| UniProt ID | HXB5_HUMAN | |
|---|---|---|
| UniProt AC | P09067 | |
| Protein Name | Homeobox protein Hox-B5 | |
| Gene Name | HOXB5 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 269 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. | |
| Protein Sequence | MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSSYFVNSF ------CCCCCCCCC | 33.47 | 25072903 | |
| 3 | Phosphorylation | -----MSSYFVNSFS -----CCCCCCCCCC | 22.69 | 25072903 | |
| 4 | Phosphorylation | ----MSSYFVNSFSG ----CCCCCCCCCCC | 12.30 | 25072903 | |
| 8 | Phosphorylation | MSSYFVNSFSGRYPN CCCCCCCCCCCCCCC | 18.58 | 25072903 | |
| 10 | Phosphorylation | SYFVNSFSGRYPNGP CCCCCCCCCCCCCCC | 23.37 | 25072903 | |
| 13 | Phosphorylation | VNSFSGRYPNGPDYQ CCCCCCCCCCCCCCE | 12.46 | 25072903 | |
| 19 | Phosphorylation | RYPNGPDYQLLNYGS CCCCCCCCEEEECCC | 12.28 | 25072903 | |
| 24 | Phosphorylation | PDYQLLNYGSGSSLS CCCEEEECCCCCCCC | 16.79 | 25072903 | |
| 26 | Phosphorylation | YQLLNYGSGSSLSGS CEEEECCCCCCCCCC | 25.74 | 25072903 | |
| 28 | Phosphorylation | LLNYGSGSSLSGSYR EEECCCCCCCCCCCC | 29.78 | 25072903 | |
| 29 | Phosphorylation | LNYGSGSSLSGSYRD EECCCCCCCCCCCCC | 30.04 | 25072903 | |
| 31 | Phosphorylation | YGSGSSLSGSYRDPA CCCCCCCCCCCCCCC | 27.86 | 25072903 | |
| 33 | Phosphorylation | SGSSLSGSYRDPAAM CCCCCCCCCCCCCHH | 17.39 | 25072903 | |
| 34 | Phosphorylation | GSSLSGSYRDPAAMH CCCCCCCCCCCCHHC | 23.66 | 25072903 | |
| 55 | Phosphorylation | NYNGMDLSVNRSSAS CCCCCEEEECCCCCC | 17.06 | - | |
| 90 | Phosphorylation | PRFRQAASSCSLSSP HHHHHHHHHCCCCCC | 34.59 | 24043423 | |
| 91 | Phosphorylation | RFRQAASSCSLSSPE HHHHHHHHCCCCCCC | 11.73 | 24043423 | |
| 93 | Phosphorylation | RQAASSCSLSSPESL HHHHHHCCCCCCCCC | 32.98 | 24043423 | |
| 95 | Phosphorylation | AASSCSLSSPESLPC HHHHCCCCCCCCCCC | 27.79 | 24043423 | |
| 96 | Phosphorylation | ASSCSLSSPESLPCT HHHCCCCCCCCCCCC | 37.67 | 24043423 | |
| 99 | Phosphorylation | CSLSSPESLPCTNGD CCCCCCCCCCCCCCC | 40.78 | 24043423 | |
| 103 | Phosphorylation | SPESLPCTNGDSHGA CCCCCCCCCCCCCCC | 40.05 | 24043423 | |
| 107 | Phosphorylation | LPCTNGDSHGAKPSA CCCCCCCCCCCCCCC | 25.81 | 24043423 | |
| 186 | Phosphorylation | WMRKLHISHDMTGPD HHHHHCCCCCCCCCC | 11.59 | 24719451 | |
| 199 | Phosphorylation | PDGKRARTAYTRYQT CCCHHCCCCHHHHHH | 24.03 | - | |
| 201 | Phosphorylation | GKRARTAYTRYQTLE CHHCCCCHHHHHHHH | 7.37 | - | |
| 202 | Phosphorylation | KRARTAYTRYQTLEL HHCCCCHHHHHHHHH | 22.04 | - | |
| 211 | Ubiquitination | YQTLELEKEFHFNRY HHHHHHHHHHHHHHH | 77.60 | 21890473 | |
| 217 | Methylation | EKEFHFNRYLTRRRR HHHHHHHHHHHHHHH | 27.22 | - | |
| 218 | Phosphorylation | KEFHFNRYLTRRRRI HHHHHHHHHHHHHHH | 17.33 | - | |
| 257 | Phosphorylation | KKDNKLKSMSLATAG CCCCCCHHCCCCCCC | 24.84 | - | |
| 259 | Phosphorylation | DNKLKSMSLATAGSA CCCCHHCCCCCCCCC | 23.18 | - | |
| 262 | Phosphorylation | LKSMSLATAGSAFQP CHHCCCCCCCCCCCC | 36.52 | 22210691 | |
| 265 | Phosphorylation | MSLATAGSAFQP--- CCCCCCCCCCCC--- | 24.36 | 22210691 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HXB5_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HXB5_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HXB5_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
