dbPTM

ASTE_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ASTE_DROME
UniProt AC	Q9VPW1
Protein Name	Protein asteroid
Gene Name	ast
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	854
Subcellular Localization
Protein Description	May function in EGF receptor signaling. May play a role in compound eye morphogenesis..
Protein Sequence	MGVRGLTSYIAQRAEIYLKPHELHSTALVIDGDNLSCNLYKDVTGSYSAFGGDYDDFYRAVVQFFQVLAECNIRPYVLMDGGYEERKLRTVSTRLRNKISVIKKINPNASITLFPLHLKEVFVDAVRDCGVPVMRCVFEADDELAALARKLNCPVLSYDSDFYIHNVKYIPLITLTVKVLTKQVKDKNSSNQKDSRDLRHCEAKNVKKRTRANKIVTGIQTTGLTASTKGSSKTYKYLDCCIYRVSHLCGRGTLSPEKLPLFAALLGNDYIARSAFKNFFAAGMGKAGRSRKLKLQQKRIQVILTWLKEETAESALAKVLSRLKKNQRDSLVSQVNAAISGYSNELCHAYDYFDEHYENAFPYIEPVSEEECSDDEHSSSSDEKFSDVEEGEDQEEADNQDEEQQEENQDVDSGDEEEEEADEGLELEVEDKTLLFPQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFHDSNEVALPILNYVFALLHHVECEKIELPLEVDMDIEGSTVPYLTYLTRALRVTNVRYFKMPIEKKPAYPFDPLSPDARHLRAVFEDNAPNADTEKLFSKLDQLPEDLRLYFLAIIYWLHRSEHCDLLHLHSLILSLVVLRTIDVTIPAEREVKTFLKRFGKTLKAERAVRDKEAAEGIKRGIKPALLELSVPDRMAHVPKSDCYLTQERLLPHFHMQEIFKKKFDLYSTTVIHAFAEFQAVVYQLNGLNSLLDFPLLSPRMNQLYCGAFLYNMYDVLRNRADVRYHVENFLLPDSKLMFDFYCYLYDWCAEFIPTWKRLEVDPTAAKALQKKRLKKQRQAARKVELREAIADPNAEMVEDADPENDFFDLNNKFCALKVA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
169	Phosphorylation	FYIHNVKYIPLITLT EEEECCCEEEEEEEE	11.95	22668510
176	Phosphorylation	YIPLITLTVKVLTKQ EEEEEEEEHHHHHHH	15.05	22668510
255	Phosphorylation	LCGRGTLSPEKLPLF HCCCCCCCHHHHHHH	30.74	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ASTE_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ASTE_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ASTE_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
STAR_DROME	S	genetic	7924981
EGFR_DROME	Egfr	genetic	1980740

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ASTE_DROME

Related Literatures of Post-Translational Modification