dbPTM

GNT1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GNT1_YEAST
UniProt AC	Q12096
Protein Name	Glucose N-acetyltransferase 1
Gene Name	GNT1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	491
Subcellular Localization	Golgi apparatus membrane Single-pass type II membrane protein . Vacuole membrane Single-pass type II membrane protein .
Protein Description	N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans..
Protein Sequence	MRLISKRRIRFIVFILFGVLTVFVVSRLVVHFQYNQEIKFYKKYFQQRKDGLHEIYNPLEIKQIPKETIDDLYTARLDKELKNGEVIEWSKFAYVNYVTNADYLCNTLIIFNDLKQEFETKAKLVLLISKDLLDPNTSSNVAYISSLLNKIQAIDEDQVVIKLIDNIVKPKDTTPWNESLTKLLVFNQTEFDRVIYLDNDAILRSSLDELFFLPNYIKFAAPLTYWFLSNSDLEKSYHETRHREKQPINLQSYTKVLTKRIGKGQMIYNHLPSLPHSLYLNSNNIAQDIISSTSSLSPLFDFQSSKKVGKLKFASNLMVINPSKEAFDEIVNVMLPKILNKKEKYDMDLINEEMYNLKKIIYKQFIFFRKVRKLFKPEVLVLPFARYGLLTGSLRNPRHYSIIYNDVLGYKTLDNDGNDIPVGLNDSVAYSKYIHFSDYPLAKPWNYPSMKEFECIVKEEDAEDSKLEHQACDLWNSVYASYIQSREICLV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
136	N-linked_Glycosylation	SKDLLDPNTSSNVAY EHHHCCCCCCCCHHH	52.86	-
177	N-linked_Glycosylation	PKDTTPWNESLTKLL CCCCCCCCHHHHHHH	30.13	-
187	N-linked_Glycosylation	LTKLLVFNQTEFDRV HHHHHEECCCCCCEE	40.14	-
245	Acetylation	HETRHREKQPINLQS HHHCCCCCCCCCHHH	62.42	24489116
425	N-linked_Glycosylation	NDIPVGLNDSVAYSK CCCCCCCCCCCCCCC	33.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GNT1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GNT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GNT1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATG20_YEAST	ATG20	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
TAL2_YEAST	NQM1	genetic	27708008
UPF3_YEAST	UPF3	genetic	27708008
PFD3_YEAST	PAC10	genetic	27708008
RAD14_YEAST	RAD14	genetic	27708008
SCS22_YEAST	SCS22	genetic	27708008
ATU1_YEAST	PCA1	genetic	27708008
SNT1_YEAST	SNT1	genetic	27708008
VMS1_YEAST	VMS1	genetic	27708008
CYPH_YEAST	CPR1	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
CYPD_YEAST	CPR5	genetic	27708008
LSM6_YEAST	LSM6	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
SPO74_YEAST	SPO74	genetic	27708008
KIP3_YEAST	KIP3	genetic	27708008
PSA3_YEAST	PRE9	genetic	27708008
STB5_YEAST	STB5	genetic	27708008
CUL8_YEAST	RTT101	genetic	27708008
BNA3_YEAST	BNA3	genetic	27708008
ASF1_YEAST	ASF1	genetic	27708008
MOG1_YEAST	MOG1	genetic	27708008
MGR3L_YEAST	YKL133C	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
YPT52_YEAST	YPT52	genetic	27708008
ALY1_YEAST	ALY1	genetic	27708008
PDR8_YEAST	PDR8	genetic	27708008
SWC7_YEAST	SWC7	genetic	27708008
YL415_YEAST	YLR415C	genetic	27708008
AIM34_YEAST	AIM34	genetic	27708008
PGM2_YEAST	PGM2	genetic	27708008
MGR3_YEAST	MGR3	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
SGT2_YEAST	SGT2	genetic	27708008
CRC1_YEAST	CRC1	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
HSP7F_YEAST	SSE1	genetic	27708008
KAR3_YEAST	KAR3	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GNT1_YEAST

Related Literatures of Post-Translational Modification