UBTD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UBTD2_HUMAN
• UniProt AC: Q8WUN7
• Protein Name: Ubiquitin domain-containing protein 2
• Gene Name: UBTD2
• Organism: Homo sapiens (Human).
• Sequence Length: 234
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MGGCVGAQHDSSGSLNENSEGTGVALGRNQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGYECQLRLRLSTGKDLKLVVRSTDTVFHMKRRLHAAEGVEPGSQRWFFSGRPLTDKMKFEELKIPKDYVVQVIVSQPVQNPTPVEN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	SGSLNENSEGTGVAL CCCCCCCCCCCCEEC	31.09	24275569
40	Ubiquitination	KKEKPKWKSDYPMTD CCCCCCCCCCCCCCC	39.31	21890473
43	Phosphorylation	KPKWKSDYPMTDGQL CCCCCCCCCCCCCCH	11.29	-
46	Phosphorylation	WKSDYPMTDGQLRSK CCCCCCCCCCCHHCC	32.26	-
53	Ubiquitination	TDGQLRSKRDEFWDT CCCCHHCCCHHHHHC	58.39	21890473
68	Ubiquitination	APAFEGRKEIWDALK CCCCCCHHHHHHHHH	65.49	21890473
165	Ubiquitination	LSTGKDLKLVVRSTD ECCCCCCEEEEECCC	49.74	-
211	Ubiquitination	KMKFEELKIPKDYVV CCCHHHCCCCCCEEE	61.31	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UBTD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UBTD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UBTD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBC_HUMAN	UBC	physical	20440844
UBA1_HUMAN	UBA1	physical	25207809
UBP5_HUMAN	USP5	physical	25207809
UBC_HUMAN	UBC	physical	25207809
GALT_HUMAN	GALT	physical	26186194
CYTN_HUMAN	CST1	physical	26186194
CYTS_HUMAN	CST4	physical	26186194
SMR3B_HUMAN	SMR3B	physical	26186194
GALT_HUMAN	GALT	physical	28514442
SMR3B_HUMAN	SMR3B	physical	28514442
CYTN_HUMAN	CST1	physical	28514442
CYTS_HUMAN	CST4	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.