GALT_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GALT_HUMAN
• UniProt AC: P07902
• Protein Name: Galactose-1-phosphate uridylyltransferase
• Gene Name: GALT
• Organism: Homo sapiens (Human).
• Sequence Length: 379
• Protein Description: Plays an important role in galactose metabolism..
• Protein Sequence: MSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGAIRANGEVNPQYDSTFLFDNDFPALQPDAPSPGPSDHPLFQAKSARGVCKVMCFHPWSDVTLPLMSVPEIRAVVDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQAYKSQHGEPLLMEYSRQELLRKERLVLTSEHWLVLVPFWATWPYQTLLLPRRHVRRLPELTPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGSEAGANWNHWQLHAHYYPPLLRSATVRKFMVGYEMLAQAQRDLTPEQAAERLRALPEVHYHLGQKDRETATIA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
63	Ubiquitination	QVEPQLLKTVPRHDP CCCCHHHHCCCCCCC	56.95	-
89	Phosphorylation	NGEVNPQYDSTFLFD CCEECCCCCCEEECC	17.08	26657352
108	Phosphorylation	ALQPDAPSPGPSDHP CCCCCCCCCCCCCCH	44.18	26657352
112	Phosphorylation	DAPSPGPSDHPLFQA CCCCCCCCCCHHHHH	55.24	28450419
120	Ubiquitination	DHPLFQAKSARGVCK CCHHHHHHHCCCCEE	33.59	21906983
135	Phosphorylation	VMCFHPWSDVTLPLM EEEECCCCCCCCCCC	27.01	25072903
138	Phosphorylation	FHPWSDVTLPLMSVP ECCCCCCCCCCCCHH	27.87	25072903
143	Phosphorylation	DVTLPLMSVPEIRAV CCCCCCCCHHHHHHH	42.05	25072903
210	Ubiquitination	ERSQQAYKSQHGEPL HHHHHHHHHHCCCCH	46.81	-
339	Phosphorylation	VRKFMVGYEMLAQAQ HHHHHHHHHHHHHHH	6.17	-
350	Phosphorylation	AQAQRDLTPEQAAER HHHHHCCCHHHHHHH	29.12	26074081
366	Phosphorylation	RALPEVHYHLGQKDR HHCCHHHHHCCCCCC	12.15	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GALT_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GALT_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GALT_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PCH2_HUMAN	TRIP13	physical	16189514
ACK1_HUMAN	TNK2	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 230400: Galactosemia (GALCT)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.