| UniProt ID | RUX_DROME | |
|---|---|---|
| UniProt AC | P50445 | |
| Protein Name | Cell cycle negative regulator roughex | |
| Gene Name | rux | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 335 | |
| Subcellular Localization | ||
| Protein Description | Negative regulator of both mitosis and meiosis. Required for the establishment of the G1 phase in the developing eye.. | |
| Protein Sequence | MSAPEEHKETPLEVIHEFINGVDDGTIRRDLGEDCILSFYSRNVRGAKAITGFLRNQLTMRYKHEGFEEAAQIEWGDELLLKARFGRSFDSERRRIYEEKERTGTTLHVRPESDDEEVNEKFSSTLITPPRPSSYNLNSLKYVEACGLLNKRNEHIYGGLDMGESCAVHLTLGYRSTFLPGGQVSGFEICLAVYDRGLTSLKRSTLIPPLCSISFARRASARCNPTTDDEEDTEEDSTPPTARRCVRRTLFTEENTQKEEDADFIPVVEQEQPAPQEQPAPQQAEETGEVVIPVDISTALKTTNFSSCTPRKRQQATNGNEVVRKRATGPRRMRF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 88 | Phosphorylation | LKARFGRSFDSERRR HHHHHCCCCHHHHHH | 33.51 | 22817900 | |
| 91 | Phosphorylation | RFGRSFDSERRRIYE HHCCCCHHHHHHHHH | 30.87 | 22817900 | |
| 113 | Phosphorylation | TLHVRPESDDEEVNE EEEECCCCCCHHHHH | 53.71 | 19429919 | |
| 309 | Phosphorylation | TTNFSSCTPRKRQQA CCCCCCCCCCHHHHC | 28.24 | 27626673 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RUX_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RUX_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RUX_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ER_DROME | e(r) | physical | 15575970 | |
| BCD_DROME | bcd | physical | 15575970 | |
| CSN3_DROME | CSN3 | physical | 15575970 | |
| CEG1A_DROME | CenG1A | physical | 15575970 | |
| DIMM_DROME | dimm | physical | 15575970 | |
| PUF68_DROME | pUf68 | physical | 15575970 | |
| DFD_DROME | Dfd | physical | 15575970 | |
| LIP3_DROME | Lip3 | physical | 15575970 | |
| CCNE_DROME | CycE | physical | 15575970 | |
| CRN_DROME | crn | physical | 15575970 | |
| DAN_DROME | dan | physical | 15575970 | |
| GELS_DROME | Gel | physical | 15575970 | |
| BOWEL_DROME | bowl | physical | 15575970 | |
| SLY1_DROME | Slh | physical | 15575970 | |
| CKS1_DROME | Cks30A | physical | 22036573 | |
| CDK1_DROME | cdc2 | physical | 22036573 | |
| CCNB3_DROME | CycB3 | physical | 22036573 | |
| EBI_DROME | ebi | genetic | 10215623 | |
| STAR_DROME | S | genetic | 8020091 | |
| ASTE_DROME | ast | genetic | 8020091 | |
| TWINE_DROME | twe | genetic | 8020091 | |
| TWINE_DROME | twe | genetic | 8020092 | |
| CCNB_DROME | CycB | genetic | 8020092 | |
| CCNA_DROME | CycA | genetic | 8020091 | |
| CCNA_DROME | CycA | genetic | 8020092 | |
| CCNA_DROME | CycA | genetic | 9000053 | |
| RAS1_DROME | Ras85D | genetic | 8020091 | |
| MPIP_DROME | stg | genetic | 8020091 | |
| MPIP_DROME | stg | genetic | 9000053 | |
| CCNA_DROME | CycA | physical | 11027291 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
