| UniProt ID | DFD_DROME | |
|---|---|---|
| UniProt AC | P07548 | |
| Protein Name | Homeotic protein deformed | |
| Gene Name | Dfd | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 586 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Homeotic protein controlling Drosophila head development. Transcriptional activator of the apoptotic activator protein rpr in cells at the maxillary/mandibular boundary.. | |
| Protein Sequence | MSSFLMGYPHAPHHVQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQQHLSNNNNNGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQQQSDLMTNLQLHIKQDYDLTAL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of DFD_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DFD_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DFD_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DFD_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NOTCH_DROME | N | genetic | 9832527 | |
| FSH_DROME | fs(1)h | genetic | 9832527 | |
| EXD_DROME | exd | genetic | 9155029 | |
| EXD_DROME | exd | genetic | 9832527 | |
| GCM_DROME | gcm | genetic | 19282966 | |
| TSH_DROME | tsh | genetic | 15142974 | |
| LAMA_DROME | LanA | genetic | 7498774 | |
| DIAP1_DROME | th | genetic | 12202035 | |
| MED19_DROME | MED19 | genetic | 24786462 | |
| RPR_DROME | rpr | genetic | 12202035 | |
| HMPB_DROME | pb | genetic | 16094438 | |
| HH_DROME | hh | genetic | 7498774 | |
| CNC_DROME | cnc | genetic | 7498774 | |
| CNC_DROME | cnc | genetic | 10952900 | |
| TITIN_DROME | sls | genetic | 7498774 | |
| EXD_DROME | exd | physical | 20634319 | |
| EXD_DROME | exd | physical | 9405369 | |
| EXD_DROME | exd | physical | 9878063 | |
| MED19_DROME | MED19 | physical | 24786462 | |
| HTH_DROME | hth | physical | 20634319 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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