PUB3_SCHPO - dbPTM
PUB3_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PUB3_SCHPO
UniProt AC O14326
Protein Name E3 ubiquitin-protein ligase pub3
Gene Name pub3
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 786
Subcellular Localization
Protein Description E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates..
Protein Sequence MEQGAKRVRFYIVAADGLSKRDLFRQPDPFAILTVDGEQTHTTKVIKKSVNPYWNEGFEVTVKPSSVISIRLFDQKKFKKKDQGFLGLVSFRMREVGSFRSNREVSLTRPLKKSSTTNLSVLGNLVLKVAPSKIRAPAGNHSSTTANRTTSTPTTTTARTTRTTPRPTATTNTSNQSTSNSTRNGTSAATSNGTGTGAGTGASHRSSPVTNRQTNNTSALSNSNAHIMSSFEDQYGRLPPGWERRADSLGRTYYVDHNTRTTTWTRPASSTNPVHNTSSDSQRLNHQNRHLPDDSNPSLMQSDSGNDLPFGWEMRYTDTGRPYFVDHNTRTTTWVDPRNPLVRPNGGSSTVGSLMQPQSLSHLGPLPSGWEMRLTNSARVYFVDHNTKTTTWDDPRLPSALDQDVPQYKCDFRRKLIYFRSQPGMRPLPGQCNVKVRRDHIFEDSYAEIMRYSAHDLKKRLMIRFDGEDGLDYGGLSREFFFLLSHKMFDPIYCLFEYSAVDNYTLQINPHSSINPEHLNYFRFIGRVIGLAIFHRRFLDAFFVVSLYKKLLRKKVSLADMESIDAEFYRSLKWVLENDITGILDLTFSVEEDHFGEVRTVELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLVNVFDERELELLIGGISDVDVEDWKSHTEYRTYIATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEKAGTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAVENTVGFGNE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
114PhosphorylationLTRPLKKSSTTNLSV
ECCCCCCCCCCCHHH		31.1825720772
115PhosphorylationTRPLKKSSTTNLSVL
CCCCCCCCCCCHHHH		48.4025720772
116PhosphorylationRPLKKSSTTNLSVLG
CCCCCCCCCCHHHHC		27.1325720772
177PhosphorylationTTNTSNQSTSNSTRN
EECCCCCCCCCCCCC		37.7525720772
178PhosphorylationTNTSNQSTSNSTRNG
ECCCCCCCCCCCCCC		23.3625720772
179PhosphorylationNTSNQSTSNSTRNGT
CCCCCCCCCCCCCCC		33.7525720772
181PhosphorylationSNQSTSNSTRNGTSA
CCCCCCCCCCCCCCC		28.6325720772
182PhosphorylationNQSTSNSTRNGTSAA
CCCCCCCCCCCCCCC		32.1925720772
203PhosphorylationTGAGTGASHRSSPVT
CCCCCCCCCCCCCCC		22.3025720772
206PhosphorylationGTGASHRSSPVTNRQ
CCCCCCCCCCCCCCC		33.3025720772
207PhosphorylationTGASHRSSPVTNRQT
CCCCCCCCCCCCCCC		24.2825720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PUB3_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PUB3_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PUB3_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NSE6_SCHPOnse6genetic
18931302
RAD57_SCHPOrad57genetic
18931302
TLG2_SCHPOtlg2genetic
18931302
HPC2_SCHPOhip4genetic
18818364
CCR4_SCHPOccr4genetic
18818364
MU154_SCHPOmug154genetic
18818364
VPH2_SCHPOvph2genetic
18818364
ELP2_SCHPOelp2genetic
18818364
ASL1_SCHPOasl1genetic
22681890
YOI5_SCHPOSPBC1778.05cgenetic
22681890
YNG5_SCHPOSPBC691.05cgenetic
22681890
SYJ2_SCHPOsyj2genetic
22681890
YA33_SCHPOSPAC18B11.03cgenetic
22681890
PROB_SCHPOSPAC17H9.13cgenetic
22681890
LYS1_SCHPOlys3genetic
22681890
EFTS_SCHPOtsf1genetic
22681890
PCL1_SCHPOpcl1genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
ARGJ_SCHPOSPBC1271.14genetic
22681890
RBSK_SCHPOSPBC16G5.02cgenetic
22681890
YKTB_SCHPOSPAPB1E7.11cgenetic
22681890
YGRG_SCHPOSPBC365.16genetic
22681890
OBP1_SCHPOSPBC646.08cgenetic
22681890
OTC_SCHPOarg3genetic
22681890
BCA1_SCHPOeca39genetic
22681890
FSV1_SCHPOfsv1genetic
22681890
HOSM_SCHPOlys4genetic
22681890
LYS4_SCHPOlys2genetic
22681890
YEEB_SCHPOSPAC19A8.11cgenetic
22681890
PPIB_SCHPOcyp4genetic
22681890
YDT7_SCHPOSPAC6B12.07cgenetic
22681890
RLA2_SCHPOrpp201genetic
22681890
ATP5E_SCHPOatp15genetic
22681890
FKBP4_SCHPOfkbp39genetic
22681890
VPS72_SCHPOswc2genetic
22681890
MAD2_SCHPOmad2genetic
22681890
ARG56_SCHPOarg11genetic
22681890
MED1_SCHPOpmc2genetic
22681890
RL16B_SCHPOrpl1601genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
RFP2_SCHPOrfp2genetic
22681890
YNH1_SCHPOSPBC32H8.01cgenetic
22681890
YD22_SCHPOSPAC56F8.02genetic
22681890
YHD3_SCHPOSPBC1683.03cgenetic
22681890
SKI3_SCHPOSPCC1919.05genetic
22681890
ATF31_SCHPOatf31genetic
22681890
RL19B_SCHPOrpl1902genetic
22681890
FAT2_SCHPOSPCC1827.03cgenetic
22681890
NPY1_SCHPOSPBC1778.03cgenetic
22681890
YLF7_SCHPOSPAC30C2.07genetic
22681890
YGQ9_SCHPOSPBC1703.09genetic
22681890
ASSY_SCHPOarg12genetic
22681890
RL7B_SCHPOrpl702genetic
22681890
APS1_SCHPOaps1genetic
22681890
RS4A_SCHPOrps401genetic
22681890
MUG73_SCHPOmug73genetic
22681890
YNSK_SCHPOany1physical
26771498
YHK5_SCHPOSPBC660.05physical
26771498
DHH1_SCHPOste13physical
26771498
ALY1_SCHPOSPBC839.02physical
26771498
YHP4_SCHPOrmn1physical
26771498
YORQ_SCHPOSPBP8B7.26physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PUB3_SCHPO

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Related Literatures of Post-Translational Modification

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