSD CCHHCCCCCCCCCCC	21.16	-
3214	Phosphorylation	RSRRQGSSVSQDSDS CHHCCCCCCCCCCCC	32.39	-
3219	Phosphorylation	GSSVSQDSDSEGHSE CCCCCCCCCCCCCCC	35.09	-
3225	Phosphorylation	DSDSEGHSEDSERWS CCCCCCCCCCCHHCC	54.69	-
3228	Phosphorylation	SEGHSEDSERWSGSA CCCCCCCCHHCCCCC	25.63	-
3232	Phosphorylation	SEDSERWSGSASRNH CCCCHHCCCCCCCCC	29.14	-
3251	Phosphorylation	QEQSRHGSRHPRSHH HHHHCCCCCCCCCCC	22.69	-
3274	Phosphorylation	SADRSRQSGTRHAET CCHHHCCCCCCCEEC	40.81	-
3281	Phosphorylation	SGTRHAETSSGGQAA CCCCCEECCCCCCCC	29.04	-
3282	Phosphorylation	GTRHAETSSGGQAAS CCCCEECCCCCCCCC	20.63	-
3283	Phosphorylation	TRHAETSSGGQAASS CCCEECCCCCCCCCH	55.13	-
3289	Phosphorylation	SSGGQAASSHEQARS CCCCCCCCHHHHHHC	34.93	-
3290	Phosphorylation	SGGQAASSHEQARSS CCCCCCCHHHHHHCC	26.73	-
3296	Phosphorylation	SSHEQARSSPGERHG CHHHHHHCCCCCCCC	43.85	26699800
3297	Phosphorylation	SHEQARSSPGERHGS HHHHHHCCCCCCCCC	31.22	26699800
3309	Phosphorylation	HGSRHQQSADSSRHS CCCCCCCCCCCCCCC	27.72	29978859
3312	Phosphorylation	RHQQSADSSRHSGIP CCCCCCCCCCCCCCC	29.05	29978859
3313	Phosphorylation	HQQSADSSRHSGIPR CCCCCCCCCCCCCCC	34.26	29978859
3316	Phosphorylation	SADSSRHSGIPRGQA CCCCCCCCCCCCCCH	36.99	-
3335	Phosphorylation	RDSRHWGSSGSQASD HCCCCCCCCCCCCCC	26.74	30576142
3336	Phosphorylation	DSRHWGSSGSQASDS CCCCCCCCCCCCCCC	38.23	30576142
3367	Phosphorylation	QAGPHQQSHQESARD CCCCCHHCCCHHHCC	22.14	30576142
3383	Phosphorylation	SGGRSGRSGSFLYQV CCCCCCCCCCEEEEE	42.17	22777824
3385	Phosphorylation	GRSGRSGSFLYQVST CCCCCCCCEEEEEEC	17.21	26699800
3388	Phosphorylation	GRSGSFLYQVSTHEQ CCCCCEEEEEECCCC	12.59	-
3391	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEECCCCCCC	14.44	28348404
3392	Phosphorylation	SFLYQVSTHEQSESA CEEEEEECCCCCCCC	30.49	28348404
3422	Phosphorylation	HEQARDSSRHSASQE HHHHHHHHCCCCHHH	38.00	24706070
3425	Phosphorylation	ARDSSRHSASQEGQD HHHHHCCCCHHHCCC	28.62	27966365
3427	Phosphorylation	DSSRHSASQEGQDTI HHHCCCCHHHCCCCC	31.60	24706070
3433	Phosphorylation	ASQEGQDTIRGHPGS CHHHCCCCCCCCCCC	12.51	-
3440	Phosphorylation	TIRGHPGSSRRGRQG CCCCCCCCCCCCCCC	25.73	-
3441	Phosphorylation	IRGHPGSSRRGRQGS CCCCCCCCCCCCCCC	31.73	-
3460	Phosphorylation	SVDRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
3465	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
3489	Phosphorylation	SRSASRQTRNDEQSG CCCCCCCCCCCCCCC	30.26	17924679
3510	Phosphorylation	WSHHHEASTQADSSR CHHCCCCCCCCCCCC	20.33	-
3511	Phosphorylation	SHHHEASTQADSSRH HHCCCCCCCCCCCCC	34.52	-
3515	Phosphorylation	EASTQADSSRHSQSG CCCCCCCCCCCCCCC	32.08	-
3516	Phosphorylation	ASTQADSSRHSQSGQ CCCCCCCCCCCCCCC	34.26	-
3538	Phosphorylation	TSRNQGSSVSQDSDS CCCCCCCCCCCCCCC	32.39	22210691
3540	Phosphorylation	RNQGSSVSQDSDSQG CCCCCCCCCCCCCCC	30.16	-
3543	Phosphorylation	GSSVSQDSDSQGHSE CCCCCCCCCCCCCCC	31.37	-
3549	Phosphorylation	DSDSQGHSEDSERWS CCCCCCCCCCCHHCC	50.34	22210691
3552	Phosphorylation	SQGHSEDSERWSGSA CCCCCCCCHHCCCCC	25.63	22210691
3556	Phosphorylation	SEDSERWSGSASRNH CCCCHHCCCCCCCCC	29.14	-
3606	Phosphorylation	GTHHAENSSGGQAAS CCCCCCCCCCCCCCH	23.12	22210691
3607	Phosphorylation	THHAENSSGGQAASS CCCCCCCCCCCCCHH	59.53	22210691
3613	Phosphorylation	SSGGQAASSHEQARS CCCCCCCHHHHHHHH	34.93	-
3614	Phosphorylation	SGGQAASSHEQARSS CCCCCCHHHHHHHHH	26.73	-
3620	Phosphorylation	SSHEQARSSAGERHG HHHHHHHHHHCCCCC	27.79	-
3640	Phosphorylation	SADSSRHSGIGHGQA CCCCCCCCCCCCCCH	30.88	20068231
3648	Phosphorylation	GIGHGQASSAVRDSG CCCCCCHHHCCCCCC	15.79	20068231
3649	Phosphorylation	IGHGQASSAVRDSGH CCCCCHHHCCCCCCC	33.52	20068231
3667	Phosphorylation	SGSQASDSEGHSEDS CCCCCCCCCCCCCCC	42.87	-
3707	Phosphorylation	SAGRSGRSGSFLYQV CCCCCCCCCCEEEEE	42.17	22777824
3709	Phosphorylation	GRSGRSGSFLYQVST CCCCCCCCEEEEEEC	17.21	26699800
3712	Phosphorylation	GRSGSFLYQVSTHEQ CCCCCEEEEEECCCC	12.59	-
3715	Phosphorylation	GSFLYQVSTHEQSES CCEEEEEECCCCCCC	14.44	28348404
3716	Phosphorylation	SFLYQVSTHEQSESA CEEEEEECCCCCCCC	30.49	28348404
3722	Phosphorylation	STHEQSESAHGRAGP ECCCCCCCCCCCCCC	30.71	22210691
3731	Phosphorylation	HGRAGPSTGGRQGSR CCCCCCCCCCCCCCH	46.95	22210691
3737	Phosphorylation	STGGRQGSRHEQARD CCCCCCCCHHHHHHH	23.33	-
3746	Phosphorylation	HEQARDSSRHSASQE HHHHHHHHCCCCHHH	38.00	24706070
3749	Phosphorylation	ARDSSRHSASQEGQD HHHHHCCCCHHHCCC	28.62	27966365
3751	Phosphorylation	DSSRHSASQEGQDTI HHHCCCCHHHCCCCC	31.60	24706070
3757	Phosphorylation	ASQEGQDTIRGHPGS CHHHCCCCCCCCCCC	12.51	-
3784	Phosphorylation	SVDRSGHSGSHHSHT CCCCCCCCCCCCCCC	45.58	-
3789	Phosphorylation	GHSGSHHSHTTSQGR CCCCCCCCCCCCCCC	19.66	-
3804	Phosphorylation	SDASHGQSGSRSASR CCCCCCCCCCCCCCC	43.24	-
3823	Phosphorylation	EEQSGDGSRHSGSRH HHHCCCCCCCCCCCC	31.40	-
3824	Methylation	EQSGDGSRHSGSRHH HHCCCCCCCCCCCCC	33.26	-
3826	Phosphorylation	SGDGSRHSGSRHHEA CCCCCCCCCCCCCCC	37.04	-
3828	Phosphorylation	DGSRHSGSRHHEAST CCCCCCCCCCCCCCH	31.30	-
3835	Phosphorylation	SRHHEASTQADSSRH CCCCCCCHHHCCCCC	34.52	-
3839	Phosphorylation	EASTQADSSRHSQSG CCCHHHCCCCCCCCC	32.08	30576142
3840	Phosphorylation	ASTQADSSRHSQSGQ CCHHHCCCCCCCCCC	34.26	30576142
3843	Phosphorylation	QADSSRHSQSGQGES HHCCCCCCCCCCCCC	25.57	-
3845	Phosphorylation	DSSRHSQSGQGESAG CCCCCCCCCCCCCCC	35.78	30576142
3850	Phosphorylation	SQSGQGESAGSRRSR CCCCCCCCCCCHHHH	44.76	-
3853	Phosphorylation	GQGESAGSRRSRRQG CCCCCCCCHHHHCCC	25.00	-
3861	Phosphorylation	RRSRRQGSSVSQDSD HHHHCCCCCCCCCCC	21.16	29083192
3862	Phosphorylation	RSRRQGSSVSQDSDS HHHCCCCCCCCCCCC	32.39	29083192
3864	Phosphorylation	RRQGSSVSQDSDSEA HCCCCCCCCCCCCCC	30.16	29083192
3867	Phosphorylation	GSSVSQDSDSEAYPE CCCCCCCCCCCCCCC	35.09	29083192
3869	Phosphorylation	SVSQDSDSEAYPEDS CCCCCCCCCCCCCCH	28.25	29083192
3872	Phosphorylation	QDSDSEAYPEDSERR CCCCCCCCCCCHHHH	11.78	29083192
3876	Phosphorylation	SEAYPEDSERRSESA CCCCCCCHHHHHHHH	31.20	29083192
3915	Phosphorylation	DTASHVQSSPVQSDS CCHHHHCCCCCCCCC	35.20	18691976
3938	Phosphorylation	FSSLSQDSAYHSGIQ CCCCCCCCHHCCCCC	24.08	-
3940	Phosphorylation	SLSQDSAYHSGIQSR CCCCCCHHCCCCCCC	10.64	-
3952	Phosphorylation	QSRGSPHSSSSYHYQ CCCCCCCCCCCCEEC	34.99	-
3958	Phosphorylation	HSSSSYHYQSEGTER CCCCCCEECCCCCCC	12.90	-
3984	Phosphorylation	GSYGSADYDYGESGF CCCCCCCCCCCCCCC	15.69	-
4001	Phosphorylation	SQHGSVSYNSNPVVF CCCCCCCCCCCCEEE	22.06	-
4012	Phosphorylation	PVVFKERSDICKASA CEEEEEHHHHHHHHH	32.21	22210691
4018	Phosphorylation	RSDICKASAFGKDHP HHHHHHHHHCCCCCC	15.04	-
4031	Phosphorylation	HPRYYATYINKDPGL CCCEEEEEECCCCCC	8.37	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FILA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FILA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FILA_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FILA_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 146700: Ichthyosis vulgaris (VI)
• 605803: Dermatitis atopic 2 (ATOD2)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2514 AND THR-2517, ANDMASS SPECTROMETRY.
PubMed: 17924679