ERIC5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERIC5_HUMAN
• UniProt AC: Q6P6B1
• Protein Name: Glutamate-rich protein 5
• Gene Name: ERICH5
• Organism: Homo sapiens (Human).
• Sequence Length: 374
• Protein Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRNIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	GDSSRFPSVTSNEHF CCCCCCCCCCCCCCC		30108239
21	Phosphorylation	SSRFPSVTSNEHFST CCCCCCCCCCCCCCC		30576142
22	Phosphorylation	SRFPSVTSNEHFSTA CCCCCCCCCCCCCCH		30108239
27	Phosphorylation	VTSNEHFSTAEESES CCCCCCCCCHHHHHH		30108239
28	Phosphorylation	TSNEHFSTAEESESC CCCCCCCCHHHHHHH		30108239
49	Phosphorylation	HALGRESTVDGNVQR CCCCCCCCCCCCCCC		-
77	Ubiquitination	EPTANGVKPLQEQPL CCCCCCCCCCCCCCC		21906983
138	Phosphorylation	KKDAGAGTEAESLKG CCCCCCCCCHHHHCC		26657352
142	Phosphorylation	GAGTEAESLKGNAEA CCCCCHHHHCCCCCC		22985185
169	Phosphorylation	QAAVEKDSLRAVEVT CHHHHHHCCCEEEEC		26657352
274	Phosphorylation	TPEVLDRSQLVEKPV CHHHHCHHHHCCCCC		22210691
307	Phosphorylation	QPEGIVGSMEHPARN CCCCCCCCCCCCCCC		28985074
320	Phosphorylation	RNVEAGAYVEMIRNI CCCCHHHHHHHHHHC		28796482
346	Phosphorylation	ETGEKVETDMENEKV CCCCCEEHHHCCCCC		26471730
354	Phosphorylation	DMENEKVSEGAETKE HHCCCCCCCCCCCCC		26471730
359	Phosphorylation	KVSEGAETKEEETGE CCCCCCCCCCHHCCC		26471730
364	Phosphorylation	AETKEEETGEVVDLS CCCCCHHCCCEEECC		28258704
371	Phosphorylation	TGEVVDLSAAT---- CCCEEECCCCC----		26471730
374	Phosphorylation	VVDLSAAT------- EEECCCCC-------		28258704

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERIC5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERIC5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERIC5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ERIC5_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.